SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p8r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA2_0
(ACTINOMYCIN D)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 4 THR A 135
PRO A 132
THR A 131
PRO A 157
 None
 1.46A 1a7yA-1p8rA:
undetectable
1a7yC-1p8rA:
undetectable		 1a7yA-1p8rA:
3.81
1a7yC-1p8rA:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 8 ALA A 296
GLU A 287
ALA A 243
THR A 244
 None
 0.92A 1ie4B-1p8rA:
undetectable
1ie4D-1p8rA:
undetectable		 1ie4B-1p8rA:
21.24
1ie4D-1p8rA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.48A 1v8bA-1p8rA:
2.3		 1v8bA-1p8rA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.48A 1v8bB-1p8rA:
undetectable		 1v8bB-1p8rA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 ILE A 208
VAL A 123
PHE A 231
LEU A 299
ILE A 264
 None
 0.99A 1xozA-1p8rA:
undetectable		 1xozA-1p8rA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 6 LEU A 179
TYR A 176
ILE A 190
GLY A 142
 None
None
None
S2C  A 551 ( 3.9A)
 0.86A 2du8A-1p8rA:
3.1		 2du8A-1p8rA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 6 LEU A 179
TYR A 176
ILE A 190
GLY A 142
 None
None
None
S2C  A 551 ( 3.9A)
 0.79A 2du8B-1p8rA:
3.1		 2du8B-1p8rA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 8 THR A 131
GLY A 185
THR A 127
ILE A 129
 None
 0.82A 2f9wA-1p8rA:
undetectable
2f9wB-1p8rA:
undetectable		 2f9wA-1p8rA:
22.19
2f9wB-1p8rA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 8 ALA A 296
GLY A 257
LEU A 236
GLY A 235
ASP A 124
 None
None
None
None
MN  A 500 (-2.6A)
 1.50A 2yfxA-1p8rA:
undetectable		 2yfxA-1p8rA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		3 / 3 SER A 137
GLU A 277
ASP A 274
 S2C  A 551 (-3.3A)
S2C  A 551 (-3.6A)
None
 0.75A 2zulA-1p8rA:
3.2		 2zulA-1p8rA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 5 HIS A 141
ASP A 128
HIS A 126
ASP A 124
 S2C  A 551 (-3.7A)
MN  A 501 ( 2.6A)
MN  A 500 ( 3.2A)
MN  A 500 (-2.6A)
 1.25A 3c0zA-1p8rA:
13.3		 3c0zA-1p8rA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.47A 3ce6D-1p8rA:
2.6		 3ce6D-1p8rA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		3 / 3 SER A 137
GLU A 277
ASP A 274
 S2C  A 551 (-3.3A)
S2C  A 551 (-3.6A)
None
 0.72A 3dmhA-1p8rA:
undetectable		 3dmhA-1p8rA:
21.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN0_A_DMOA551_1
(ARGINASE-1)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 9 HIS A 126
ASN A 130
SER A 136
ASP A 183
GLU A 186
 MN  A 500 ( 3.2A)
S2C  A 551 (-3.9A)
S2C  A 551 ( 3.7A)
S2C  A 551 (-2.8A)
S2C  A 551 ( 4.2A)
 1.19A 3gn0A-1p8rA:
55.8		 3gn0A-1p8rA:
87.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN0_A_DMOA551_1
(ARGINASE-1)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		9 / 9 HIS A 126
ASP A 128
ASN A 130
SER A 137
HIS A 141
GLY A 142
ASP A 183
GLU A 186
THR A 246
 MN  A 500 ( 3.2A)
MN  A 501 ( 2.6A)
S2C  A 551 (-3.9A)
S2C  A 551 (-3.3A)
S2C  A 551 (-3.7A)
S2C  A 551 ( 3.9A)
S2C  A 551 (-2.8A)
S2C  A 551 ( 4.2A)
S2C  A 551 ( 4.3A)
 0.46A 3gn0A-1p8rA:
55.8		 3gn0A-1p8rA:
87.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN0_B_DMOB552_1
(ARGINASE-1)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 9 HIS A 126
ASN A 130
SER A 136
ASP A 183
GLU A 186
 MN  A 500 ( 3.2A)
S2C  A 551 (-3.9A)
S2C  A 551 ( 3.7A)
S2C  A 551 (-2.8A)
S2C  A 551 ( 4.2A)
 1.14A 3gn0B-1p8rA:
56.0		 3gn0B-1p8rA:
87.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN0_B_DMOB552_1
(ARGINASE-1)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		9 / 9 HIS A 126
ASP A 128
ASN A 130
SER A 137
HIS A 141
GLY A 142
ASP A 183
GLU A 186
THR A 246
 MN  A 500 ( 3.2A)
MN  A 501 ( 2.6A)
S2C  A 551 (-3.9A)
S2C  A 551 (-3.3A)
S2C  A 551 (-3.7A)
S2C  A 551 ( 3.9A)
S2C  A 551 (-2.8A)
S2C  A 551 ( 4.2A)
S2C  A 551 ( 4.3A)
 0.44A 3gn0B-1p8rA:
56.0		 3gn0B-1p8rA:
87.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.50A 3ondA-1p8rA:
undetectable		 3ondA-1p8rA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.49A 3ondB-1p8rA:
