SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pq5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		8 / 8 HIS A  56
ASP A 189
SER A 190
GLN A 192
SER A 195
VAL A 210
GLY A 213
GLY A 223
 ARG  A 703 (-4.3A)
ARG  A 703 (-2.0A)
ARG  A 703 (-2.5A)
ARG  A 703 (-3.1A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.50A 1aq7A-1pq5A:
34.1		 1aq7A-1pq5A:
44.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 9 ASP A 189
SER A 195
VAL A 210
TRP A 212
GLY A 213
GLY A 223
 ARG  A 703 (-2.0A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
None
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.40A 1bcuH-1pq5A:
33.3		 1bcuH-1pq5A:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DWC_H_MITH1_1
(ALPHA-THROMBIN
(LARGE SUBUNIT))		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 9 HIS A  56
ASP A 189
SER A 195
TRP A 212
GLY A 223
 ARG  A 703 (-4.3A)
ARG  A 703 (-2.0A)
ARG  A 703 (-2.3A)
None
ARG  A 703 (-2.6A)
 0.40A 1dwcH-1pq5A:
32.4		 1dwcH-1pq5A:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		7 / 12 HIS A  56
ASP A 189
SER A 195
VAL A 210
TRP A 212
GLY A 213
GLY A 223
 ARG  A 703 (-4.3A)
ARG  A 703 (-2.0A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
None
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.54A 1etrH-1pq5A:
32.5		 1etrH-1pq5A:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 8 ASP A 189
SER A 190
SER A 195
VAL A 210
GLY A 213
GLY A 223
 ARG  A 703 (-2.0A)
ARG  A 703 (-2.5A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.38A 1f5lA-1pq5A:
34.0		 1f5lA-1pq5A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 6 ASP A 189
SER A 190
SER A 195
VAL A 210
GLY A 213
GLY A 223
 ARG  A 703 (-2.0A)
ARG  A 703 (-2.5A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.28A 1tnlA-1pq5A:
34.0		 1tnlA-1pq5A:
44.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 10 ALA A  54
THR A  53
ALA A 101
ALA A  55
GLY A 208
ALA A 226
 None
 1.29A 2f16K-1pq5A:
undetectable
2f16L-1pq5A:
undetectable		 2f16K-1pq5A:
22.40
2f16L-1pq5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 10 ALA A  54
THR A  53
ALA A 101
ALA A  55
GLY A 208
ALA A 226
 None
 1.29A 2f16Y-1pq5A:
undetectable
2f16Z-1pq5A:
undetectable		 2f16Y-1pq5A:
22.40
2f16Z-1pq5A:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 6 ASP A 189
SER A 190
SER A 195
VAL A 210
GLY A 213
GLY A 223
 ARG  A 703 (-2.0A)
ARG  A 703 (-2.5A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.25A 2otvA-1pq5A:
34.0		 2otvA-1pq5A:
44.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 12 GLY A 139
GLY A  43
GLY A 196
GLY A 193
THR A  53
LEU A  52
 None
None
None
ARG  A 703 (-3.6A)
None
None
 1.44A 2oxtD-1pq5A:
undetectable		 2oxtD-1pq5A:
21.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		7 / 12 ASP A 189
SER A 195
VAL A 210
TRP A 212
GLY A 213
GLY A 223
TYR A 225
 ARG  A 703 (-2.0A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
None
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
None
 0.31A 2p16A-1pq5A:
32.8		 2p16A-1pq5A:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 8 ASP A 189
SER A 190
SER A 195
VAL A 210
GLY A 213
GLY A 223
 ARG  A 703 (-2.0A)
ARG  A 703 (-2.5A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.30A 2vinA-1pq5A:
13.7		 2vinA-1pq5A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		8 / 12 ASP A 189
SER A 195
