SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1poj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 LEU A 227
LEU A 103
LEU A 133
GLY A 160
PHE A 339
 None
KCX  A 162 ( 4.2A)
KCX  A 162 ( 4.2A)
None
None
 1.24A 1d4fA-1pojA:
2.1		 1d4fA-1pojA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 6 HIS A  68
HIS A  70
HIS A 201
HIS A 230
ASP A 285
 ZN  A 601 (-3.6A)
ZN  A 601 ( 3.6A)
ZN  A 602 ( 2.8A)
ZN  A 602 ( 3.5A)
AE1  A 401 ( 2.6A)
 0.86A 1fweC-1pojA:
21.8		 1fweC-1pojA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 GLY A 102
VAL A 100
ASP A  66
ALA A 136
GLY A 286
 None
 0.98A 1kiaB-1pojA:
undetectable		 1kiaB-1pojA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 GLY A 102
VAL A 100
ASP A  66
ALA A 136
GLY A 286
 None
 0.98A 1kiaC-1pojA:
undetectable		 1kiaC-1pojA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 8 ASP A 204
ASP A 167
ASP A 285
THR A 254
 None
None
AE1  A 401 ( 2.6A)
None
 0.83A 1m4iA-1pojA:
undetectable		 1m4iA-1pojA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 THR A 254
SER A 256
SER A 283
VAL A  87
HIS A  70
 None
None
None
None
ZN  A 601 ( 3.6A)
 1.39A 1q23D-1pojA:
undetectable
1q23E-1pojA:
undetectable		 1q23D-1pojA:
18.73
1q23E-1pojA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 8 GLY A 193
GLY A 189
GLY A 188
LEU A 190
 None
 0.66A 1qzzA-1pojA:
undetectable		 1qzzA-1pojA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 8 THR A  82
GLY A  75
ARG A 169
ILE A 302
PRO A 291
 None
AE1  A 401 (-3.5A)
AE1  A 401 (-3.3A)
None
AE1  A 401 (-4.4A)
 1.48A 1rxcB-1pojA:
undetectable		 1rxcB-1pojA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 8 THR A  82
GLY A  75
ARG A 169
ILE A 302
PRO A 291
 None
AE1  A 401 (-3.5A)
AE1  A 401 (-3.3A)
None
AE1  A 401 (-4.4A)
 1.46A 1rxcE-1pojA:
undetectable		 1rxcE-1pojA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 8 THR A  82
GLY A  75
ARG A 169
ILE A 302
PRO A 291
 None
AE1  A 401 (-3.5A)
AE1  A 401 (-3.3A)
None
AE1  A 401 (-4.4A)
 1.48A 1rxcK-1pojA:
undetectable		 1rxcK-1pojA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 LEU A 227
ASP A 252
THR A 254
LEU A 103
GLY A 102
 None
None
None
KCX  A 162 ( 4.2A)
None
 1.33A 1v8bA-1pojA:
undetectable		 1v8bA-1pojA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 HIS A  70
THR A  84
LEU A 103
GLY A 102
PHE A 307
 ZN  A 601 ( 3.6A)
None
KCX  A 162 ( 4.2A)
None
None
 1.48A 1v8bB-1pojA:
undetectable		 1v8bB-1pojA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 LEU A 227
ASP A 252
THR A 254
LEU A 103
GLY A 102
 None
None
None
KCX  A 162 ( 4.2A)
None
 1.32A 1v8bB-1pojA:
undetectable		 1v8bB-1pojA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 HIS A  68
ASP A 285
LEU A 103
GLY A 102
PHE A 307
 ZN  A 601 (-3.6A)
AE1  A 401 ( 2.6A)
KCX  A 162 ( 4.2A)
None
None
 1.25A 1v8bD-1pojA:
undetectable		 1v8bD-1pojA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 LEU A 227
ASP A 252
THR A 254
LEU A 103
GLY A 102
 None
None
None
KCX  A 162 ( 4.2A)
None
 1.30A 1v8bD-1pojA:
undetectable		 1v8bD-1pojA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 THR A 106
GLY A 288
GLY A  74
GLY A  76
VAL A  87
 AE1  A 401 (-3.1A)
AE1  A 401 ( 4.1A)
AE1  A 401 (-3.4A)
None
None
 0.94A 2b25A-1pojA:
undetectable		 2b25A-1pojA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 ASN A 232
PHE A 238
ILE A 253
SER A 255
LEU A 317
 None
 1.12A 2ft9A-1pojA:
