SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1php'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A 166
GLY A 168
THR A  43
ILE A   6
 None
 0.87A 1gtnC-1phpA:
undetectable
1gtnD-1phpA:
undetectable		 1gtnC-1phpA:
11.62
1gtnD-1phpA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 9 GLY A 350
ASP A 352
GLY A 194
ILE A 193
ILE A 348
 ADP  A 396 (-3.6A)
MG  A 395 ( 3.0A)
None
None
None
 1.09A 1hxwA-1phpA:
undetectable		 1hxwA-1phpA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 ASP A 294
GLY A 330
VAL A 280
THR A 278
VAL A 267
 None
 0.96A 1k6cB-1phpA:
undetectable		 1k6cB-1phpA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		4 / 4 HIS A 329
ALA A 328
PHE A 322
GLY A 330
 None
 1.38A 1mjoA-1phpA:
undetectable		 1mjoA-1phpA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 11 GLU A 323
HIS A 329
ALA A 328
PHE A 322
GLY A 330
 ADP  A 396 (-2.8A)
None
None
None
None
 1.37A 1mjqI-1phpA:
undetectable
1mjqJ-1phpA:
undetectable		 1mjqI-1phpA:
17.88
1mjqJ-1phpA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 113
LEU A  80
ARG A  38
VAL A  24
ALA A  40
 None
 1.15A 1n5xA-1phpA:
0.0		 1n5xA-1phpA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 113
LEU A  80
VAL A  24
ALA A  40
ALA A  39
 None
 1.15A 1n5xA-1phpA:
0.0		 1n5xA-1phpA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 113
LEU A  80
ARG A  38
VAL A  24
ALA A  40
 None
 1.15A 1n5xB-1phpA:
0.0		 1n5xB-1phpA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 113
LEU A  80
VAL A  24
ALA A  40
ALA A  39
 None
 1.14A 1n5xB-1phpA:
0.0		 1n5xB-1phpA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 11 SER A  58
CYH A  18
LEU A  56
ILE A   6
VAL A 142
 None
 1.20A 1pkvA-1phpA:
undetectable
1pkvB-1phpA:
undetectable		 1pkvA-1phpA:
14.71
1pkvB-1phpA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 11 VAL A 142
SER A  58
CYH A  18
LEU A  56
ILE A   6
 None
 1.19A 1pkvA-1phpA:
undetectable
1pkvB-1phpA:
undetectable		 1pkvA-1phpA:
14.71
1pkvB-1phpA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		4 / 6 ALA A 390
GLU A 157
TYR A 162
ILE A 159
 None
 0.99A 1xvaA-1phpA:
undetectable
1xvaB-1phpA:
undetectable		 1xvaA-1phpA:
22.41
1xvaB-1phpA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A 350
ASP A 352
GLY A 194
ILE A 193
ILE A 348
 ADP  A 396 (-3.6A)
MG  A 395 ( 3.0A)
None
None
None
 0.97A 2ienB-1phpA:
undetectable		 2ienB-1phpA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 11 THR A  91
VAL A  88
VAL A  76
ILE A  37
ALA A  57
 None
 1.16A 2zbzA-1phpA:
0.0		 2zbzA-1phpA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_A_TESA339_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 10 ILE A 295
ASN A 316
TRP A 315
VAL A 314
VAL A 313
 None
ADP  A 396 (-3.2A)
None
None
None
 1.24A 3burA-1phpA:
0.8		 3burA-1phpA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_B_TESB340_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 10 ILE A 295
ASN A 316
TRP A 315
VAL A 314
VAL A 313
 None
ADP  A 396 (-3.2A)
None
None
None
 1.20A 3burB-1phpA:
0.6		 3burB-1phpA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 10 ASN A 316
TRP A 315
VAL A 314
VAL A 313
LEU A 338
 ADP  A 396 (-3.2A)
None
None
None
None
 1.17A 3casA-1phpA:
undetectable		 3casA-1phpA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 9 VAL A 204
LEU A 215
ILE A 217
ILE A 348
GLY A 350
 None
None
None
None
ADP  A 396 (-3.6A)
 1.11A 3cv9A-1phpA:
undetectable		 3cv9A-1phpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A 350
ASP A 352
GLY A 194
ILE A 193
ILE A 348
 ADP  A 396 (-3.6A)
MG  A 395 ( 3.0A)
None
None
None
 0.94A 3d1zB-1phpA:
undetectable		 3d1zB-1phpA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 11 GLY A 195
ASP A 200
VAL A 204
GLY A 350
ILE A 193
 ADP  A 396 (-3.3A)
None
None
ADP  A 396 (-3.6A)
None
 0.84A 3ektC-1phpA:
undetectable		 3ektC-1phpA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 ASP A 294
GLY A 330
VAL A 280
THR A 278
VAL A 267
 None
 0.93A 3el5B-1phpA:
undetectable		 3el5B-1phpA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 SER A 353
GLY A 350
GLY A 317
ASP A 213
VAL A 212
 ADP  A 396 (-2.6A)
ADP  A 396 (-3.6A)
ADP  A 396 ( 3.9A)
None
None
 0.96A 3gczA-1phpA:
