SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pgu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 TRP A  95
ALA A  41
VAL A  57
 None
 0.96A 1av2C-1pguA:
undetectable
1av2D-1pguA:
undetectable		 1av2C-1pguA:
2.83
1av2D-1pguA:
2.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 SER A 171
PHE A 214
PHE A 187
GLY A 236
 None
 1.06A 1icuA-1pguA:
undetectable
1icuB-1pguA:
undetectable		 1icuA-1pguA:
17.89
1icuB-1pguA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 187
GLY A 236
SER A 171
PHE A 214
 None
 1.03A 1icuA-1pguA:
undetectable
1icuB-1pguA:
undetectable		 1icuA-1pguA:
17.89
1icuB-1pguA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 SER A 171
PHE A 214
PHE A 187
GLY A 236
 None
 1.02A 1icuC-1pguA:
0.0
1icuD-1pguA:
0.0		 1icuC-1pguA:
17.89
1icuD-1pguA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 187
GLY A 236
SER A 171
PHE A 214
 None
 1.01A 1icuC-1pguA:
0.0
1icuD-1pguA:
0.0		 1icuC-1pguA:
17.89
1icuD-1pguA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 187
GLY A 236
SER A 171
PHE A 214
 None
 1.10A 1icvA-1pguA:
0.0
1icvB-1pguA:
0.0		 1icvA-1pguA:
17.89
1icvB-1pguA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 11 SER A  64
SER A  65
GLY A  84
THR A  68
GLY A  38
 None
 1.25A 1jr1A-1pguA:
undetectable		 1jr1A-1pguA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 SER A 171
PHE A 214
PHE A 187
GLY A 236
 None
 1.16A 1kqbA-1pguA:
undetectable
1kqbB-1pguA:
undetectable		 1kqbA-1pguA:
16.18
1kqbB-1pguA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 SER A 171
PHE A 214
PHE A 187
GLY A 236
 None
 1.08A 1kqbC-1pguA:
0.0
1kqbD-1pguA:
0.0		 1kqbC-1pguA:
16.18
1kqbD-1pguA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 187
GLY A 236
SER A 171
PHE A 214
 None
 1.10A 1kqbC-1pguA:
undetectable
1kqbD-1pguA:
undetectable		 1kqbC-1pguA:
16.18
1kqbD-1pguA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 273
LEU A 259
GLY A 254
GLY A 255
THR A 269
 None
 1.15A 1likA-1pguA:
undetectable		 1likA-1pguA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 609
ILE A 351
TRP A 362
 None
 1.13A 1m8eB-1pguA:
undetectable		 1m8eB-1pguA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 609
ILE A 351
TRP A 362
 None
 1.10A 1nodB-1pguA:
undetectable		 1nodB-1pguA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 7 PRO A 118
GLY A  88
THR A  69
ILE A 122
GLY A  84
 None
 1.28A 1usqF-1pguA:
undetectable		 1usqF-1pguA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 212
TYR A 188
SER A 176
GLY A 142
ILE A 163
 None
 1.34A 2dcfA-1pguA:
0.0		 2dcfA-1pguA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ALA A  41
VAL A  57
TRP A  95
 None
 0.93A 2izqA-1pguA:
undetectable
2izqB-1pguA:
undetectable		 2izqA-1pguA:
2.83
2izqB-1pguA:
2.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 7 PRO A 118
GLY A  88
THR A  69
ILE A 122
GLY A  84
 None
 1.32A 2jkjE-1pguA:
undetectable		 2jkjE-1pguA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 7 PRO A 118
GLY A  88
THR A  69
ILE A 122
GLY A  84
 None
 1.29A 2jklE-1pguA:
undetectable		 2jklE-1pguA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 609
ILE A 351
TRP A 362
 None
 1.14A 2nodB-1pguA:
undetectable		 2nodB-1pguA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 SER A 314
LEU A 262
ILE A 276
GLY A 308
 None
 1.00A 2v0mC-1pguA:
0.0		 2v0mC-1pguA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 319
ARG A 358
GLN A 369
LEU A 317
 None
 0.97A 2xrhA-1pguA:
undetectable		 2xrhA-1pguA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 8 THR A  16
ARG A 358
LEU A  24
SER A 316
 None
 1.04A 2zw9A-1pguA:
11.5		 2zw9A-1pguA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 504
LYS A 540
ILE A 565
LEU A 598
TYR A 493
 None
 1.32A 2zzaA-1pguA:
undetectable		 2zzaA-1pguA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 212
TYR A 188
SER A 176
GLY A 142
ILE A 163
 None
 1.38A 3a65A-1pguA:
0.0		 3a65A-1pguA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 9 THR A 269
SER A 123
SER A 176
ILE A 231
GLY A 226
 None
 1.07A 3cv9A-1pguA:
undetectable		 3cv9A-1pguA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 609
ILE A 351
TRP A 362
 None
 1.06A 3e68A-1pguA:
undetectable		 3e68A-1pguA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 609
ILE A 351
TRP A 362
 None
 1.10A 3e6tB-1pguA:
undetectable		 3e6tB-1pguA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 LYS A  71
ILE A 223
PHE A 234
 None
 1.00A 3j7zS-1pguA:
0.0
3j7za-1pguA:
undetectable		 3j7zS-1pguA:
10.34
