SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pgr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 1.08A 1v55C-1pgrB:
undetectable
1v55J-1pgrB:
undetectable		 1v55C-1pgrB:
19.10
1v55J-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 1.03A 1v55P-1pgrB:
undetectable
1v55W-1pgrB:
undetectable		 1v55P-1pgrB:
19.10
1v55W-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 1.04A 2eijC-1pgrB:
undetectable
2eijJ-1pgrB:
undetectable		 2eijC-1pgrB:
19.10
2eijJ-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 1.08A 2eimC-1pgrB:
undetectable
2eimJ-1pgrB:
undetectable		 2eimC-1pgrB:
19.10
2eimJ-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 1.07A 2einC-1pgrB:
undetectable
2einJ-1pgrB:
undetectable		 2einC-1pgrB:
19.10
2einJ-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 6 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 1.05A 2einP-1pgrB:
undetectable
2einW-1pgrB:
undetectable		 2einP-1pgrB:
19.10
2einW-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 0.98A 2zxwC-1pgrB:
undetectable
2zxwJ-1pgrB:
undetectable		 2zxwC-1pgrB:
19.10
2zxwJ-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 6 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 0.99A 3ag1C-1pgrB:
undetectable
3ag1J-1pgrB:
0.0		 3ag1C-1pgrB:
19.10
3ag1J-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 6 LEU B 187
GLY B 206
LEU B 133
SER B 134
 None
 0.64A 3aiaA-1pgrB:
undetectable		 3aiaA-1pgrB:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 0.91A 5z84C-1pgrB:
undetectable
5z84J-1pgrB:
undetectable		 5z84C-1pgrB:
19.10
5z84J-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 0.94A 5z85C-1pgrB:
undetectable
5z85J-1pgrB:
undetectable		 5z85C-1pgrB:
19.10
5z85J-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 0.88A 5zcoC-1pgrB:
undetectable
5zcoJ-1pgrB:
0.0		 5zcoC-1pgrB:
19.10
5zcoJ-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 0.96A 5zcqC-1pgrB:
undetectable
5zcqJ-1pgrB:
undetectable		 5zcqC-1pgrB:
19.10
5zcqJ-1pgrB:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pgr PROTEIN (G-CSF
RECEPTOR)
(Mus
musculus) 		4 / 7 LEU B 187
GLN B 188
LEU B 176
PHE B 174
 None
 0.93A 5zcqP-1pgrB:
undetectable
5zcqW-1pgrB:
0.0		 5zcqP-1pgrB:
19.10
5zcqW-1pgrB:
13.02