SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_B_MTXB164_2 (DIHYDROFOLATE REDUCTASE)	1p9d	UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A (Homo sapiens)	4 / 4	PHE U 15 LYS U 8 ILE U 32 THR U 4	None	1.39A	3ia4B-1p9dU: undetectable	3ia4B-1p9dU: 20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_J_CHDJ102_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1p9d	UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A (Homo sapiens)	4 / 7	ILE U 5 LEU U 28 ARG U 65 LEU U 55	None	0.96A	5b1aA-1p9dU: undetectable 5b1aJ-1p9dU: undetectable	5b1aA-1p9dU: 8.56 5b1aJ-1p9dU: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B3S_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1p9d	UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A (Homo sapiens)	4 / 7	ILE U 5 LEU U 28 ARG U 65 LEU U 55	None	0.95A	5b3sA-1p9dU: undetectable 5b3sJ-1p9dU: undetectable	5b3sA-1p9dU: 8.56 5b3sJ-1p9dU: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1p9d	UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A (Homo sapiens)	4 / 7	ILE U 5 LEU U 28 ARG U 65 LEU U 55	None	0.96A	5zcqA-1p9dU: undetectable 5zcqJ-1p9dU: undetectable	5zcqA-1p9dU: 8.56 5zcqJ-1p9dU: 19.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3IA4_B_MTXB164_2","DIHYDROFOLATE REDUCTASE","1p9d","UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A","Homo sapiens",4,"PHE U  15;LYS U   8;ILE U  32;THR U   4","None","1.39A","3ia4B-1p9dU:undetectable","3ia4B-1p9dU:20.99"],["5B1A_J_CHDJ102_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1p9d","UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A","Homo sapiens",4,"ILE U   5;LEU U  28;ARG U  65;LEU U  55","None","0.96A","5b1aA-1p9dU:undetectable;5b1aJ-1p9dU:undetectable","5b1aA-1p9dU:8.56;5b1aJ-1p9dU:19.23"],["5B3S_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1p9d","UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A","Homo sapiens",4,"ILE U   5;LEU U  28;ARG U  65;LEU U  55","None","0.95A","5b3sA-1p9dU:undetectable;5b3sJ-1p9dU:undetectable","5b3sA-1p9dU:8.56;5b3sJ-1p9dU:19.23"],["5ZCQ_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1p9d","UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A","Homo sapiens",4,"ILE U   5;LEU U  28;ARG U  65;LEU U  55","None","0.96A","5zcqA-1p9dU:undetectable;5zcqJ-1p9dU:undetectable","5zcqA-1p9dU:8.56;5zcqJ-1p9dU:19.23"]]