SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pku'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1pku NUCLEOSIDE
DIPHOSPHATE KINASE I
(Oryza
sativa) 		4 / 7 ALA A 139
GLU A 140
LEU A 138
VAL A  77
 None
 0.59A 1hk2A-1pkuA:
undetectable		 1hk2A-1pkuA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 1pku NUCLEOSIDE
DIPHOSPHATE KINASE I
(Oryza
sativa) 		4 / 5 VAL A 123
GLY A 126
VAL A  84
TRP A  78
 None
 1.25A 1tkqB-1pkuA:
undetectable		 1tkqB-1pkuA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 1pku NUCLEOSIDE
DIPHOSPHATE KINASE I
(Oryza
sativa) 		5 / 12 ARG A  18
LEU A  20
ILE A  90
GLY A 102
VAL A 116
 None
 0.96A 3nu3A-1pkuA:
undetectable		 3nu3A-1pkuA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1pku NUCLEOSIDE
DIPHOSPHATE KINASE I
(Oryza
sativa) 		4 / 5 PHE A  28
ILE A 104
GLY A  87
ILE A  24
 None
 0.81A 5dzkB-1pkuA:
undetectable
5dzkI-1pkuA:
undetectable
5dzkW-1pkuA:
undetectable		 5dzkB-1pkuA:
21.80
5dzkI-1pkuA:
22.49
5dzkW-1pkuA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 1pku NUCLEOSIDE
DIPHOSPHATE KINASE I
(Oryza
sativa) 		4 / 4 GLN A  49
VAL A  65
GLU A  66
ILE A  69
 None
 1.47A 5jncA-1pkuA:
0.0		 5jncA-1pkuA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1pku NUCLEOSIDE
DIPHOSPHATE KINASE I
(Oryza
sativa) 		3 / 3 GLY A  19
ASP A  23
ILE A 104
 None
 0.58A 6dgxB-1pkuA:
undetectable		 6dgxB-1pkuA:
17.65