SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pcs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.35A 1oe1A-1pcsA:
undetectable		 1oe1A-1pcsA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		5 / 5 HIS A  37
CYH A  84
PRO A  86
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 4.9A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.71A 1oe2A-1pcsA:
6.7		 1oe2A-1pcsA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.38A 1oe3A-1pcsA:
undetectable		 1oe3A-1pcsA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.40A 2fqdA-1pcsA:
undetectable		 2fqdA-1pcsA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.37A 2fqeA-1pcsA:
undetectable		 2fqeA-1pcsA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.36A 2fqfA-1pcsA:
undetectable		 2fqfA-1pcsA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.36A 2fqgA-1pcsA:
undetectable		 2fqgA-1pcsA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.36A 2xxgA-1pcsA:
6.3		 2xxgA-1pcsA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		5 / 5 HIS A  37
CYH A  84
PRO A  86
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 4.9A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.76A 2xxgC-1pcsA:
6.4		 2xxgC-1pcsA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A  99
GLY A  78
THR A  79
 None
 0.57A 3iazA-1pcsA:
undetectable		 3iazA-1pcsA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLY A  94
TRP A  29
VAL A   3
 None
 0.57A 3n62B-1pcsA:
undetectable		 3n62B-1pcsA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLY A  94
TRP A  29
VAL A   3
 None
 0.58A 3n65B-1pcsA:
undetectable		 3n65B-1pcsA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLY A  94
TRP A  29
VAL A   3
 None
 0.58A 3n66B-1pcsA:
undetectable		 3n66B-1pcsA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 275 ( 3.1A)
CU  A 275 ( 2.2A)
CU  A 275 ( 3.1A)
CU  A 275 ( 2.6A)
 0.33A 4ef3A-1pcsA:
undetectable		 4ef3A-1pcsA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1pcs PLASTOCYANIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLY A  94
TRP A  29
VAL A   3
 None
 0.54A 5vuoB-1pcsA:
undetectable		 5vuoB-1pcsA:
13.57