SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1prt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1prt PERTUSSIS TOXIN
(SUBUNIT S1)
(Bordetella
pertussis) 		4 / 8 SER A  40
ILE A 187
GLY A 189
GLY A 199
 None
 0.61A 1me7A-1prtA:
undetectable		 1me7A-1prtA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1prt PERTUSSIS TOXIN
(SUBUNIT S1)
(Bordetella
pertussis) 		4 / 7 SER A  52
SER A  54
GLN A 127
GLU A 129
 None
 0.90A 2c8aA-1prtA:
undetectable		 2c8aA-1prtA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1prt PERTUSSIS TOXIN
(SUBUNIT S1)
(Bordetella
pertussis) 		3 / 3 ARG A 143
THR A 156
THR A  60
 None
 0.81A 3k2hB-1prtA:
undetectable		 3k2hB-1prtA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1prt PERTUSSIS TOXIN
(SUBUNIT S1)
(Bordetella
pertussis) 		4 / 9 ALA A 206
GLU A 207
LEU A  64
ILE A  85
 None
 0.87A 4xtaA-1prtA:
undetectable		 4xtaA-1prtA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 1prt PERTUSSIS TOXIN
(SUBUNIT S1)
(Bordetella
pertussis) 		5 / 11 ALA A 124
ALA A 120
LEU A  36
LEU A 131
HIS A  35
 None
 1.14A 5eb5A-1prtA:
undetectable		 5eb5A-1prtA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1prt PERTUSSIS TOXIN
(SUBUNIT S1)
(Bordetella
pertussis) 		5 / 12 VAL A  32
ALA A  25
GLY A  99
ALA A 100
SER A 103
 None
 1.11A 5kirB-1prtA:
undetectable		 5kirB-1prtA:
18.80