SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pp0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		3 / 3 ASP A  64
ASP A  61
ASP A  88
 None
 0.75A 1eizA-1pp0A:
undetectable		 1eizA-1pp0A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		3 / 3 ASP A  64
ASP A  61
ASP A  88
 None
 0.77A 1ej0A-1pp0A:
undetectable		 1ej0A-1pp0A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		3 / 3 LEU A  13
PRO A  14
LEU A  17
 None
 0.44A 1hrkA-1pp0A:
undetectable		 1hrkA-1pp0A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 7 SER A 139
ASP A  11
SER A 152
VAL A 154
 None
 0.53A 2hdnE-1pp0A:
undetectable
2hdnF-1pp0A:
undetectable
2hdnH-1pp0A:
undetectable		 2hdnE-1pp0A:
13.16
2hdnF-1pp0A:
19.40
2hdnH-1pp0A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 7 SER A 152
VAL A 154
SER A 139
ASP A  11
 None
 0.51A 2hdnF-1pp0A:
undetectable
2hdnG-1pp0A:
undetectable
2hdnH-1pp0A:
undetectable		 2hdnF-1pp0A:
19.40
2hdnG-1pp0A:
13.16
2hdnH-1pp0A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 6 SER A 139
ASP A  11
SER A 152
VAL A 154
 None
 0.56A 2hdnI-1pp0A:
undetectable
2hdnJ-1pp0A:
undetectable
2hdnL-1pp0A:
undetectable		 2hdnI-1pp0A:
13.16
2hdnJ-1pp0A:
19.40
2hdnL-1pp0A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 6 SER A 152
VAL A 154
SER A 139
ASP A  11
 None
 0.58A 2hdnJ-1pp0A:
undetectable
2hdnK-1pp0A:
0.0
2hdnL-1pp0A:
undetectable		 2hdnJ-1pp0A:
19.40
2hdnK-1pp0A:
13.16
2hdnL-1pp0A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		5 / 12 PHE A 107
ILE A 103
LEU A  99
LEU A 119
PHE A 138
 None
None
None
None
ACY  A4011 (-4.6A)
 1.22A 2jn3A-1pp0A:
2.0		 2jn3A-1pp0A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		3 / 3 ASP A  64
ASP A  61
ASP A  88
 None
 0.73A 3douA-1pp0A:
undetectable		 3douA-1pp0A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 6 LEU A  86
PHE A  85
ILE A 184
PHE A 180
 None
 0.90A 3ko0B-1pp0A:
0.2		 3ko0B-1pp0A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 5 LEU A  25
SER A  21
LEU A 137
PRO A   9
 None
 1.13A 3onnA-1pp0A:
0.0		 3onnA-1pp0A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		3 / 3 LEU A  13
PRO A  14
LEU A  17
 None
 0.43A 3w1wB-1pp0A:
undetectable		 3w1wB-1pp0A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 4 LEU A 104
ILE A 103
GLY A  76
ILE A  82
 None
 0.74A 5dzk3-1pp0A:
undetectable
5dzkm-1pp0A:
undetectable		 5dzk3-1pp0A:
2.33
5dzkm-1pp0A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 5 ILE A 103
GLY A  76
ILE A  82
LEU A 104
 None
 0.79A 5dzkB-1pp0A:
undetectable
5dzkI-1pp0A:
undetectable
5dzkW-1pp0A:
undetectable		 5dzkB-1pp0A:
21.21
5dzkI-1pp0A:
19.63
5dzkW-1pp0A:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 5 ILE A 103
GLY A  76
ILE A  82
LEU A 104
 None
 0.74A 5dzki-1pp0A:
undetectable
5dzkj-1pp0A:
undetectable
5dzkx-1pp0A:
undetectable		 5dzki-1pp0A:
19.63
5dzkj-1pp0A:
19.63
5dzkx-1pp0A:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 5 ILE A 103
GLY A  76
ILE A  82
LEU A 104
 None
 0.72A 5dzkd-1pp0A:
undetectable
5dzkk-1pp0A:
undetectable
5dzky-1pp0A:
undetectable		 5dzkd-1pp0A:
21.21
5dzkk-1pp0A:
19.63
5dzky-1pp0A:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 4 ILE A 103
GLY A  76
ILE A  82
LEU A 104
 None
 0.82A 5dzkl-1pp0A:
undetectable
5dzkz-1pp0A:
undetectable		 5dzkl-1pp0A:
19.63
5dzkz-1pp0A:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		5 / 10 PRO A  14
ALA A 197
PHE A 195
VAL A 191
PRO A 141
 None
 1.39A 5m0oA-1pp0A:
undetectable		 5m0oA-1pp0A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 7 SER A  21
ILE A  22
LEU A  13
PRO A   9
 None
 1.02A 5u4sA-1pp0A:
undetectable		 5u4sA-1pp0A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pp0 VOLVATOXIN A2
(Volvariella
volvacea) 		4 / 6 GLN A   8
PHE A   7
LEU A 153
PHE A  90
 ACY  A4004 (-3.0A)
None
None
None
 1.30A 6nmpC-1pp0A:
undetectable
6nmpJ-1pp0A:
0.0		 6nmpC-1pp0A:
18.63
6nmpJ-1pp0A:
14.51