SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pox'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		4 / 8 GLY A  31
TYR A  53
HIS A 464
VAL A 458
 None
 0.91A 1dbbH-1poxA:
undetectable
1dbbL-1poxA:
undetectable		 1dbbH-1poxA:
15.04
1dbbL-1poxA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 10 PHE A 472
VAL A 376
VAL A 470
ASN A 381
ILE A 414
 None
 1.17A 1fe2A-1poxA:
0.0		 1fe2A-1poxA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 8 ALA A  67
ASP A  96
ILE A 414
GLY A 428
ILE A 430
 None
 1.26A 1sh9A-1poxA:
undetectable		 1sh9A-1poxA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 10 ARG A 515
ILE A 397
ILE A 392
GLY A 425
ILE A 426
 None
 1.06A 1sh9B-1poxA:
undetectable		 1sh9B-1poxA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		3 / 3 ALA A 351
VAL A 353
TRP A 356
 None
 0.87A 1tkqB-1poxA:
undetectable		 1tkqB-1poxA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		4 / 5 ILE A 383
ILE A 397
ILE A 540
LEU A 407
 None
 0.79A 1zgyA-1poxA:
0.1		 1zgyA-1poxA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 LEU A 107
VAL A  78
ILE A  51
ILE A  18
ALA A  43
 None
 1.09A 2gj5A-1poxA:
undetectable		 2gj5A-1poxA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		4 / 7 GLY A  87
GLY A  86
VAL A 165
LEU A  94
 None
 0.68A 2oa1B-1poxA:
2.3		 2oa1B-1poxA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		4 / 6 ILE A  51
PRO A 173
LEU A 107
ILE A  40
 None
 0.95A 2q83B-1poxA:
0.0		 2q83B-1poxA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 8 GLY A  62
ALA A  63
ASP A  96
GLY A  77
VAL A 165
 None
 1.16A 3em6A-1poxA:
undetectable		 3em6A-1poxA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 448
ASN A 469
VAL A 467
GLY A 425
ILE A 426
 TPP  A 611 (-3.4A)
None
None
None
None
 1.23A 3k13B-1poxA:
undetectable		 3k13B-1poxA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		6 / 12 ALA A  67
ASP A  96
ASP A 100
ILE A 414
GLY A 428
ILE A 430
 None
 1.21A 3so9B-1poxA:
undetectable		 3so9B-1poxA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 GLN A 122
GLY A  81
GLY A 109
ALA A  83
GLY A  86
 None
 1.16A 3tegA-1poxA:
undetectable		 3tegA-1poxA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 7 PRO A 427
GLY A  62
ALA A  65
ALA A  97
ASP A  96
 None
 1.47A 3ur0B-1poxA:
0.0		 3ur0B-1poxA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		3 / 3 PRO A 427
ASP A 456
GLU A  60
 None
 0.87A 3v4tC-1poxA:
0.0		 3v4tC-1poxA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		3 / 3 PHE A 302
TYR A 287
TYR A 218
 None
FAD  A 612 (-4.7A)
None
 1.08A 4ffwA-1poxA:
2.8		 4ffwA-1poxA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 SER A 451
MET A 454
LEU A 539
PHE A 502
THR A 473
 None
 1.37A 4iarA-1poxA:
undetectable		 4iarA-1poxA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 VAL A  17
GLY A 109
GLY A  81
ILE A  40
LEU A 146
 None
 0.99A 4iv0A-1poxA:
undetectable		 4iv0A-1poxA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 222
GLY A 220
ASP A 308
ILE A 307
HIS A 101
 FAD  A 612 (-3.3A)
FAD  A 612 (-3.0A)
None
FAD  A 612 (-3.8A)
FAD  A 612 (-3.9A)
 0.99A 4iv0B-1poxA:
3.8		 4iv0B-1poxA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 VAL A  78
ILE A  18
VAL A  17
LEU A 146
LEU A  21
 None
 1.04A 4m11B-1poxA:
0.0		 4m11B-1poxA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		6 / 12 ILE A  37
ALA A  83
GLN A 167
LEU A 146
VAL A 149
ILE A  40
 None
 1.47A 4m2xG-1poxA:
undetectable		 4m2xG-1poxA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 ALA A  97
GLY A  77
LEU A  29
ILE A  54
GLY A  62
 None
 1.00A 4n48B-1poxA:
undetectable		 4n48B-1poxA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		6 / 10 LEU A 237
LEU A 230
LEU A 330
ILE A 333
LEU A 334
LEU A 210
 None
 1.35A 4odoA-1poxA:
undetectable		 4odoA-1poxA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		6 / 10 LEU A 237
LEU A 230
LEU A 330
ILE A 333
LEU A 334
LEU A 210
 None
 1.37A 4odoB-1poxA:
undetectable		 4odoB-1poxA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		6 / 10 LEU A 237