VAL A 210
TRP A 212
GLY A 213
GLY A 215
GLY A 223
TYR A 225
 ARG  A 703 (-2.0A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
None
ARG  A 703 ( 3.7A)
ARG  A 703 (-4.3A)
ARG  A 703 (-2.6A)
None
 0.38A 2w26A-1pq5A:
15.3		 2w26A-1pq5A:
34.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 11 ALA A 209
TYR A  93
ALA A  54
GLY A 196
SER A 195
 None
None
None
None
ARG  A 703 (-2.3A)
 1.02A 2xfsB-1pq5A:
undetectable		 2xfsB-1pq5A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 11 SER A  86
SER A  85
LEU A  45
SER A 106
LEU A 105
 None
 0.87A 2xn5A-1pq5A:
undetectable		 2xn5A-1pq5A:
19.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		8 / 11 HIS A  56
ASP A 189
SER A 190
GLN A 192
SER A 195
TRP A 212
GLY A 213
GLY A 223
 ARG  A 703 (-4.3A)
ARG  A 703 (-2.0A)
ARG  A 703 (-2.5A)
ARG  A 703 (-3.1A)
ARG  A 703 (-2.3A)
None
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.36A 3gy3A-1pq5A:
34.3		 3gy3A-1pq5A:
44.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		4 / 4 GLY A 213
VAL A 224
GLY A 170
THR A 171
 ARG  A 703 ( 3.7A)
None
None
None
 0.81A 3ib2A-1pq5A:
undetectable		 3ib2A-1pq5A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 12 GLY A 229
ASP A 126
PRO A 127
LEU A 100
ILE A 235
 None
 0.95A 3ku1C-1pq5A:
undetectable		 3ku1C-1pq5A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 12 ALA A  54
THR A  53
ALA A 101
ALA A  55
GLY A 208
ALA A 226
 None
 1.29A 3mg0Y-1pq5A:
undetectable
3mg0Z-1pq5A:
0.0		 3mg0Y-1pq5A:
22.40
3mg0Z-1pq5A:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 6 SER A 190
SER A 195
VAL A 210
TRP A 212
GLY A 213
GLY A 223
 ARG  A 703 (-2.5A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
None
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.38A 3rxfA-1pq5A:
17.6		 3rxfA-1pq5A:
44.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 5 ASP A 189
SER A 190
SER A 195
VAL A 210
GLY A 223
 ARG  A 703 (-2.0A)
ARG  A 703 (-2.5A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
ARG  A 703 (-2.6A)
 0.37A 3rxhA-1pq5A:
34.2		 3rxhA-1pq5A:
44.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		4 / 5 HIS A  56
GLN A 192
GLY A 193
SER A 195
 ARG  A 703 (-4.3A)
ARG  A 703 (-3.1A)
ARG  A 703 (-3.6A)
ARG  A 703 (-2.3A)
 0.89A 4fu8A-1pq5A:
34.2		 4fu8A-1pq5A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HFP_D_15UD402_1
(PROTHROMBIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 12 HIS A  56
ASP A 189
VAL A 210
TRP A 212
GLY A 223
 ARG  A 703 (-4.3A)
ARG  A 703 (-2.0A)
ARG  A 703 (-4.5A)
None
ARG  A 703 (-2.6A)
 0.33A 4hfpD-1pq5A:
32.2		 4hfpD-1pq5A:
34.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		4 / 8 LYS A 154
THR A 134
ALA A 136
VAL A 200
 None
 0.73A 4iizB-1pq5A:
undetectable		 4iizB-1pq5A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		4 / 8 LYS A 154
THR A 134
ALA A 136
VAL A 200
 None
 0.77A 4ik6B-1pq5A:
undetectable		 4ik6B-1pq5A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		4 / 8 ALA A 133
GLY A 182
VAL A 210
ILE A 199
 None
None
ARG  A 703 (-4.5A)
None
 0.74A 4ll3A-1pq5A:
undetectable		 4ll3A-1pq5A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		3 / 3 VAL A 160
SER A 161
THR A 164
 None
 0.23A 4luhA-1pq5A:
undetectable		 4luhA-1pq5A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 10 PRO A 198
VAL A 210
ALA A 209
GLY A 139
GLY A  42
 None
