SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pm2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 6 LEU A 193
MET A 198
MET A 261
LEU A 249
 None
 1.23A 1errB-1pm2A:
2.6		 1errB-1pm2A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 12 LEU A 197
ASN A 201
LEU A 104
MET A  17
LEU A 251
 None
 1.36A 1nhzA-1pm2A:
undetectable		 1nhzA-1pm2A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 6 LEU A  83
GLU A 115
TRP A 111
THR A 245
 None
MN  A 502 ( 2.3A)
None
None
 1.40A 1qvuA-1pm2A:
0.1		 1qvuA-1pm2A:
19.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		9 / 11 GLU A 115
HIS A 118
LEU A 203
GLU A 204
ARG A 207
TYR A 209
PHE A 212
ILE A 234
GLU A 238
 MN  A 502 ( 2.3A)
MN  A 501 (-3.1A)
None
MN  A 502 (-2.2A)
None
None
None
None
MN  A 502 ( 2.5A)
 0.49A 1rnrA-1pm2A:
54.0		 1rnrA-1pm2A:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		8 / 11 GLU A 115
HIS A 118
LEU A 203
GLU A 204
ARG A 207
TYR A 209
SER A 211
GLU A 238
 MN  A 502 ( 2.3A)
MN  A 501 (-3.1A)
None
MN  A 502 (-2.2A)
None
None
None
MN  A 502 ( 2.5A)
 0.73A 1rnrA-1pm2A:
54.0		 1rnrA-1pm2A:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		6 / 11 GLU A 238
HIS A 241
LEU A  83
GLU A  84
SER A  90
GLU A 115
 MN  A 502 ( 2.5A)
MN  A 502 (-3.1A)
None
MN  A 501 (-1.9A)
None
MN  A 502 ( 2.3A)
 1.19A 1rnrA-1pm2A:
54.0		 1rnrA-1pm2A:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		11 / 12 GLU A 115
HIS A 118
TYR A 122
LEU A 203
GLU A 204
ARG A 207
TYR A 209
SER A 211
PHE A 212
ILE A 234
GLU A 238
 MN  A 502 ( 2.3A)
MN  A 501 (-3.1A)
None
None
MN  A 502 (-2.2A)
None
None
None
None
None
MN  A 502 ( 2.5A)
 0.50A 1rnrB-1pm2A:
53.0		 1rnrB-1pm2A:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 12 GLU A 238
HIS A 241
LEU A  83
GLU A  84
GLU A 115
 MN  A 502 ( 2.5A)
MN  A 502 (-3.1A)
None
MN  A 501 (-1.9A)
MN  A 502 ( 2.3A)
 0.92A 1rnrB-1pm2A:
53.0		 1rnrB-1pm2A:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 12 GLU A 238
LEU A  83
GLU A  84
SER A  90
GLU A 115
 MN  A 502 ( 2.5A)
None
MN  A 501 (-1.9A)
None
MN  A 502 ( 2.3A)
 1.37A 1rnrB-1pm2A:
53.0		 1rnrB-1pm2A:
99.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 8 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.27A 1v55N-1pm2A:
undetectable
1v55W-1pm2A:
undetectable		 1v55N-1pm2A:
19.19
1v55W-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 8 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.27A 2einA-1pm2A:
1.8
2einJ-1pm2A:
undetectable		 2einA-1pm2A:
19.19
2einJ-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 12 GLY A  20
THR A 164
MET A 261
LEU A 252
LEU A 249
 None
 0.94A 2hw2A-1pm2A:
undetectable		 2hw2A-1pm2A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 5 ILE A 161
PRO A  97
VAL A 319
PHE A  18
 None
 0.84A 2ygnA-1pm2A:
undetectable		 2ygnA-1pm2A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 8 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.20A 3abkA-1pm2A:
1.6
3abkJ-1pm2A:
undetectable		 3abkA-1pm2A:
19.19
3abkJ-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 8 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.27A 3abmN-1pm2A:
undetectable
3abmW-1pm2A:
undetectable		 3abmN-1pm2A:
19.19
3abmW-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 7 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.27A 3ag2N-1pm2A:
0.8
3ag2W-1pm2A:
undetectable		 3ag2N-1pm2A:
19.19
3ag2W-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 7 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.27A 3ag3A-1pm2A:
0.8
3ag3J-1pm2A:
0.0		 3ag3A-1pm2A:
19.19
3ag3J-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 7 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.27A 3ag4N-1pm2A:
0.8
3ag4W-1pm2A:
undetectable		 3ag4N-1pm2A:
19.19
3ag4W-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 8 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.24A 3asoN-1pm2A:
undetectable
3asoW-1pm2A:
undetectable		 3asoN-1pm2A:
19.19
3asoW-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 8 TYR A 122
ILE A 125
ILE A 126
ILE A  74
 None
 0.67A 3p4wC-1pm2A:
2.2		 3p4wC-1pm2A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 7 PHE A  36
ASP A 257
ILE A  99
VAL A 108
 None
 0.83A 3p6hA-1pm2A:
undetectable		 3p6hA-1pm2A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 6 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.33A 3wg7A-1pm2A:
0.8
3wg7J-1pm2A:
undetectable		 3wg7A-1pm2A:
19.19
3wg7J-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 12 GLU A 159
ASP A 158
ILE A  86
LEU A  82
GLY A 152
 None
 1.16A 4djfB-1pm2A:
undetectable		 4djfB-1pm2A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 8 LEU A  82
