SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I7Q_A_BEZA1501_0 (ANTHRANILATE SYNTHASE)	1pqz	MCMV M144 (Murid betaherpesvirus 1)	5 / 11	GLU A 36 GLY A 31 THR A 30 HIS A 32 GLY A 48	None	1.32A	1i7qA-1pqzA: 3.3	1i7qA-1pqzA: 19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I7Q_C_BEZC1502_0 (ANTHRANILATE SYNTHASE)	1pqz	MCMV M144 (Murid betaherpesvirus 1)	5 / 10	GLU A 36 GLY A 31 THR A 30 HIS A 32 GLY A 48	None	1.35A	1i7qC-1pqzA: 2.1	1i7qC-1pqzA: 19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FN1_A_SALA506_1 (SALICYLATE SYNTHETASE, IRP9)	1pqz	MCMV M144 (Murid betaherpesvirus 1)	5 / 11	GLU A 36 GLY A 31 THR A 30 HIS A 32 GLY A 48	None	1.42A	2fn1A-1pqzA: undetectable	2fn1A-1pqzA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FN1_B_SALB503_1 (SALICYLATE SYNTHETASE, IRP9)	1pqz	MCMV M144 (Murid betaherpesvirus 1)	5 / 11	GLU A 36 GLY A 31 THR A 30 HIS A 32 GLY A 48	None	1.42A	2fn1B-1pqzA: undetectable	2fn1B-1pqzA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	1pqz	MCMV M144 (Murid betaherpesvirus 1)	4 / 8	LEU A 235 PRO A 145 SER A 144 VAL A 149	None	1.01A	4klrB-1pqzA: undetectable	4klrB-1pqzA: 20.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1I7Q_A_BEZA1501_0","ANTHRANILATE SYNTHASE","1pqz","MCMV M144","Murid betaherpesvirus 1",5,"GLU A  36;GLY A  31;THR A  30;HIS A  32;GLY A  48","None","1.32A","1i7qA-1pqzA:3.3","1i7qA-1pqzA:19.58"],["1I7Q_C_BEZC1502_0","ANTHRANILATE SYNTHASE","1pqz","MCMV M144","Murid betaherpesvirus 1",5,"GLU A  36;GLY A  31;THR A  30;HIS A  32;GLY A  48","None","1.35A","1i7qC-1pqzA:2.1","1i7qC-1pqzA:19.58"],["2FN1_A_SALA506_1","SALICYLATE SYNTHETASE, IRP9","1pqz","MCMV M144","Murid betaherpesvirus 1",5,"GLU A  36;GLY A  31;THR A  30;HIS A  32;GLY A  48","None","1.42A","2fn1A-1pqzA:undetectable","2fn1A-1pqzA:21.26"],["2FN1_B_SALB503_1","SALICYLATE SYNTHETASE, IRP9","1pqz","MCMV M144","Murid betaherpesvirus 1",5,"GLU A  36;GLY A  31;THR A  30;HIS A  32;GLY A  48","None","1.42A","2fn1B-1pqzA:undetectable","2fn1B-1pqzA:21.26"],["4KLR_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","1pqz","MCMV M144","Murid betaherpesvirus 1",4,"LEU A 235;PRO A 145;SER A 144;VAL A 149","None","1.01A","4klrB-1pqzA:undetectable","4klrB-1pqzA:20.22"]]