SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		4 / 6 SER A 492
THR A 491
PHE A 414
GLU A 494
 None
 1.16A 1icuA-1p9wA:
undetectable
1icuB-1p9wA:
undetectable		 1icuA-1p9wA:
22.93
1icuB-1p9wA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		4 / 6 PHE A 414
GLU A 494
SER A 492
THR A 491
 None
 1.15A 1icuA-1p9wA:
undetectable
1icuB-1p9wA:
undetectable		 1icuA-1p9wA:
22.93
1icuB-1p9wA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		4 / 6 SER A 492
THR A 491
PHE A 414
GLU A 494
 None
 1.15A 1icuC-1p9wA:
0.0
1icuD-1p9wA:
0.0		 1icuC-1p9wA:
22.93
1icuD-1p9wA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		4 / 6 PRO A 265
GLU A 495
GLN A 390
VAL A 393
 None
 1.46A 1l2iB-1p9wA:
0.0		 1l2iB-1p9wA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		5 / 12 ILE A 153
ILE A 142
LEU A 226
VAL A 207
ILE A 135
 None
 0.87A 1oipA-1p9wA:
undetectable		 1oipA-1p9wA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		5 / 8 ARG A 472
GLY A 365
THR A 362
ALA A 363
ALA A 366
 None
 1.30A 2ej3C-1p9wA:
undetectable		 2ej3C-1p9wA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		4 / 8 HIS A 352
VAL A 354
VAL A 330
LEU A 319
 None
 0.93A 2gehA-1p9wA:
undetectable		 2gehA-1p9wA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		4 / 7 LEU A 493
SER A 492
THR A 491
VAL A 486
 None
 1.15A 2uz2A-1p9wA:
undetectable		 2uz2A-1p9wA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		3 / 3 MET A 355
GLU A 292
ASP A 298
 None
 1.10A 3a25A-1p9wA:
3.0		 3a25A-1p9wA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		4 / 8 VAL A 387
GLY A 264
THR A 263
GLY A 269
 None
None
None
ANP  A 701 (-3.1A)
 0.76A 3aruA-1p9wA:
undetectable		 3aruA-1p9wA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		5 / 12 GLY A 386
LEU A 353
GLY A 258
ALA A 363
PHE A 249
 None
 0.94A 3vywC-1p9wA:
undetectable		 3vywC-1p9wA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		5 / 12 PHE A 102
ALA A 129
VAL A 164
LEU A 165
ILE A 144
 None
 1.07A 4g1bA-1p9wA:
undetectable		 4g1bA-1p9wA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		5 / 12 ILE A 259
ALA A 341
THR A 305
SER A 356
LEU A 323
 None
 1.15A 4qztC-1p9wA:
undetectable		 4qztC-1p9wA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		5 / 12 GLY A 258
LEU A 384
SER A 382
ILE A 260
HIS A 352
 None
 1.11A 5dpdA-1p9wA:
2.7		 5dpdA-1p9wA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		5 / 9 ILE A 259
VAL A 291
LEU A 319
ILE A 322
LEU A 370
 None
 1.46A 5iepA-1p9wA:
0.0		 5iepA-1p9wA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		4 / 8 HIS A 352
VAL A 354
VAL A 330
LEU A 319
 None
 0.74A 5tt3F-1p9wA:
undetectable		 5tt3F-1p9wA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		3 / 3 TYR A 425
ALA A 406
LEU A 422
 None
 0.67A 6ag0C-1p9wA:
undetectable		 6ag0C-1p9wA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 1p9w GENERAL SECRETION
PATHWAY PROTEIN E
(Vibrio
cholerae) 		5 / 12 ILE A 380
LEU A 454
GLY A 365
ILE A 335
LEU A 261
 None
 1.07A 6dwnC-1p9wA:
undetectable		 6dwnC-1p9wA:
11.06