SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1phj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1phj TELOMERE-BINDING
PROTEIN BETA SUBUNIT
(Sterkiella
nova) 		4 / 6 PHE B  71
PHE B  63
ASN B  79
GLN B 221
 None
 1.28A 1t9uA-1phjB:
0.0		 1t9uA-1phjB:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 1phj TELOMERE-BINDING
PROTEIN BETA SUBUNIT
(Sterkiella
nova) 		4 / 9 ILE B  88
ALA B  60
VAL B  52
CYH B  41
 None
 1.03A 2vufB-1phjB:
undetectable		 2vufB-1phjB:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1phj TELOMERE-BINDING
PROTEIN BETA SUBUNIT
(Sterkiella
nova) 		5 / 10 ILE B 215
ILE B 218
VAL B  68
PRO B 123
VAL B  43
 None
 1.29A 3elzC-1phjB:
0.0		 3elzC-1phjB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 1phj TELOMERE-BINDING
PROTEIN BETA SUBUNIT
(Sterkiella
nova) 		4 / 5 LEU B 138
ILE B 148
ALA B 114
PHE B  22
 None
 1.05A 4dc3B-1phjB:
undetectable		 4dc3B-1phjB:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 1phj TELOMERE-BINDING
PROTEIN BETA SUBUNIT
(Sterkiella
nova) 		5 / 12 ILE B  88
PHE B  14
TYR B  18
PHE B 139
LEU B  97
 None
 1.02A 4j03A-1phjB:
undetectable		 4j03A-1phjB:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1phj TELOMERE-BINDING
PROTEIN BETA SUBUNIT
(Sterkiella
nova) 		5 / 12 VAL B 100
SER B 102
THR B  19
ARG B 140
LEU B 138
 None
 1.45A 5m50B-1phjB:
undetectable		 5m50B-1phjB:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 1phj TELOMERE-BINDING
PROTEIN BETA SUBUNIT
(Sterkiella
nova) 		4 / 8 PHE B 139
PHE B  22
VAL B 100
SER B 102
 None
 1.11A 6huoC-1phjB:
undetectable
6huoD-1phjB:
undetectable		 6huoC-1phjB:
15.53
6huoD-1phjB:
18.29