SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pcv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.77A 1dscC-1pcvA:
undetectable		 1dscC-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.87A 1fjaC-1pcvA:
undetectable		 1fjaC-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.87A 1fjaD-1pcvA:
undetectable		 1fjaD-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.86A 1i3wG-1pcvA:
undetectable		 1i3wG-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.86A 1i3wH-1pcvA:
undetectable		 1i3wH-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.87A 1unjL-1pcvA:
undetectable		 1unjL-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.83A 1unjL-1pcvA:
undetectable		 1unjL-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.87A 1unjR-1pcvA:
undetectable		 1unjR-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.84A 1unjR-1pcvA:
undetectable		 1unjR-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.81A 1unjW-1pcvA:
undetectable		 1unjW-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.84A 1unjX-1pcvA:
undetectable		 1unjX-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.84A 1unjX-1pcvA:
undetectable		 1unjX-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.84A 1unmE-1pcvA:
undetectable		 1unmE-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.80A 1unmE-1pcvA:
undetectable		 1unmE-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.86A 1unmF-1pcvA:
undetectable		 1unmF-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.80A 1unmF-1pcvA:
undetectable		 1unmF-1pcvA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		4 / 5 GLY A 118
PRO A 112
ALA A 111
ILE A 123
 None
 0.81A 2aofA-1pcvA:
undetectable		 2aofA-1pcvA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		5 / 12 GLY A  76
GLY A 103
GLY A  64
LEU A 137
ASP A 102
 None
 1.02A 3gczA-1pcvA:
undetectable		 3gczA-1pcvA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 GLY A  47
ILE A 202
VAL A 201
 None
 0.47A 3nv6A-1pcvA:
undetectable		 3nv6A-1pcvA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		4 / 8 THR A  81
ALA A 178
ASP A 184
SER A 188
 None
 1.06A 5l5fY-1pcvA:
undetectable
5l5fZ-1pcvA:
0.0		 5l5fY-1pcvA:
22.04
5l5fZ-1pcvA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 THR A 148
PRO A 134
ARG A 135
 None
 0.82A 5nd7B-1pcvA:
undetectable		 5nd7B-1pcvA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1pcv OSMOTIN
(Nicotiana
tabacum) 		3 / 3 GLY A  47
THR A  49
ASN A 105
 None
 0.48A 5odiG-1pcvA:
undetectable		 5odiG-1pcvA:
14.67