SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) CU A 124 (-3.1A) CU A 124 (-2.6A)	0.33A	1oe1A-1pmyA: 3.6	1oe1A-1pmyA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	5 / 5	HIS A 40 CYH A 78 PRO A 80 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) None CU A 124 (-3.1A) CU A 124 (-2.6A)	0.73A	1oe2A-1pmyA: 5.3	1oe2A-1pmyA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 5	HIS A 40 PRO A 80 HIS A 81 MET A 16	CU A 124 (-3.1A) None CU A 124 (-3.1A) CU A 124 ( 4.9A)	1.48A	1oe2A-1pmyA: 5.3	1oe2A-1pmyA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) CU A 124 (-3.1A) CU A 124 (-2.6A)	0.36A	1oe3A-1pmyA: undetectable	1oe3A-1pmyA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) CU A 124 (-3.1A) CU A 124 (-2.6A)	0.53A	2fqdA-1pmyA: undetectable	2fqdA-1pmyA: 13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) CU A 124 (-3.1A) CU A 124 (-2.6A)	0.48A	2fqeA-1pmyA: undetectable	2fqeA-1pmyA: 13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQF_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) CU A 124 (-3.1A) CU A 124 (-2.6A)	0.46A	2fqfA-1pmyA: undetectable	2fqfA-1pmyA: 13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) CU A 124 (-3.1A) CU A 124 (-2.6A)	0.46A	2fqgA-1pmyA: undetectable	2fqgA-1pmyA: 13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1337_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) CU A 124 (-3.1A) CU A 124 (-2.6A)	0.36A	2xxgA-1pmyA: 5.4	2xxgA-1pmyA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	5 / 5	HIS A 40 CYH A 78 PRO A 80 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) None CU A 124 (-3.1A) CU A 124 (-2.6A)	0.78A	2xxgC-1pmyA: 5.3	2xxgC-1pmyA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z0A_A_GLYA73_0 (NONSTRUCTURAL PROTEIN 1)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 5	ALA A 120 GLN A 121 ILE A 122 ARG A 24	None	1.41A	2z0aA-1pmyA: undetectable	2z0aA-1pmyA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EF3_A_CUA1001_0 (BLUE COPPER OXIDASE CUEO)	1pmy	PSEUDOAZURIN (Methylobacterium extorquens)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A 124 (-3.1A) CU A 124 (-2.1A) CU A 124 (-3.1A) CU A 124 (-2.6A)	0.43A	4ef3A-1pmyA: undetectable	4ef3A-1pmyA: 13.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE1_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A); CU A 124 (-3.1A); CU A 124 (-2.6A)","0.33A","1oe1A-1pmyA:3.6","1oe1A-1pmyA:17.82"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",5,"HIS A  40;CYH A  78;PRO A  80;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A);None; CU A 124 (-3.1A); CU A 124 (-2.6A)","0.73A","1oe2A-1pmyA:5.3","1oe2A-1pmyA:17.82"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"HIS A  40;PRO A  80;HIS A  81;MET A  16"," CU A 124 (-3.1A);None; CU A 124 (-3.1A); CU A 124 ( 4.9A)","1.48A","1oe2A-1pmyA:5.3","1oe2A-1pmyA:17.82"],["1OE3_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A); CU A 124 (-3.1A); CU A 124 (-2.6A)","0.36A","1oe3A-1pmyA:undetectable","1oe3A-1pmyA:17.82"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A); CU A 124 (-3.1A); CU A 124 (-2.6A)","0.53A","2fqdA-1pmyA:undetectable","2fqdA-1pmyA:13.29"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A); CU A 124 (-3.1A); CU A 124 (-2.6A)","0.48A","2fqeA-1pmyA:undetectable","2fqeA-1pmyA:13.29"],["2FQF_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A); CU A 124 (-3.1A); CU A 124 (-2.6A)","0.46A","2fqfA-1pmyA:undetectable","2fqfA-1pmyA:13.29"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A); CU A 124 (-3.1A); CU A 124 (-2.6A)","0.46A","2fqgA-1pmyA:undetectable","2fqgA-1pmyA:13.29"],["2XXG_A_CUA1337_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A); CU A 124 (-3.1A); CU A 124 (-2.6A)","0.36A","2xxgA-1pmyA:5.4","2xxgA-1pmyA:17.82"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",5,"HIS A  40;CYH A  78;PRO A  80;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A);None; CU A 124 (-3.1A); CU A 124 (-2.6A)","0.78A","2xxgC-1pmyA:5.3","2xxgC-1pmyA:17.82"],["2Z0A_A_GLYA73_0","NONSTRUCTURAL PROTEIN 1","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"ALA A 120;GLN A 121;ILE A 122;ARG A  24","None","1.41A","2z0aA-1pmyA:undetectable","2z0aA-1pmyA:19.35"],["4EF3_A_CUA1001_0","BLUE COPPER OXIDASE CUEO","1pmy","PSEUDOAZURIN","Methylobacterium extorquens",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A 124 (-3.1A); CU A 124 (-2.1A); CU A 124 (-3.1A); CU A 124 (-2.6A)","0.43A","4ef3A-1pmyA:undetectable","4ef3A-1pmyA:13.47"]]