GLU A 204
GLU A 115
ALA A 112
 None
MN  A 502 (-2.2A)
MN  A 502 ( 2.3A)
None
 0.89A 4rjdA-1pm2A:
0.0
4rjdB-1pm2A:
0.0		 4rjdA-1pm2A:
12.83
4rjdB-1pm2A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 7 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.46A 5b1aA-1pm2A:
0.8
5b1aJ-1pm2A:
undetectable		 5b1aA-1pm2A:
19.19
5b1aJ-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 6 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.29A 5b1aN-1pm2A:
0.8
5b1aW-1pm2A:
0.0		 5b1aN-1pm2A:
19.19
5b1aW-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 7 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.44A 5b3sA-1pm2A:
undetectable
5b3sJ-1pm2A:
undetectable		 5b3sA-1pm2A:
19.19
5b3sJ-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EUM_B_ACTB603_0
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 4 ALA A 205
ASN A 201
ARG A 315
ILE A 206
 None
 1.43A 5eumB-1pm2A:
0.0		 5eumB-1pm2A:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 7 TYR A 122
ILE A 125
ILE A 126
ILE A  74
 None
 0.63A 5murB-1pm2A:
2.7		 5murB-1pm2A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 7 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.31A 5xdqA-1pm2A:
0.8
5xdqJ-1pm2A:
undetectable		 5xdqA-1pm2A:
19.19
5xdqJ-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 7 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.24A 5xdqN-1pm2A:
0.8
5xdqW-1pm2A:
undetectable		 5xdqN-1pm2A:
19.19
5xdqW-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 5 ILE A 335
TYR A 310
ARG A 328
THR A 312
 None
None
HG  A 614 ( 4.9A)
None
 1.21A 5z84N-1pm2A:
0.8
5z84W-1pm2A:
0.0		 5z84N-1pm2A:
19.19
5z84W-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 7 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.49A 5zcpA-1pm2A:
1.6
5zcpJ-1pm2A:
undetectable		 5zcpA-1pm2A:
19.19
5zcpJ-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 8 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.21A 5zcpN-1pm2A:
undetectable
5zcpW-1pm2A:
undetectable		 5zcpN-1pm2A:
19.19
5zcpW-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 7 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.45A 5zcqA-1pm2A:
1.0
5zcqJ-1pm2A:
undetectable		 5zcqA-1pm2A:
19.19
5zcqJ-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 10 THR A  81
SER A 121
ILE A 125
ILE A 231
ILE A 234
 None
 0.51A 6ebpD-1pm2A:
29.0		 6ebpD-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 SER A 121
ILE A 125
PHE A 212
ILE A 231
ILE A 234
 None
 0.67A 6ebzA-1pm2A:
28.9		 6ebzA-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 THR A  81
SER A 121
ILE A 125
ILE A 231
ILE A 234
 None
 0.49A 6ebzA-1pm2A:
28.9		 6ebzA-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 SER A 121
ILE A 125
PHE A 212
ILE A 231
ILE A 234
 None
 0.70A 6ebzB-1pm2A:
29.1		 6ebzB-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 THR A  81
SER A 121
ILE A 125
ILE A 231
ILE A 234
 None
 0.52A 6ebzB-1pm2A:
29.1		 6ebzB-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 SER A 121
ILE A 125
PHE A 212
ILE A 231
ILE A 234
 None
 0.95A 6ebzC-1pm2A:
28.9		 6ebzC-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 THR A  81
SER A 121
ILE A 125
ILE A 231
ILE A 234
 None
 0.81A 6ebzC-1pm2A:
28.9		 6ebzC-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 SER A 121
ILE A 125
PHE A 212
ILE A 231
ILE A 234
 None
 0.71A 6ebzD-1pm2A:
29.0		 6ebzD-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 THR A  81
SER A 121
ILE A 125
ILE A 231
ILE A 234
 None
 0.50A 6ebzD-1pm2A:
29.0		 6ebzD-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 6 PHE A 276
LEU A 275
ALA A 202
ASN A 250
 None
 0.91A 6f88A-1pm2A:
undetectable		 6f88A-1pm2A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		6 / 11 THR A  81
SER A 121
ILE A 125
PHE A 212
ILE A 231
ILE A 234
 None
 0.82A 6gp2A-1pm2A:
29.1		 6gp2A-1pm2A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 THR A  81
SER A 121
ILE A 125
ILE A 231
ILE A 234
 None
 0.55A 6gp2B-1pm2A:
29.2		 6gp2B-1pm2A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 11 THR A  81
SER A 121
PHE A 212
ILE A 231
ILE A 234
 None
 0.84A 6gp2B-1pm2A:
29.2		 6gp2B-1pm2A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		5 / 6 ILE A 335
LEU A 339
TYR A 310
ARG A 328
THR A 312
 None
None
None
HG  A 614 ( 4.9A)
None
 1.44A 6nmfN-1pm2A:
undetectable
6nmfW-1pm2A:
undetectable		 6nmfN-1pm2A:
19.19
6nmfW-1pm2A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN
(Escherichia
coli) 		4 / 5 ILE A 335
LEU A 339
ARG A 328
THR A 312
 None
None
HG  A 614 ( 4.9A)
None
 0.90A 6nmpN-1pm2A:
0.7
6nmpW-1pm2A:
0.0		 6nmpN-1pm2A:
19.19
6nmpW-1pm2A:
11.21