SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pgs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA2_0
(ACTINOMYCIN D)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 4 THR A 269
PRO A 176
THR A 177
PRO A 310
 None
 1.38A 1a7yA-1pgsA:
undetectable
1a7yC-1pgsA:
undetectable		 1a7yA-1pgsA:
6.49
1a7yC-1pgsA:
6.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 7 LEU A 264
LEU A 268
SER A 271
VAL A 312
 None
 0.85A 1dvxB-1pgsA:
1.1		 1dvxB-1pgsA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		5 / 12 VAL A 159
LEU A 169
GLY A 158
TYR A 275
SER A 297
 None
 1.47A 1fdsA-1pgsA:
undetectable		 1fdsA-1pgsA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 8 VAL A 146
VAL A 299
ILE A 216
LEU A 175
 None
 0.92A 1igxA-1pgsA:
undetectable		 1igxA-1pgsA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_A_STIA3_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 5 TYR A 142
LYS A 302
VAL A 100
ILE A 300
 None
 1.49A 1opjA-1pgsA:
0.0		 1opjA-1pgsA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		3 / 3 LEU A 264
LEU A 268
SER A 271
 None
 0.67A 1tlmA-1pgsA:
undetectable		 1tlmA-1pgsA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		5 / 11 GLY A 190
TYR A  62
ILE A  82
ARG A  80
VAL A 257
 None
 1.37A 1tmxA-1pgsA:
undetectable		 1tmxA-1pgsA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 7 LEU A 107
PHE A  31
PHE A 131
ILE A  78
 None
 0.77A 2opxA-1pgsA:
undetectable		 2opxA-1pgsA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 7 LEU A 264
LEU A 268
SER A 271
VAL A 312
 None
 0.89A 3d2tA-1pgsA:
undetectable		 3d2tA-1pgsA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 5 ASP A 102
ILE A  98
VAL A  65
THR A 111
 None
 1.25A 3eigA-1pgsA:
undetectable		 3eigA-1pgsA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 7 LEU A 264
LEU A 268
SER A 271
VAL A 312
 None
 0.74A 3ozkB-1pgsA:
undetectable		 3ozkB-1pgsA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		3 / 3 TYR A  85
GLU A 118
TYR A  62
 None
 0.93A 3ug8A-1pgsA:
undetectable		 3ug8A-1pgsA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 8 ASP A  99
VAL A  65
PHE A 131
LEU A 107
 None
 0.95A 4f8hA-1pgsA:
undetectable
4f8hB-1pgsA:
undetectable		 4f8hA-1pgsA:
23.04
4f8hB-1pgsA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 8 ASP A  99
VAL A  65
PHE A 131
LEU A 107
 None
 0.99A 4f8hC-1pgsA:
undetectable
4f8hD-1pgsA:
undetectable		 4f8hC-1pgsA:
23.04
4f8hD-1pgsA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 8 ASP A  99
VAL A  65
PHE A 131
LEU A 107
 None
 0.98A 4f8hD-1pgsA:
undetectable
4f8hE-1pgsA:
undetectable		 4f8hD-1pgsA:
23.04
4f8hE-1pgsA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 8 LEU A 264
LEU A 268
SER A 271
VAL A 312
 None
 0.77A 4ik7B-1pgsA:
undetectable		 4ik7B-1pgsA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 6 LEU A 264
LEU A 268
SER A 271
VAL A 312
 None
 0.82A 5a6iA-1pgsA:
undetectable		 5a6iA-1pgsA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 6 TYR A  62
TYR A 127
GLY A  79
GLU A  77
 None
 1.12A 5emlA-1pgsA:
undetectable		 5emlA-1pgsA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		5 / 10 GLY A 203
ASP A 290
ALA A 291
ASN A 285
ASN A 284
 None
 1.17A 5x6yB-1pgsA:
undetectable		 5x6yB-1pgsA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		5 / 10 SER A 271
GLY A 270
ALA A 182
LEU A 264
LEU A 226
 None
 1.28A 6hqbA-1pgsA:
undetectable
6hqbJ-1pgsA:
undetectable		 6hqbA-1pgsA:
12.42
6hqbJ-1pgsA:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F
(Elizabethkingia
meningoseptica) 		4 / 7 TRP A 207
ARG A 210
HIS A 212
ASP A 198
 None
 1.37A 6mn4F-1pgsA:
0.0		 6mn4F-1pgsA:
17.99