SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pfc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1pfc IGG1 PFC' FC
(Cavia
porcellus) 		4 / 8 ILE A 441
TRP A 417
ARG A 443
ASN A 418
 None
 1.21A 6hisA-1pfcA:
undetectable
6hisB-1pfcA:
undetectable		 6hisA-1pfcA:
20.56
6hisB-1pfcA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1pfc IGG1 PFC' FC
(Cavia
porcellus) 		4 / 8 ILE A 441
TRP A 417
ARG A 443
ASN A 418
 None
 1.19A 6hisD-1pfcA:
undetectable
6hisE-1pfcA:
undetectable		 6hisD-1pfcA:
20.56
6hisE-1pfcA:
20.56