SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ppr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		3 / 3 ALA M 238
VAL M 241
TRP M 186
 None
PID  M 624 (-4.2A)
PID  M 624 ( 3.6A)
 0.93A 1av2A-1pprM:
undetectable
1av2B-1pprM:
undetectable		 1av2A-1pprM:
7.10
1av2B-1pprM:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		3 / 3 TRP M 186
ALA M 238
VAL M 241
 PID  M 624 ( 3.6A)
None
PID  M 624 (-4.2A)
 0.94A 1av2C-1pprM:
undetectable
1av2D-1pprM:
undetectable		 1av2C-1pprM:
7.10
1av2D-1pprM:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		3 / 3 ALA M 238
VAL M 241
TRP M 186
 None
PID  M 624 (-4.2A)
PID  M 624 ( 3.6A)
 0.96A 1gmkA-1pprM:
undetectable
1gmkB-1pprM:
undetectable		 1gmkA-1pprM:
7.10
1gmkB-1pprM:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		3 / 3 ALA M 238
VAL M 241
TRP M 186
 None
PID  M 624 (-4.2A)
PID  M 624 ( 3.6A)
 0.95A 1gmkC-1pprM:
undetectable
1gmkD-1pprM:
undetectable		 1gmkC-1pprM:
7.10
1gmkD-1pprM:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		4 / 8 GLY M  71
ILE M  73
ILE M 207
ILE M 211
 None
PID  M 614 (-4.4A)
PID  M 612 (-4.1A)
CLA  M 601 (-4.1A)
 0.72A 1hshD-1pprM:
undetectable		 1hshD-1pprM:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		3 / 3 TRP M 186
ALA M 238
VAL M 241
 PID  M 624 ( 3.6A)
None
PID  M 624 (-4.2A)
 0.90A 1w5uA-1pprM:
undetectable
1w5uB-1pprM:
undetectable		 1w5uA-1pprM:
7.10
1w5uB-1pprM:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		4 / 5 LEU M  58
ALA M  91
LEU M  92
MET M  50
 None
None
PID  M 614 (-4.5A)
PID  M 613 ( 4.0A)
 1.25A 2oaxA-1pprM:
0.9		 2oaxA-1pprM:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		3 / 3 TRP M 186
ALA M 238
VAL M 241
 PID  M 624 ( 3.6A)
None
PID  M 624 (-4.2A)
 0.97A 3l8lC-1pprM:
undetectable
3l8lD-1pprM:
undetectable		 3l8lC-1pprM:
7.10
3l8lD-1pprM:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		4 / 4 ILE M  73
SER M  72
ASP M 208
ASP M 268
 PID  M 614 (-4.4A)
None
None
None
 1.24A 4krhB-1pprM:
undetectable		 4krhB-1pprM:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		4 / 4 ALA M 221
ALA M 224
ALA M 225
ALA M 228
 None
None
CLA  M 602 (-3.5A)
None
 0.09A 4oadA-1pprM:
0.0		 4oadA-1pprM:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		4 / 4 ALA M 221
ALA M 224
ALA M 225
ALA M 228
 None
None
CLA  M 602 (-3.5A)
None
 0.11A 4oaeA-1pprM:
0.0		 4oaeA-1pprM:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		5 / 12 SER M 174
GLY M 255
ASP M 218
ILE M 166
ASP M 164
 None
 1.36A 4pghB-1pprM:
undetectable		 4pghB-1pprM:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		5 / 8 ALA M   6
VAL M 145
GLY M   4
ALA M  90
GLY M  93
 None
 1.21A 4zjzB-1pprM:
undetectable		 4zjzB-1pprM:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		5 / 8 ALA M 169
VAL M 307
GLY M 167
ALA M 252
GLY M 255
 None
 1.17A 4zjzB-1pprM:
undetectable		 4zjzB-1pprM:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		3 / 3 TYR M 247
ALA M 253
LEU M 254
 None
None
PID  M 624 (-4.4A)
 0.63A 6ag0C-1pprM:
undetectable		 6ag0C-1pprM:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 1ppr PERIDININ-CHLOROPHYL
L PROTEIN
(Amphidinium
carterae) 		4 / 7 ASP M  86
ASN M  89
ALA M  90
LEU M  10
 None
PID  M 614 (-4.0A)
None
CLA  M 601 ( 4.9A)
 0.96A 6ci6A-1pprM:
1.7		 6ci6A-1pprM:
11.39