SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1prn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1prn PORIN
(Rhodobacter
blasticus) 		3 / 3 THR A 183
GLU A 162
ASP A 156
 None
 0.72A 1nt2A-1prnA:
undetectable		 1nt2A-1prnA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1prn PORIN
(Rhodobacter
blasticus) 		4 / 8 PHE A 202
TYR A 230
ASN A 229
GLY A 206
 None
 1.07A 1ykiA-1prnA:
0.0
1ykiB-1prnA:
0.0		 1ykiA-1prnA:
23.13
1ykiB-1prnA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1prn PORIN
(Rhodobacter
blasticus) 		4 / 8 PHE A 202
TYR A 230
ASN A 229
GLY A 206
 None
 1.06A 1ykiC-1prnA:
0.0
1ykiD-1prnA:
0.0		 1ykiC-1prnA:
23.13
1ykiD-1prnA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 1prn PORIN
(Rhodobacter
blasticus) 		3 / 3 ARG A  30
SER A 119
TYR A   7
 None
 0.94A 2q2hA-1prnA:
undetectable
2q2hB-1prnA:
undetectable		 2q2hA-1prnA:
16.67
2q2hB-1prnA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 1prn PORIN
(Rhodobacter
blasticus) 		4 / 8 PHE A 195
ALA A  93
ALA A 199
THR A 207
 None
 1.12A 3t3sE-1prnA:
undetectable		 3t3sE-1prnA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 1prn PORIN
(Rhodobacter
blasticus) 		4 / 6 GLY A 186
GLU A 163
ASP A  86
ASN A 118
 None
 1.06A 3vywC-1prnA:
undetectable		 3vywC-1prnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 1prn PORIN
(Rhodobacter
blasticus) 		5 / 9 TYR A 240
VAL A 280
ALA A 281
GLY A 108
PHE A 107
 None
None
C8E  A 901 (-3.6A)
None
None
 1.31A 4mmeB-1prnA:
undetectable		 4mmeB-1prnA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1prn PORIN
(Rhodobacter
blasticus) 		5 / 12 SER A 112
GLY A 165
ASP A  90
ALA A 134
VAL A  85
 None
 1.17A 4u95B-1prnA:
undetectable		 4u95B-1prnA:
14.75