SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pg7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 1pg7 MURINE ANTIBODY 6A6
FAB FRAGMENT
(Mus
musculus) 		4 / 8 SER X  74
PHE X  29
ALA X  24
LEU X  34
 None
 1.05A 2bxkA-1pg7X:
undetectable		 2bxkA-1pg7X:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 1pg7 MURINE ANTIBODY 6A6
FAB FRAGMENT
(Mus
musculus) 		5 / 10 SER X  74
PHE X  29
ALA X  24
LEU X   4
LEU X  34
 None
 1.09A 2bxqA-1pg7X:
undetectable		 2bxqA-1pg7X:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 1pg7 HUMANIZED ANTIBODY
D3H44
MURINE ANTIBODY 6A6
FAB FRAGMENT
(Homo
sapiens;
Mus
musculus;
Mus
musculus) 		4 / 7 TYR H  33
ASP H  52
TYR X 102
HIS X  32
 None
 1.45A 2bytA-1pg7H:
0.0		 2bytA-1pg7H:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 1pg7 HUMANIZED ANTIBODY
D3H44
MURINE ANTIBODY 6A6
FAB FRAGMENT
(Homo
sapiens;
Mus
musculus;
Mus
musculus) 		4 / 7 TYR H  33
ASP H  52
TYR X 102
HIS X  32
 None
 1.45A 2bytD-1pg7H:
0.0		 2bytD-1pg7H:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 1pg7 MURINE ANTIBODY 6A6
FAB FRAGMENT
(Mus
musculus) 		5 / 12 GLY X 106
ILE X  80
ILE X  48
VAL X  18
ILE X  20
 None
 0.92A 2hs1B-1pg7X:
undetectable		 2hs1B-1pg7X:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_D_LEUD1883_0
(AMINOACYL-TRNA
SYNTHETASE)		 1pg7 HUMANIZED ANTIBODY
D3H44
MURINE ANTIBODY 6A6
FAB FRAGMENT
(Homo
sapiens;
Mus
musculus;
Mus
musculus) 		4 / 5 TYR H  33
ASP H  52
TYR X 102
HIS X  32
 None
 1.42A 2v0gD-1pg7H:
undetectable		 2v0gD-1pg7H:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1pg7 HUMANIZED ANTIBODY
D3H44
(Homo
sapiens;
Mus
musculus) 		3 / 3 THR H 110
GLU H 148
HIS H 200
 None
 0.71A 3g1uB-1pg7H:
undetectable		 3g1uB-1pg7H:
19.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1pg7 MURINE ANTIBODY 6A6
FAB FRAGMENT
(Mus
musculus) 		4 / 5 VAL X   2
TYR X  27
ARG X  94
TYR X 102
 None
 0.40A 4m7kH-1pg7X:
22.7		 4m7kH-1pg7X:
62.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1pg7 HUMANIZED ANTIBODY
D3H44
(Homo
sapiens;
Mus
musculus) 		4 / 5 TYR H 176
LEU H 108
PRO H  41
LEU H  11
 None
 1.41A 5eshA-1pg7H:
undetectable		 5eshA-1pg7H:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 1pg7 MURINE ANTIBODY 6A6
FAB FRAGMENT
(Mus
musculus) 		3 / 3 SER X 203
ALA X 198
VAL X 197
 None
 0.50A 5xiwC-1pg7X:
undetectable		 5xiwC-1pg7X:
14.09