LEU A 230
LEU A 330
ILE A 333
LEU A 334
LEU A 210
 None
 1.38A 4odoC-1poxA:
undetectable		 4odoC-1poxA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		6 / 11 PRO A 215
LEU A 237
LEU A 230
LEU A 330
ILE A 333
LEU A 334
 None
 1.22A 4odrA-1poxA:
undetectable
4odrB-1poxA:
undetectable		 4odrA-1poxA:
10.63
4odrB-1poxA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		3 / 3 GLY A 369
PRO A 370
GLN A 375
 None
 0.31A 4oltB-1poxA:
0.0		 4oltB-1poxA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		3 / 3 ASP A 151
TYR A 183
TRP A  24
 None
 1.09A 4p7nA-1poxA:
undetectable		 4p7nA-1poxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		3 / 3 GLY A 369
PRO A 370
GLN A 375
 None
 0.24A 4qwpB-1poxA:
0.0		 4qwpB-1poxA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 THR A 206
VAL A 202
THR A 236
GLN A 232
ILE A 217
 None
 1.36A 4s0vA-1poxA:
2.5		 4s0vA-1poxA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		4 / 7 ILE A  37
GLU A 126
GLY A  87
GLY A  81
 None
 0.84A 5a06A-1poxA:
2.2		 5a06A-1poxA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		4 / 4 VAL A 149
ILE A 168
ASN A 127
VAL A 165
 None
 1.35A 5ajqA-1poxA:
undetectable		 5ajqA-1poxA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 TYR A 359
TRP A 356
LEU A 550
TYR A 374
ASN A 400
 None
 1.47A 5dsgB-1poxA:
undetectable		 5dsgB-1poxA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		4 / 7 ILE A 426
GLY A 425
PHE A 526
PHE A 514
 None
 1.06A 5hieA-1poxA:
0.0		 5hieA-1poxA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		3 / 3 LEU A 274
TYR A 287
SER A 293
 None
FAD  A 612 (-4.7A)
None
 0.83A 5iktA-1poxA:
undetectable		 5iktA-1poxA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		3 / 3 GLY A  34
GLY A  35
GLN A 122
 None
 0.33A 5imsA-1poxA:
37.2		 5imsA-1poxA:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 10 ALA A 184
ILE A  18
ILE A  51
VAL A  26
ALA A 186
 None
 1.22A 5nukA-1poxA:
0.0		 5nukA-1poxA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 10 LEU A  29
GLY A  31
GLY A  62
VAL A 104
LEU A 105
 None
 1.09A 5o96E-1poxA:
undetectable
5o96F-1poxA:
undetectable		 5o96E-1poxA:
17.93
5o96F-1poxA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 11 GLY A  62
ALA A  63
ALA A  65
ILE A 430
VAL A  56
 None
 1.10A 5yk2A-1poxA:
0.0		 5yk2A-1poxA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		4 / 6 GLY A 220
THR A 244
TYR A 258
TYR A 219
 FAD  A 612 (-3.0A)
FAD  A 612 (-3.1A)
None
None
 1.05A 6ag0C-1poxA:
undetectable		 6ag0C-1poxA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		6 / 12 GLY A 284
ASP A 306
ILE A 307
ASP A 308
ASP A 325
ALA A 326
 FAD  A 612 (-3.4A)
FAD  A 612 (-2.9A)
FAD  A 612 (-3.8A)
None
FAD  A 612 (-3.9A)
FAD  A 612 (-3.4A)
 0.63A 6bq4A-1poxA:
undetectable		 6bq4A-1poxA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_B_ADNB401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 222
ILE A 307
ASP A 308
ASP A 325
ALA A 326
 FAD  A 612 (-3.3A)
FAD  A 612 (-3.8A)
None
FAD  A 612 (-3.9A)
FAD  A 612 (-3.4A)
 1.09A 6bq4B-1poxA:
undetectable		 6bq4B-1poxA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_B_ADNB401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		6 / 12 GLY A 284
ASP A 306
ILE A 307
ASP A 308
ASP A 325
ALA A 326
 FAD  A 612 (-3.4A)
FAD  A 612 (-2.9A)
FAD  A 612 (-3.8A)
None
FAD  A 612 (-3.9A)
FAD  A 612 (-3.4A)
 0.66A 6bq4B-1poxA:
undetectable		 6bq4B-1poxA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		6 / 10 VAL A  17
ILE A  40
GLY A 109
ILE A 108
VAL A 149
ILE A 150
 None
 1.35A 6dj2A-1poxA:
undetectable		 6dj2A-1poxA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		5 / 11 ASP A 566
PHE A 570
ILE A 567
LEU A 557
PRO A 551
 None
 1.33A 6fgcA-1poxA:
0.0		 6fgcA-1poxA:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 1pox PYRUVATE OXIDASE
(Lactobacillus
plantarum) 		4 / 7 ARG A 224
ALA A 226
ILE A 221
ALA A 247
 None
None
FAD  A 612 (-3.8A)
FAD  A 612 ( 4.6A)
 0.91A 6ma7A-1poxA:
0.0		 6ma7A-1poxA:
8.17