SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		5 / 12 TRP A  37
TRP A  13
GLY A  42
VAL A  24
ALA A 101
 None
 1.22A 2kceA-1pjzA:
undetectable		 2kceA-1pjzA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 TRP A 166
GLN A 155
TRP A  13
 None
 1.01A 2vqyA-1pjzA:
2.4		 2vqyA-1pjzA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 LEU A  16
TYR A  12
GLN A  11
 None
 0.63A 2wekA-1pjzA:
5.6		 2wekA-1pjzA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		5 / 10 ALA A 107
LEU A 145
LEU A 188
LEU A 139
LEU A 146
 None
 1.16A 2xn6A-1pjzA:
undetectable
2xn6B-1pjzA:
undetectable		 2xn6A-1pjzA:
19.89
2xn6B-1pjzA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		5 / 10 GLY A 172
THR A 138
VAL A 171
LEU A 139
LEU A 135
 None
 1.32A 4yb6C-1pjzA:
undetectable
4yb6F-1pjzA:
undetectable		 4yb6C-1pjzA:
20.97
4yb6F-1pjzA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		5 / 10 LEU A 139
LEU A 135
GLY A 172
THR A 138
VAL A 171
 None
 1.29A 4yb6A-1pjzA:
undetectable
4yb6D-1pjzA:
undetectable		 4yb6A-1pjzA:
20.97
4yb6D-1pjzA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		5 / 10 LEU A 139
LEU A 135
GLY A 172
THR A 138
VAL A 171
 None
 1.35A 4yb6D-1pjzA:
undetectable
4yb6E-1pjzA:
undetectable		 4yb6D-1pjzA:
20.97
4yb6E-1pjzA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.54A 5qgjA-1pjzA:
undetectable		 5qgjA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.62A 5qglA-1pjzA:
undetectable		 5qglA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.55A 5qgmA-1pjzA:
undetectable		 5qgmA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qgnA-1pjzA:
0.0		 5qgnA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.56A 5qguA-1pjzA:
undetectable		 5qguA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qgvA-1pjzA:
undetectable		 5qgvA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.56A 5qgwA-1pjzA:
undetectable		 5qgwA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qgxA-1pjzA:
undetectable		 5qgxA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.58A 5qgyA-1pjzA:
undetectable		 5qgyA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qgzA-1pjzA:
0.0		 5qgzA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qh0A-1pjzA:
undetectable		 5qh0A-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.58A 5qh1A-1pjzA:
undetectable		 5qh1A-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.58A 5qh2A-1pjzA:
0.0		 5qh2A-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qh3A-1pjzA:
0.0		 5qh3A-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qh4A-1pjzA:
undetectable		 5qh4A-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qh5A-1pjzA:
0.0		 5qh5A-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.54A 5qh6A-1pjzA:
0.0		 5qh6A-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qh7A-1pjzA:
0.0		 5qh7A-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.55A 5qh9A-1pjzA:
undetectable		 5qh9A-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qhaA-1pjzA:
undetectable		 5qhaA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.56A 5qhcA-1pjzA:
undetectable		 5qhcA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.57A 5qheA-1pjzA:
undetectable		 5qheA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.55A 5qhfA-1pjzA:
undetectable		 5qhfA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.59A 5qhgA-1pjzA:
undetectable		 5qhgA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		3 / 3 VAL A 195
VAL A 171
GLN A  11
 None
 0.56A 5qhhA-1pjzA:
undetectable		 5qhhA-1pjzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1pjz THIOPURINE
S-METHYLTRANSFERASE
(Pseudomonas
syringae) 		4 / 4 LEU A 184
GLY A 183
SER A 180
SER A 179
 None
 1.18A 5uunB-1pjzA:
undetectable		 5uunB-1pjzA:
23.29