SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pmj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 ILE X 173
ASP X  61
GLY X 164
PHE X 103
 None
 0.88A 1rtsB-1pmjX:
undetectable		 1rtsB-1pmjX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 ILE X 173
ASP X  61
GLY X 164
PHE X 103
 None
 0.88A 2tsrA-1pmjX:
undetectable		 2tsrA-1pmjX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 ILE X 173
ASP X  61
GLY X 164
PHE X 103
 None
 0.95A 2tsrB-1pmjX:
undetectable		 2tsrB-1pmjX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 TYR X 105
VAL X  16
VAL X 178
ARG X  49
 None
 1.05A 3pyyA-1pmjX:
undetectable		 3pyyA-1pmjX:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 GLY X 127
ALA X 126
ILE X 122
ILE X 173
ILE X  91
 EDO  X 401 (-3.4A)
EDO  X 401 ( 4.2A)
None
None
None
 1.00A 4dt8A-1pmjX:
undetectable		 4dt8A-1pmjX:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 10 GLY X 127
ALA X 126
ILE X 122
ILE X 173
ILE X  91
 EDO  X 401 (-3.4A)
EDO  X 401 ( 4.2A)
None
None
None
 1.05A 4dt8B-1pmjX:
undetectable		 4dt8B-1pmjX:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 ILE X 173
ASP X  61
GLY X 164
PHE X 103
 None
 0.89A 4iqqA-1pmjX:
undetectable		 4iqqA-1pmjX:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 ILE X 173
ASP X  61
GLY X 164
PHE X 103
 None
 0.89A 4iqqB-1pmjX:
undetectable		 4iqqB-1pmjX:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 ILE X 173
ASP X  61
GLY X 164
PHE X 103
 None
 0.89A 4iqqD-1pmjX:
undetectable		 4iqqD-1pmjX:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 ILE X 173
ASP X  61
GLY X 164
PHE X 103
 None
 0.84A 5h3aA-1pmjX:
undetectable		 5h3aA-1pmjX:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 ILE X 173
ASP X  61
GLY X 164
PHE X 103
 None
 0.82A 5h3aB-1pmjX:
undetectable		 5h3aB-1pmjX:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 ILE X 173
ASP X  61
GLY X 164
PHE X 103
 None
 0.90A 5nooD-1pmjX:
undetectable		 5nooD-1pmjX:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 5 LEU X  50
PHE X 162
LEU X  65
PHE X  19
 None
 1.04A 5x19C-1pmjX:
undetectable
5x19J-1pmjX:
undetectable		 5x19C-1pmjX:
19.08
5x19J-1pmjX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1pmj BETA-1,4-MANNANASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 ILE X 122
LEU X   9
PHE X 103
PHE X 160
LEU X 158
 None
 1.25A 6a93A-1pmjX:
undetectable		 6a93A-1pmjX:
18.95