SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1plb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1plb	PLASTOCYANIN (Petroselinum crispum)	4 / 4	HIS A 37 CYH A 82 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) CU A 100 (-3.3A) CU A 100 (-3.1A)	0.41A	1oe1A-1plbA: undetectable	1oe1A-1plbA: 15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1plb	PLASTOCYANIN (Petroselinum crispum)	5 / 5	HIS A 37 CYH A 82 PRO A 84 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) None CU A 100 (-3.3A) CU A 100 (-3.1A)	0.93A	1oe2A-1plbA: 5.3	1oe2A-1plbA: 15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1plb	PLASTOCYANIN (Petroselinum crispum)	4 / 4	HIS A 37 CYH A 82 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) CU A 100 (-3.3A) CU A 100 (-3.1A)	0.42A	1oe3A-1plbA: undetectable	1oe3A-1plbA: 15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1plb	PLASTOCYANIN (Petroselinum crispum)	4 / 4	HIS A 37 CYH A 82 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) CU A 100 (-3.3A) CU A 100 (-3.1A)	0.60A	2fqdA-1plbA: undetectable	2fqdA-1plbA: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1plb	PLASTOCYANIN (Petroselinum crispum)	4 / 4	HIS A 37 CYH A 82 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) CU A 100 (-3.3A) CU A 100 (-3.1A)	0.58A	2fqeA-1plbA: undetectable	2fqeA-1plbA: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQF_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1plb	PLASTOCYANIN (Petroselinum crispum)	4 / 4	HIS A 37 CYH A 82 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) CU A 100 (-3.3A) CU A 100 (-3.1A)	0.57A	2fqfA-1plbA: undetectable	2fqfA-1plbA: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1plb	PLASTOCYANIN (Petroselinum crispum)	4 / 4	HIS A 37 CYH A 82 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) CU A 100 (-3.3A) CU A 100 (-3.1A)	0.57A	2fqgA-1plbA: undetectable	2fqgA-1plbA: 11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1337_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1plb	PLASTOCYANIN (Petroselinum crispum)	4 / 4	HIS A 37 CYH A 82 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) CU A 100 (-3.3A) CU A 100 (-3.1A)	0.40A	2xxgA-1plbA: 5.5	2xxgA-1plbA: 14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1plb	PLASTOCYANIN (Petroselinum crispum)	5 / 5	HIS A 37 CYH A 82 PRO A 84 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) None CU A 100 (-3.3A) CU A 100 (-3.1A)	0.98A	2xxgC-1plbA: 5.5	2xxgC-1plbA: 14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EF3_A_CUA1001_0 (BLUE COPPER OXIDASE CUEO)	1plb	PLASTOCYANIN (Petroselinum crispum)	4 / 4	HIS A 37 CYH A 82 HIS A 85 MET A 90	CU A 100 ( 3.2A) CU A 100 (-2.0A) CU A 100 (-3.3A) CU A 100 (-3.1A)	0.54A	4ef3A-1plbA: undetectable	4ef3A-1plbA: 10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GWZ_D_010D6_0 (N-[(5-METHYLISOXAZOL -3-YL)CARBONYL]ALANY L-L-VALYL-N~1~-((1R, 2Z)-4-(BENZYLOXY)-4- OXO-1-{[(3R)-2-OXOPY RROLIDIN-3-YL]METHYL }BUT-2-ENYL)-L-LEUCI NAMIDE PEDV MAIN PROTEASE)	1plb	PLASTOCYANIN (Petroselinum crispum)	3 / 3	MET A 90 HIS A 37 GLY A 11	CU A 100 (-3.1A) CU A 100 ( 3.2A) None	0.45A	5gwzB-1plbA: undetectable	5gwzB-1plbA: 16.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE1_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1plb","PLASTOCYANIN","Petroselinum crispum",4,"HIS A  37;CYH A  82;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A); CU A 100 (-3.3A); CU A 100 (-3.1A)","0.41A","1oe1A-1plbA:undetectable","1oe1A-1plbA:15.26"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1plb","PLASTOCYANIN","Petroselinum crispum",5,"HIS A  37;CYH A  82;PRO A  84;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A);None; CU A 100 (-3.3A); CU A 100 (-3.1A)","0.93A","1oe2A-1plbA:5.3","1oe2A-1plbA:15.26"],["1OE3_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1plb","PLASTOCYANIN","Petroselinum crispum",4,"HIS A  37;CYH A  82;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A); CU A 100 (-3.3A); CU A 100 (-3.1A)","0.42A","1oe3A-1plbA:undetectable","1oe3A-1plbA:15.26"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1plb","PLASTOCYANIN","Petroselinum crispum",4,"HIS A  37;CYH A  82;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A); CU A 100 (-3.3A); CU A 100 (-3.1A)","0.60A","2fqdA-1plbA:undetectable","2fqdA-1plbA:11.52"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1plb","PLASTOCYANIN","Petroselinum crispum",4,"HIS A  37;CYH A  82;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A); CU A 100 (-3.3A); CU A 100 (-3.1A)","0.58A","2fqeA-1plbA:undetectable","2fqeA-1plbA:11.52"],["2FQF_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1plb","PLASTOCYANIN","Petroselinum crispum",4,"HIS A  37;CYH A  82;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A); CU A 100 (-3.3A); CU A 100 (-3.1A)","0.57A","2fqfA-1plbA:undetectable","2fqfA-1plbA:11.52"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1plb","PLASTOCYANIN","Petroselinum crispum",4,"HIS A  37;CYH A  82;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A); CU A 100 (-3.3A); CU A 100 (-3.1A)","0.57A","2fqgA-1plbA:undetectable","2fqgA-1plbA:11.52"],["2XXG_A_CUA1337_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1plb","PLASTOCYANIN","Petroselinum crispum",4,"HIS A  37;CYH A  82;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A); CU A 100 (-3.3A); CU A 100 (-3.1A)","0.40A","2xxgA-1plbA:5.5","2xxgA-1plbA:14.60"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1plb","PLASTOCYANIN","Petroselinum crispum",5,"HIS A  37;CYH A  82;PRO A  84;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A);None; CU A 100 (-3.3A); CU A 100 (-3.1A)","0.98A","2xxgC-1plbA:5.5","2xxgC-1plbA:14.60"],["4EF3_A_CUA1001_0","BLUE COPPER OXIDASE CUEO","1plb","PLASTOCYANIN","Petroselinum crispum",4,"HIS A  37;CYH A  82;HIS A  85;MET A  90"," CU A 100 ( 3.2A); CU A 100 (-2.0A); CU A 100 (-3.3A); CU A 100 (-3.1A)","0.54A","4ef3A-1plbA:undetectable","4ef3A-1plbA:10.82"],["5GWZ_D_010D6_0","N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE;PEDV MAIN PROTEASE","1plb","PLASTOCYANIN","Petroselinum crispum",3,"MET A  90;HIS A  37;GLY A  11"," CU A 100 (-3.1A); CU A 100 ( 3.2A);None","0.45A","5gwzB-1plbA:undetectable","5gwzB-1plbA:16.23"]]