SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 1pov POLIOVIRUS NATIVE
EMPTY CAPSID (TYPE
1)
(Enterovirus
C) 		4 / 7 LEU 0 320
ILE 0  73
THR 0 276
MET 0 325
 None
 1.30A 1kglA-1pov0:
0.0		 1kglA-1pov0:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1pov POLIOVIRUS NATIVE
EMPTY CAPSID (TYPE
1)
(Enterovirus
C) 		5 / 12 LEU 0 301
PHE 0 226
LEU 0 277
VAL 0 177
VAL 0 196
 None
 1.17A 2po5A-1pov0:
undetectable		 2po5A-1pov0:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1pov POLIOVIRUS NATIVE
EMPTY CAPSID (TYPE
1)
(Enterovirus
C) 		5 / 11 LEU 0 301
PHE 0 226
LEU 0 277
VAL 0 177
VAL 0 196
 None
 1.16A 2po5B-1pov0:
undetectable		 2po5B-1pov0:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_B_P77B204_1
(PROTEIN S100-A4)		 1pov POLIOVIRUS NATIVE
EMPTY CAPSID (TYPE
1)
(Enterovirus
C) 		4 / 6 MET 0 199
CYH 0 200
PHE 0 243
PHE 0 226
 None
 1.28A 3m0wB-1pov0:
undetectable
3m0wJ-1pov0:
undetectable		 3m0wB-1pov0:
13.27
3m0wJ-1pov0:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 1pov POLIOVIRUS NATIVE
EMPTY CAPSID (TYPE
1)
(Enterovirus
C) 		5 / 11 PHE 0 226
GLY 0 228
LEU 0 301
GLY 0 146
ALA 0 103
 None
 1.14A 4l6v1-1pov0:
undetectable
4l6v6-1pov0:
undetectable		 4l6v1-1pov0:
18.25
4l6v6-1pov0:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1pov POLIOVIRUS NATIVE
EMPTY CAPSID (TYPE
1)
(Enterovirus
C) 		4 / 6 VAL 0 179
ALA 0 275
GLN 0 265
VAL 0 193
 None
 1.06A 5i8fA-1pov0:
0.0		 5i8fA-1pov0:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 1pov POLIOVIRUS NATIVE
EMPTY CAPSID (TYPE
1)
(Enterovirus
C) 		5 / 10 VAL 0 177
ILE 0 322
LEU 0 155
GLY 0 297
ALA 0 195
 None
 0.99A 5mxbA-1pov0:
undetectable		 5mxbA-1pov0:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 1pov POLIOVIRUS NATIVE
EMPTY CAPSID (TYPE
1)
(Enterovirus
C) 		5 / 10 VAL 0 193
GLY 0 192
ALA 0 275
ASN 0 268
ASN 0 272
 None
 1.22A 5x6yB-1pov0:
undetectable		 5x6yB-1pov0:
16.97