SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pqs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1pqs CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 798
ILE A 795
PHE A 791
GLY A 829
 None
 0.72A 4ac9C-1pqsA:
undetectable		 4ac9C-1pqsA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1pqs CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 798
ILE A 795
PHE A 791
GLY A 829
 None
 0.75A 4acbC-1pqsA:
undetectable		 4acbC-1pqsA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1pqs CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 792
ASN A 799
SER A 830
 None
 0.71A 4obwA-1pqsA:
undetectable		 4obwA-1pqsA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1pqs CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 828
ASN A 799
LEU A 853
 None
 0.74A 6exiD-1pqsA:
undetectable		 6exiD-1pqsA:
19.10