3j7za-1pguA:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 321
THR A 320
GLY A 298
ILE A 276
 None
 0.75A 3jusA-1pguA:
undetectable		 3jusA-1pguA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 321
THR A 320
GLY A 298
ILE A 276
 None
 0.75A 3jusA-1pguA:
undetectable		 3jusA-1pguA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 321
THR A 320
GLY A 298
ILE A 276
 None
 0.85A 3jusB-1pguA:
undetectable		 3jusB-1pguA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 SER A 336
ASP A 318
ASN A 299
 None
 0.98A 3lsfB-1pguA:
undetectable
3lsfE-1pguA:
undetectable		 3lsfB-1pguA:
18.20
3lsfE-1pguA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 318
ASN A 299
SER A 336
 None
 1.01A 3lsfB-1pguA:
undetectable
3lsfE-1pguA:
undetectable		 3lsfB-1pguA:
18.20
3lsfE-1pguA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 180
VAL A 186
SER A 184
THR A 178
 None
 1.07A 3tj7A-1pguA:
0.0
3tj7B-1pguA:
0.0		 3tj7A-1pguA:
15.13
3tj7B-1pguA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 180
VAL A 186
SER A 184
THR A 178
 None
 1.10A 3tj7C-1pguA:
0.0
3tj7D-1pguA:
0.1		 3tj7C-1pguA:
15.13
3tj7D-1pguA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 186
SER A 184
THR A 178
GLY A 180
 None
 1.10A 3tj7C-1pguA:
0.0
3tj7D-1pguA:
0.7		 3tj7C-1pguA:
15.13
3tj7D-1pguA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 4 ASP A  85
THR A  68
VAL A 114
SER A  83
 None
 1.43A 3wxoA-1pguA:
0.0		 3wxoA-1pguA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 4 ASP A  85
THR A  69
VAL A 114
SER A  83
 None
 1.32A 3wxoA-1pguA:
0.0		 3wxoA-1pguA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 599
LEU A 350
ILE A 607
ARG A 609
 None
 0.67A 4mghA-1pguA:
undetectable		 4mghA-1pguA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 322
LEU A 297
GLY A 298
ASP A 318
THR A  16
 None
 1.24A 4o5fA-1pguA:
undetectable
4o5fB-1pguA:
undetectable		 4o5fA-1pguA:
17.93
4o5fB-1pguA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 322
LEU A 297
GLY A 298
ASP A 318
THR A  16
 None
 1.21A 4o5fA-1pguA:
undetectable
4o5fB-1pguA:
undetectable		 4o5fA-1pguA:
17.93
4o5fB-1pguA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ILE A 231
ASP A 228
ARG A 277
 None
 0.83A 4pstA-1pguA:
undetectable		 4pstA-1pguA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 590
ALA A 579
ASN A 581
GLY A 586
ASP A 562
 None
 1.12A 4qckA-1pguA:
0.0		 4qckA-1pguA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 321
ASP A 318
ILE A 312
 None
 0.68A 4xi3D-1pguA:
undetectable		 4xi3D-1pguA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		6 / 10 LEU A 591
LEU A 345
SER A 388
LEU A 378
ASN A 380
LEU A 350
 None
 1.36A 4yiaA-1pguA:
0.0		 4yiaA-1pguA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 504
TYR A 515
PRO A 491
 None
 0.60A 4zdyA-1pguA:
undetectable		 4zdyA-1pguA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 292
TYR A 324
SER A 314
 None
 0.87A 5iktA-1pguA:
0.0		 5iktA-1pguA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 4 ASN A 589
LEU A 591
SER A 600
LEU A 350
 None
 1.37A 5kb5A-1pguA:
0.0		 5kb5A-1pguA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 GLY A 586
SER A 560
ARG A 530
GLY A 559
 None
 1.03A 5kprA-1pguA:
undetectable		 5kprA-1pguA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 8 ILE A 469
LEU A 483
ILE A 503
ILE A 496
SER A 475
 None
 1.17A 5numA-1pguA:
undetectable		 5numA-1pguA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  81
GLY A  84
SER A  73
ALA A  34
 None
 0.77A 5o96C-1pguA:
undetectable		 5o96C-1pguA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 GLY A 437
LEU A 432
HIS A 403
 None
 0.68A 5u63B-1pguA:
undetectable		 5u63B-1pguA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 256
ILE A 313
LEU A  24
HIS A  23
 None
 1.03A 5vkqB-1pguA:
undetectable
5vkqC-1pguA:
undetectable		 5vkqB-1pguA:
16.69
5vkqC-1pguA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 256
ILE A 313
LEU A  24
HIS A  23
 None
 1.02A 5vkqC-1pguA:
undetectable
5vkqD-1pguA:
undetectable		 5vkqC-1pguA:
16.69
5vkqD-1pguA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 5 HIS A  62
ALA A  41
SER A  83
GLY A  84
 None
 1.25A 5yodB-1pguA:
undetectable		 5yodB-1pguA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 169
SER A 215
SER A 218
 None
 1.14A 6gbfA-1pguA:
undetectable		 6gbfA-1pguA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1pgu ACTIN INTERACTING
PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 135
GLY A 117
GLN A 113
VAL A 114
ASP A 181
 None
 0.95A 6nj9K-1pguA:
undetectable		 6nj9K-1pguA:
21.70