SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pdr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1pdr HUMAN DISCS LARGE
PROTEIN
(Homo
sapiens) 		3 / 3 LEU A 495
LEU A 532
PHE A 493
 None
 0.67A 2pgrA-1pdrA:
undetectable		 2pgrA-1pdrA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1pdr HUMAN DISCS LARGE
PROTEIN
(Homo
sapiens) 		4 / 8 ALA A 528
ALA A 531
ILE A 489
GLU A 487
 None
 0.81A 3dtuC-1pdrA:
undetectable
3dtuD-1pdrA:
undetectable		 3dtuC-1pdrA:
11.07
3dtuD-1pdrA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 1pdr HUMAN DISCS LARGE
PROTEIN
(Homo
sapiens) 		3 / 3 GLU A 549
ARG A 552
GLN A 544
 None
 0.91A 4rtbA-1pdrA:
undetectable		 4rtbA-1pdrA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1pdr HUMAN DISCS LARGE
PROTEIN
(Homo
sapiens) 		5 / 10 LEU A 520
ILE A 489
GLY A 488
GLY A 486
ALA A 528
 None
 1.05A 5o96C-1pdrA:
undetectable
5o96D-1pdrA:
undetectable		 5o96C-1pdrA:
16.87
5o96D-1pdrA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1pdr HUMAN DISCS LARGE
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 520
GLY A 488
GLU A 484
GLY A 486
ALA A 528
 None
 0.93A 5o96G-1pdrA:
undetectable		 5o96G-1pdrA:
16.87