SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pp1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.07A 1ddsA-1pp1X:
undetectable
1ddsA-1pp1X:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.02A 1dyiA-1pp1X:
undetectable
1dyiA-1pp1X:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.03A 1dyiB-1pp1X:
undetectable
1dyiB-1pp1X:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 HIS X 139
LEU X 185
LEU X 143
SER X  75
None
0.98A 1i7zA-1pp1X:
undetectable
1i7zA-1pp1X:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 6 ASN X 198
ARG X 287
ILE X 149
GLY X 150
None
0.88A 1oniA-1pp1X:
undetectable
1oniB-1pp1X:
undetectable
1oniA-1pp1X:
16.98
1oniB-1pp1X:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 6 ASN X 198
ARG X 287
ILE X 149
GLY X 150
None
0.86A 1oniD-1pp1X:
undetectable
1oniF-1pp1X:
undetectable
1oniD-1pp1X:
16.98
1oniF-1pp1X:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 7 ILE X 149
GLY X 150
ASN X 198
ARG X 287
None
0.89A 1oniG-1pp1X:
undetectable
1oniI-1pp1X:
undetectable
1oniG-1pp1X:
16.98
1oniI-1pp1X:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 11 PHE X 282
LEU X 211
VAL X 207
MET X 223
LEU X 144
None
1.48A 1qabE-1pp1X:
0.0
1qabE-1pp1X:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.10A 1qzfA-1pp1X:
undetectable
1qzfA-1pp1X:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.10A 1qzfB-1pp1X:
undetectable
1qzfB-1pp1X:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.10A 1qzfC-1pp1X:
undetectable
1qzfC-1pp1X:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.10A 1qzfD-1pp1X:
undetectable
1qzfD-1pp1X:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.10A 1qzfE-1pp1X:
undetectable
1qzfE-1pp1X:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
0.98A 1rd7B-1pp1X:
undetectable
1rd7B-1pp1X:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.07A 1rg7A-1pp1X:
undetectable
1rg7A-1pp1X:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.07A 1tdrA-1pp1X:
undetectable
1tdrA-1pp1X:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ALA X 193
LEU X  82
ILE X 136
PHE X 206
PHE X  90
None
1.40A 1y0xX-1pp1X:
undetectable
1y0xX-1pp1X:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 ILE X 136
ARG X 126
LEU X 128
GLU X 132
None
0.91A 2cdqA-1pp1X:
undetectable
2cdqA-1pp1X:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 11 THR X 240
THR X 239
ARG X 346
ALA X 246
SER X 310
None
1.21A 2f162-1pp1X:
undetectable
2f162-1pp1X:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 11 THR X 240
THR X 239
ARG X 346
ALA X 246
SER X 310
None
1.19A 2f16N-1pp1X:
undetectable
2f16N-1pp1X:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 LEU X 211
GLY X 284
GLY X 150
ILE X 149
VAL X 207
None
0.92A 2nnkB-1pp1X:
undetectable
2nnkB-1pp1X:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 7 ILE X  83
PHE X 206
ILE X 197
PHE X  90
None
1.24A 2qb4A-1pp1X:
0.0
2qb4A-1pp1X:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 SER X 205
VAL X  95
GLY X  94
TRP X 202
None
1.02A 2qd3A-1pp1X:
undetectable
2qd3A-1pp1X:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 HIS X 276
ASP X 275
HIS X 288
ASP X 290
None
0.91A 2xadA-1pp1X:
undetectable
2xadA-1pp1X:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 HIS X 276
ASP X 275
HIS X 288
ASP X 290
None
0.89A 2xadB-1pp1X:
undetectable
2xadB-1pp1X:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 HIS X 276
ASP X 275
HIS X 288
ASP X 290
None
0.89A 2xadC-1pp1X:
undetectable
2xadC-1pp1X:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 HIS X 276
ASP X 275
HIS X 288
ASP X 290
None
0.93A 2xadD-1pp1X:
undetectable
2xadD-1pp1X:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 11 THR X 240
THR X 239
ARG X 346
ALA X 246
SER X 310
None
1.17A 3mg0N-1pp1X:
undetectable
3mg0N-1pp1X:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 6 ASN X 301
PHE X 299
ALA X 303
THR X 237
None
1.00A 3t3sB-1pp1X:
undetectable
3t3sB-1pp1X:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 8 ALA X 329
ASN X 301
PHE X 299
ALA X 303
THR X 237
None
1.04A 3t3sD-1pp1X:
undetectable
3t3sD-1pp1X:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 ALA X 329
ASN X 301
ALA X 303
THR X 237
None
0.97A 3t3sE-1pp1X:
undetectable
3t3sE-1pp1X:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 ALA X 329
ASN X 301
ALA X 303
THR X 237
None
0.95A 3t3sF-1pp1X:
0.0
3t3sF-1pp1X:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 5 HIS X  44
SER X  99
THR X  73
GLU X  98
None
1.40A 3tm4A-1pp1X:
undetectable
3tm4A-1pp1X:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 5 HIS X  44
SER X  99
THR X  73
GLU X  98
None
1.38A 3tm4B-1pp1X:
undetectable
3tm4B-1pp1X:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 11 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.01A 3tqbA-1pp1X:
undetectable
3tqbA-1pp1X:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.03A 4dfrA-1pp1X:
undetectable
4dfrA-1pp1X:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 7 ARG X  97
SER X 205
VAL X  95
TRP X 202
None
1.12A 4klaA-1pp1X:
0.0
4klaA-1pp1X:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 11 PRO X 190
LEU X  82
ILE X 226
LEU X 210
ILE X 155
None
1.03A 4odrA-1pp1X:
undetectable
4odrB-1pp1X:
undetectable
4odrA-1pp1X:
14.59
4odrB-1pp1X:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.01A 4qleA-1pp1X:
undetectable
4qleA-1pp1X:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
1.05A 4qlgB-1pp1X:
undetectable
4qlgB-1pp1X:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 5 ARG X  97
GLY X  48
ALA X 116
GLY X  46
None
0.94A 4u9uB-1pp1X:
undetectable
4u9uB-1pp1X:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 11 LEU X 144
LEU X 211
ALA X 233
VAL X 229
ILE X 149
None
1.15A 4x20D-1pp1X:
undetectable
4x20D-1pp1X:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 ASP X 250
LEU X 253
THR X 240
ILE X 241
LEU X 302
None
0.99A 4x5gA-1pp1X:
undetectable
4x5gA-1pp1X:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 7 VAL X 257
GLY X 328
ALA X 329
SER X 330
None
0.91A 5f1aB-1pp1X:
undetectable
5f1aB-1pp1X:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
4 / 8 ILE X 145
GLY X 146
ASN X 189
PHE X  78
None
0.94A 5hieD-1pp1X:
undetectable
5hieD-1pp1X:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 THR X 240
THR X 239
ARG X 346
ALA X 246
SER X 310
None
1.19A 5lf3b-1pp1X:
undetectable
5lf3b-1pp1X:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 12 THR X 240
THR X 239
ARG X 346
ALA X 246
SER X 310
None
1.18A 5lf3N-1pp1X:
undetectable
5lf3N-1pp1X:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
3 / 3 LEU X 245
ALA X 246
LEU X 266
None
0.46A 5uunB-1pp1X:
undetectable
5uunB-1pp1X:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)
1pp1 P40 NUCLEOPROTEIN
(Borna
disease
virus)
5 / 8 LEU X  76
ASN X 198
VAL X 147
LEU X 143
ILE X 194
None
1.38A 6cb4A-1pp1X:
undetectable
6cb4A-1pp1X:
21.54