2.1		 3gczA-1phpA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 GLU A 174
GLY A 147
VAL A 204
GLY A 349
ARG A  36
 None
 0.98A 3k13A-1phpA:
undetectable		 3k13A-1phpA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		4 / 7 GLY A 195
GLY A 350
PHE A 249
PHE A 225
 ADP  A 396 (-3.3A)
ADP  A 396 (-3.6A)
None
None
 0.83A 3ko0M-1phpA:
undetectable
3ko0P-1phpA:
undetectable		 3ko0M-1phpA:
13.10
3ko0P-1phpA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A 195
ASP A 200
VAL A 204
GLY A 350
ILE A 193
 ADP  A 396 (-3.3A)
None
None
ADP  A 396 (-3.6A)
None
 0.83A 3lzuB-1phpA:
undetectable		 3lzuB-1phpA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 THR A 299
ASP A 294
GLY A 330
ALA A 333
ALA A 337
 None
 0.81A 3p5nA-1phpA:
0.0		 3p5nA-1phpA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 THR A 299
ASP A 294
GLY A 330
ALA A 333
ALA A 337
 None
 0.82A 3p5nB-1phpA:
0.0		 3p5nB-1phpA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 8 GLY A 349
ASP A 352
GLY A 194
ILE A 193
THR A 331
 None
MG  A 395 ( 3.0A)
None
None
None
 1.48A 3so9A-1phpA:
undetectable		 3so9A-1phpA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 8 GLY A 194
GLY A 317
ILE A 348
LEU A 338
VAL A 314
 None
ADP  A 396 ( 3.9A)
None
None
None
 1.29A 3v1nA-1phpA:
undetectable		 3v1nA-1phpA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 10 GLY A 195
ASP A 200
VAL A 204
GLY A 350
ILE A 193
 ADP  A 396 (-3.3A)
None
None
ADP  A 396 (-3.6A)
None
 0.83A 4ll3B-1phpA:
undetectable		 4ll3B-1phpA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 10 GLY A 195
ASP A 200
VAL A 204
GLY A 350
ILE A 193
 ADP  A 396 (-3.3A)
None
None
ADP  A 396 (-3.6A)
None
 0.85A 4ll3A-1phpA:
undetectable		 4ll3A-1phpA:
15.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		8 / 12 GLY A 195
ALA A 196
GLY A 219
GLY A 220
LEU A 237
LEU A 293
GLY A 320
VAL A 321
 ADP  A 396 (-3.3A)
ADP  A 396 (-3.9A)
ADP  A 396 (-3.3A)
ADP  A 396 (-3.6A)
ADP  A 396 (-3.8A)
None
ADP  A 396 (-3.2A)
ADP  A 396 (-3.2A)
 0.46A 4o33A-1phpA:
51.9		 4o33A-1phpA:
47.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		7 / 12 GLY A 219
GLY A 220
LEU A 237
PHE A 272
LEU A 293
GLY A 320
VAL A 321
 ADP  A 396 (-3.3A)
ADP  A 396 (-3.6A)
ADP  A 396 (-3.8A)
None
None
ADP  A 396 (-3.2A)
ADP  A 396 (-3.2A)
 0.54A 4o33A-1phpA:
51.9		 4o33A-1phpA:
47.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		8 / 12 GLY A 195
ALA A 196
GLY A 219
GLY A 220
LEU A 237
PHE A 272
LEU A 293
GLY A 320
 ADP  A 396 (-3.3A)
ADP  A 396 (-3.9A)
ADP  A 396 (-3.3A)
ADP  A 396 (-3.6A)
ADP  A 396 (-3.8A)
None
None
ADP  A 396 (-3.2A)
 0.59A 4o3fA-1phpA:
50.2		 4o3fA-1phpA:
47.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		8 / 12 GLY A 195
ALA A 196
GLY A 219
GLY A 220
PHE A 272
LEU A 293
GLY A 320
VAL A 321
 ADP  A 396 (-3.3A)
ADP  A 396 (-3.9A)
ADP  A 396 (-3.3A)
ADP  A 396 (-3.6A)
None
None
ADP  A 396 (-3.2A)
ADP  A 396 (-3.2A)
 0.63A 4o3fA-1phpA:
50.2		 4o3fA-1phpA:
47.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		6 / 12 GLY A 219
GLY A 320
GLY A 330
ALA A 196
LYS A 197
GLU A 239
 ADP  A 396 (-3.3A)
ADP  A 396 (-3.2A)
None
ADP  A 396 (-3.9A)
None
None
 1.40A 5c0oG-1phpA:
3.1		 5c0oG-1phpA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		3 / 3 SER A 370
LEU A 338
MET A 366
 None
 0.76A 5ikrB-1phpA:
undetectable		 5ikrB-1phpA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		4 / 5 GLU A 174
GLY A 349
SER A 376
GLY A 374
 None
 1.07A 5kprA-1phpA:
undetectable		 5kprA-1phpA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		4 / 4 GLY A 372
ALA A 148
MET A 171
THR A 156
 None
 1.23A 5n0sB-1phpA:
1.5		 5n0sB-1phpA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A 195
ASP A 200
VAL A 204
GLY A 350
ILE A 193
 ADP  A 396 (-3.3A)
None
None
ADP  A 396 (-3.6A)
None
 0.86A 5t2zB-1phpA:
undetectable		 5t2zB-1phpA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		5 / 10 ALA A  77
LEU A 113
VAL A  88
ILE A  48
ALA A  40
 None
 1.25A 6h1lA-1phpA:
undetectable		 6h1lA-1phpA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1php 3-PHOSPHOGLYCERATE
KINASE
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 308
GLU A 309
ASP A 305
GLU A 301
 None
 1.50A 6mn5D-1phpA:
0.0		 6mn5D-1phpA:
13.19