undetectable		 3ondB-1p8rA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 8 THR A 244
ARG A  21
GLY A  99
SER A  16
 None
 1.10A 3tzfB-1p8rA:
undetectable		 3tzfB-1p8rA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 8 VAL A 145
CYH A 168
ILE A 174
ILE A 108
 None
 0.92A 4afgD-1p8rA:
0.0
4afgE-1p8rA:
0.0		 4afgD-1p8rA:
23.51
4afgE-1p8rA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 LEU A 219
GLY A 178
MET A 212
THR A 215
GLY A 257
 None
 0.98A 4dc3A-1p8rA:
2.4		 4dc3A-1p8rA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 8 GLY A 305
TYR A 254
LEU A 258
GLU A 262
 None
 0.86A 4fgzA-1p8rA:
undetectable		 4fgzA-1p8rA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 8 TYR A 254
LEU A 258
GLU A 262
TYR A 265
 None
 0.67A 4fgzA-1p8rA:
undetectable		 4fgzA-1p8rA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 8 TYR A 254
LEU A 258
GLU A 262
TYR A 265
 None
 0.64A 4fgzB-1p8rA:
undetectable		 4fgzB-1p8rA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 6 ASP A 183
ASP A 232
ASP A 128
GLU A 186
 S2C  A 551 (-2.8A)
MN  A 500 (-3.1A)
MN  A 501 ( 2.6A)
S2C  A 551 ( 4.2A)
 1.32A 4gkhJ-1p8rA:
undetectable		 4gkhJ-1p8rA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		3 / 3 ASP A 124
ASP A 128
ASN A 139
 MN  A 500 (-2.6A)
MN  A 501 ( 2.6A)
None
 0.81A 4q5mA-1p8rA:
undetectable		 4q5mA-1p8rA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		3 / 3 ASP A  49
LEU A  97
GLY A  12
 None
 0.50A 4xmfA-1p8rA:
undetectable		 4xmfA-1p8rA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 LEU A 229
VAL A 123
ILE A 177
LEU A 220
LEU A 219
 None
 1.27A 4yvpB-1p8rA:
undetectable		 4yvpB-1p8rA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 9 THR A 261
GLY A 305
THR A  43
LEU A  40
LEU A  36
 None
 1.29A 4ze0A-1p8rA:
undetectable		 4ze0A-1p8rA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.49A 5axdA-1p8rA:
2.2		 5axdA-1p8rA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.49A 5axdC-1p8rA:
2.5		 5axdC-1p8rA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		3 / 3 ILE A 177
ILE A 174
MET A 212
 None
 0.64A 5i9yA-1p8rA:
undetectable		 5i9yA-1p8rA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 4 GLN A  88
VAL A  84
GLU A   9
ILE A  11
 None
 1.26A 5jncA-1p8rA:
0.0		 5jncA-1p8rA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.40A 5m5kB-1p8rA:
3.1		 5m5kB-1p8rA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.47A 5m66C-1p8rA:
undetectable		 5m66C-1p8rA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		4 / 6 GLY A 185
PRO A 184
THR A 134
SER A 136
 None
None
None
S2C  A 551 ( 3.7A)
 1.01A 5ny7A-1p8rA:
1.9		 5ny7A-1p8rA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 11 VAL A  96
ALA A  13
SER A 107
LEU A  80
ASN A  77
 None
 0.97A 5x6yA-1p8rA:
3.5		 5x6yA-1p8rA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 10 VAL A  96
ALA A  13
SER A 107
LEU A  80
ASN A  77
 None
 0.93A 5x6yB-1p8rA:
undetectable		 5x6yB-1p8rA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 11 VAL A  96
ALA A  13
SER A 107
LEU A  80
ASN A  77
 None
 1.06A 5x6yC-1p8rA:
4.5		 5x6yC-1p8rA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 PRO A 247
THR A 246
GLU A 277
HIS A 141
THR A 127
 None
S2C  A 551 ( 4.3A)
S2C  A 551 (-3.6A)
S2C  A 551 (-3.7A)
None
 1.31A 5xioB-1p8rA:
2.5		 5xioB-1p8rA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 VAL A  84
LEU A  36
LEU A  97
SER A 107
LEU A 270
 None
 1.08A 6b0iB-1p8rA:
2.9		 6b0iB-1p8rA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 VAL A  84
LEU A  36
LEU A  97
SER A 107
LEU A 270
 None
 1.01A 6b0lB-1p8rA:
4.4		 6b0lB-1p8rA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)		 1p8r ARGINASE 1
(Rattus
norvegicus) 		5 / 12 HIS A 126
ASP A 234
THR A 244
GLY A 142
HIS A 141
 MN  A 500 ( 3.2A)
MN  A 500 ( 2.1A)
None
S2C  A 551 ( 3.9A)
S2C  A 551 (-3.7A)
 1.45A 6f3nB-1p8rA:
2.2		 6f3nB-1p8rA:
21.68