0.2		 2ft9A-1pojA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 6 ILE A  65
SER A  99
ARG A 157
ILE A 159
 None
 1.17A 2q72A-1pojA:
undetectable		 2q72A-1pojA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 ASP A 252
LEU A 103
LEU A 133
GLY A 160
PHE A 339
 None
KCX  A 162 ( 4.2A)
KCX  A 162 ( 4.2A)
None
None
 1.41A 2zj0B-1pojA:
undetectable		 2zj0B-1pojA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 11 ILE A 223
LEU A 209
LEU A 216
ILE A 212
THR A 198
 None
 1.40A 3a50B-1pojA:
undetectable		 3a50B-1pojA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		3 / 3 GLY A 189
GLY A 160
GLY A 196
 None
 0.43A 3bogD-1pojA:
undetectable		 3bogD-1pojA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		3 / 3 GLY A  14
ASP A  27
SER A  40
 None
 0.65A 3brfA-1pojA:
undetectable		 3brfA-1pojA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 8 SER A 141
VAL A 139
THR A 198
VAL A 152
 None
 0.89A 3fhxB-1pojA:
2.3		 3fhxB-1pojA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 LEU A  89
LEU A  60
ILE A 128
SER A 129
ILE A 348
 None
 1.06A 3frqB-1pojA:
undetectable		 3frqB-1pojA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 LEU A 227
ASP A 252
LEU A 103
LEU A 133
PHE A 339
 None
None
KCX  A 162 ( 4.2A)
KCX  A 162 ( 4.2A)
None
 1.23A 3glqA-1pojA:
undetectable		 3glqA-1pojA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 8 LEU A  11
THR A  10
GLY A  33
ILE A 348
 None
 0.82A 3jusB-1pojA:
undetectable		 3jusB-1pojA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 ASP A 252
LEU A 103
LEU A 133
GLY A 160
PHE A 339
 None
KCX  A 162 ( 4.2A)
KCX  A 162 ( 4.2A)
None
None
 1.35A 3n58A-1pojA:
undetectable		 3n58A-1pojA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 8 VAL A 152
GLY A 189
ARG A 186
GLY A 160
 None
 0.64A 3n9jB-1pojA:
undetectable		 3n9jB-1pojA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 ASP A 252
THR A 254
ASP A  66
LEU A 103
GLY A 102
 None
None
None
KCX  A 162 ( 4.2A)
None
 1.25A 3ondA-1pojA:
undetectable		 3ondA-1pojA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 ASP A 252
THR A 254
ASP A  66
LEU A 103
GLY A 102
 None
None
None
KCX  A 162 ( 4.2A)
None
 1.27A 3ondB-1pojA:
undetectable		 3ondB-1pojA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A  70
SER A 256
SER A 255
PHE A 307
 KCX  A 162 ( 4.2A)
ZN  A 601 ( 3.6A)
None
None
None
 1.27A 3ugrA-1pojA:
7.4		 3ugrA-1pojA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 8 ASP A 167
SER A 205
ARG A 233
GLY A 297
 None
None
AE1  A 401 (-2.8A)
None
 1.02A 4af0A-1pojA:
6.1		 4af0A-1pojA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 GLY A 105
HIS A  68
ASP A 285
HIS A 230
GLY A 288
 AE1  A 401 (-3.1A)
ZN  A 601 (-3.6A)
AE1  A 401 ( 2.6A)
ZN  A 602 ( 3.5A)
AE1  A 401 ( 4.1A)
 1.26A 4bz6C-1pojA:
undetectable		 4bz6C-1pojA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		6 / 12 HIS A  68
GLY A 102
ASP A 285
HIS A  70
PRO A  85
GLY A 286
 ZN  A 601 (-3.6A)
None
AE1  A 401 ( 2.6A)
ZN  A 601 ( 3.6A)
None
None
 1.46A 4bz6C-1pojA:
undetectable		 4bz6C-1pojA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 8 THR A  82
GLY A  75
ARG A 169
ILE A 302
PRO A 291
 None
AE1  A 401 (-3.5A)
AE1  A 401 (-3.3A)
None
AE1  A 401 (-4.4A)
 1.42A 4e1vA-1pojA:
undetectable		 4e1vA-1pojA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 8 THR A  82
GLY A  75
ARG A 169
ILE A 302
PRO A 291
 None
AE1  A 401 (-3.5A)
AE1  A 401 (-3.3A)
None
AE1  A 401 (-4.4A)
 1.46A 4e1vC-1pojA:
undetectable		 4e1vC-1pojA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 8 THR A  82
GLY A  75
ARG A 169
ILE A 302
PRO A 291
 None
AE1  A 401 (-3.5A)
AE1  A 401 (-3.3A)
None
AE1  A 401 (-4.4A)
 1.46A 4e1vD-1pojA:
undetectable		 4e1vD-1pojA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 8 THR A  82
GLY A  75
ARG A 169
ILE A 302
PRO A 291
 None
AE1  A 401 (-3.5A)
AE1  A 401 (-3.3A)
None
AE1  A 401 (-4.4A)
 1.47A 4e1vE-1pojA:
undetectable		 4e1vE-1pojA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 8 THR A  82
GLY A  75
ARG A 169
ILE A 302
PRO A 291
 None
AE1  A 401 (-3.5A)
AE1  A 401 (-3.3A)
None
AE1  A 401 (-4.4A)
 1.48A 4e1vH-1pojA:
undetectable		 4e1vH-1pojA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 5 HIS A  68
HIS A 201
HIS A 230
ASP A 285
 ZN  A 601 (-3.6A)
ZN  A 602 ( 2.8A)
ZN  A 602 ( 3.5A)
AE1  A 401 ( 2.6A)
 0.93A 4h9mA-1pojA:
22.6		 4h9mA-1pojA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 LEU A 103
VAL A 199
VAL A  69
PHE A 339
LEU A 332
 KCX  A 162 ( 4.2A)
KCX  A 162 ( 4.7A)
None
None
None
 1.27A 4ib4A-1pojA:
undetectable		 4ib4A-1pojA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 8 SER A 185
THR A 134
SER A 141
GLU A 114
 None
 1.25A 4qb9D-1pojA:
undetectable		 4qb9D-1pojA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 7 THR A 309
GLU A 308
GLY A 286
GLY A 306
 None
 0.89A 4rdxA-1pojA:
undetectable		 4rdxA-1pojA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 4 ALA A 153
VAL A 148
GLY A 146
THR A 145
 None
 0.96A 4ubeA-1pojA:
undetectable		 4ubeA-1pojA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 6 HIS A  68
HIS A  70
HIS A 201
HIS A 230
ASP A 285
 ZN  A 601 (-3.6A)
ZN  A 601 ( 3.6A)
ZN  A 602 ( 2.8A)
ZN  A 602 ( 3.5A)
AE1  A 401 ( 2.6A)
 0.78A 4ubpC-1pojA:
21.1		 4ubpC-1pojA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 7 VAL A 152
ILE A 155
LEU A  71
LEU A 116
 None
 0.98A 4xo7A-1pojA:
8.1		 4xo7A-1pojA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 8 VAL A  87
PHE A 307
GLY A 306
ALA A 305
GLY A 288
 None
None
None
None
AE1  A 401 ( 4.1A)
 1.32A 4zjzB-1pojA:
undetectable		 4zjzB-1pojA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 12 LEU A 227
ASP A 252
THR A 254
LEU A 103
GLY A 102
 None
None
None
KCX  A 162 ( 4.2A)
None
 1.42A 5m66A-1pojA:
undetectable		 5m66A-1pojA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 8 ARG A 186
VAL A 221
GLY A 188
LEU A 190
 None
 1.09A 5sxqB-1pojA:
0.0		 5sxqB-1pojA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 8 ARG A 186
VAL A 221
GLY A 188
LEU A 190
 None
 1.06A 5syjA-1pojA:
0.0		 5syjA-1pojA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		4 / 7 ARG A 371
ALA A 130
ILE A  65
LEU A 342
 None
 0.78A 5te8A-1pojA:
undetectable		 5te8A-1pojA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		5 / 6 PRO A 276
GLY A 274
LEU A 242
ARG A 279
VAL A 280
 None
 1.35A 5x80A-1pojA:
0.0
5x80B-1pojA:
0.0		 5x80A-1pojA:
20.26
5x80B-1pojA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		3 / 3 GLU A 239
LEU A 242
ARG A 246
 None
 0.56A 6d8fA-1pojA:
0.0		 6d8fA-1pojA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		3 / 3 GLY A 372
ASP A 355
ILE A 348
 None
 0.57A 6dgxB-1pojA:
undetectable		 6dgxB-1pojA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1poj ISOASPARTYL
DIPEPTIDASE
(Escherichia
coli) 		3 / 3 LEU A 116
GLY A  73
PHE A 307
 None
 0.59A 6exiC-1pojA:
undetectable		 6exiC-1pojA:
13.17