SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		3 / 3 ILE A  19
LEU A  22
VAL A  26
 None
 0.24A 1mz9B-1p7nA:
undetectable		 1mz9B-1p7nA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 5 ASP A  52
THR A 133
LEU A 129
LEU A  48
 None
 1.07A 1u18B-1p7nA:
undetectable		 1u18B-1p7nA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 6 LEU A  31
GLU A  39
ILE A  35
PRO A  34
 None
 0.94A 2fcnA-1p7nA:
undetectable
2fcnB-1p7nA:
undetectable		 2fcnA-1p7nA:
19.53
2fcnB-1p7nA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 5 ALA A 134
ALA A  83
ALA A  82
GLN A  76
 None
 0.85A 2nyrB-1p7nA:
undetectable		 2nyrB-1p7nA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 7 ASP A  52
VAL A  53
ALA A 136
PRO A  13
 None
 1.05A 2q6oA-1p7nA:
undetectable		 2q6oA-1p7nA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		3 / 3 PHE A 140
ILE A  60
ASP A  52
 None
 0.68A 5cswA-1p7nA:
undetectable		 5cswA-1p7nA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		3 / 3 PHE A 140
ILE A  60
ASP A  52
 None
 0.65A 5cswB-1p7nA:
undetectable		 5cswB-1p7nA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 8 GLN A  78
ALA A 139
GLN A 138
SER A 135
 None
 1.14A 5km8A-1p7nA:
undetectable
5km8B-1p7nA:
undetectable		 5km8A-1p7nA:
24.28
5km8B-1p7nA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27
(Rous
sarcoma
virus) 		4 / 7 LEU A  68
ASP A  71
TRP A  73
LEU A  77
 None
 1.03A 5nwvA-1p7nA:
0.0		 5nwvA-1p7nA:
11.31