ARG  A 703 (-4.5A)
None
None
None
 1.19A 4mmdA-1pq5A:
undetectable		 4mmdA-1pq5A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 12 PRO A 198
VAL A 210
ALA A 209
TYR A 225
GLY A 139
GLY A  42
 None
ARG  A 703 (-4.5A)
None
None
None
None
 1.48A 4mmdB-1pq5A:
undetectable		 4mmdB-1pq5A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 9 ALA A  54
THR A  53
ALA A  55
GLY A 208
ALA A 226
 None
 1.19A 4qvnK-1pq5A:
undetectable
4qvnL-1pq5A:
undetectable		 4qvnK-1pq5A:
22.62
4qvnL-1pq5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 9 ALA A  54
THR A  53
ALA A  55
GLY A 208
ALA A 226
 None
 1.19A 4qvnY-1pq5A:
undetectable
4qvnZ-1pq5A:
undetectable		 4qvnY-1pq5A:
22.62
4qvnZ-1pq5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 9 ALA A  54
THR A  53
ALA A  55
GLY A 208
ALA A 226
 None
 1.19A 4qvqK-1pq5A:
undetectable
4qvqL-1pq5A:
undetectable		 4qvqK-1pq5A:
22.40
4qvqL-1pq5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 9 ALA A  54
THR A  53
ALA A  55
GLY A 208
ALA A 226
 None
 1.18A 4qvqY-1pq5A:
undetectable
4qvqZ-1pq5A:
undetectable		 4qvqY-1pq5A:
22.40
4qvqZ-1pq5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 9 ILE A  30
VAL A  31
GLY A 197
ALA A 209
ILE A 235
VAL A  51
 None
 1.31A 4r21B-1pq5A:
undetectable		 4r21B-1pq5A:
17.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 12 HIS A  56
VAL A 210
TRP A 212
GLY A 213
GLY A 223
 ARG  A 703 (-4.3A)
ARG  A 703 (-4.5A)
None
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.37A 4rn6B-1pq5A:
26.8		 4rn6B-1pq5A:
34.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 8 LEU A  46
ALA A 118
LEU A 120
ALA A 209
LEU A 100
 None
 1.12A 4z90A-1pq5A:
undetectable
4z90B-1pq5A:
undetectable
4z90C-1pq5A:
undetectable
4z90D-1pq5A:
undetectable
4z90E-1pq5A:
undetectable		 4z90A-1pq5A:
22.12
4z90B-1pq5A:
22.12
4z90C-1pq5A:
22.12
4z90D-1pq5A:
22.12
4z90E-1pq5A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		5 / 8 LEU A 100
LEU A  46
ALA A 118
LEU A 120
ALA A 209
 None
 1.08A 4z90A-1pq5A:
undetectable
4z90B-1pq5A:
undetectable
4z90C-1pq5A:
undetectable
4z90D-1pq5A:
undetectable
4z90E-1pq5A:
undetectable		 4z90A-1pq5A:
22.12
4z90B-1pq5A:
22.12
4z90C-1pq5A:
22.12
4z90D-1pq5A:
22.12
4z90E-1pq5A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 12 GLY A 139
GLY A  43
GLY A 196
GLY A 193
THR A  53
VAL A  51
 None
None
None
ARG  A 703 (-3.6A)
None
None
 1.31A 5eiwC-1pq5A:
undetectable		 5eiwC-1pq5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 11 ALA A  54
THR A  53
ALA A 101
ALA A  55
GLY A 208
ALA A 226
 None
 1.29A 6hwdK-1pq5A:
undetectable
6hwdL-1pq5A:
undetectable		 6hwdK-1pq5A:
16.51
6hwdL-1pq5A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 11 ALA A  54
THR A  53
ALA A 101
ALA A  55
GLY A 208
ALA A 226
 None
 1.41A 6hwdK-1pq5A:
undetectable
6hwdL-1pq5A:
undetectable		 6hwdK-1pq5A:
16.51
6hwdL-1pq5A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 11 ALA A  54
THR A  53
ALA A 101
ALA A  55
GLY A 208
ALA A 226
 None
 1.29A 6hwdY-1pq5A:
undetectable
6hwdZ-1pq5A:
undetectable		 6hwdY-1pq5A:
16.51
6hwdZ-1pq5A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1pq5 TRYPSIN
(Fusarium
oxysporum) 		6 / 11 ALA A  54
THR A  53
ALA A 101
ALA A  55
GLY A 208
ALA A 226
 None
 1.41A 6hwdY-1pq5A:
undetectable
6hwdZ-1pq5A:
undetectable		 6hwdY-1pq5A:
16.51
6hwdZ-1pq5A:
14.73