SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1prx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 1prx HORF6
(Homo
sapiens) 		4 / 8 THR A  44
PRO A  45
VAL A  46
ALA A 151
 CSO  A  47 ( 3.6A)
None
CSO  A  47 ( 3.1A)
CSO  A  47 ( 4.1A)
 0.84A 2v32A-1prxA:
27.2
2v32B-1prxA:
27.3		 2v32A-1prxA:
62.95
2v32B-1prxA:
62.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1prx HORF6
(Homo
sapiens) 		4 / 8 PRO A  40
THR A  44
PRO A  45
VAL A  46
 CSO  A  47 ( 4.8A)
CSO  A  47 ( 3.6A)
None
CSO  A  47 ( 3.1A)
 0.52A 2v32C-1prxA:
27.1
2v32D-1prxA:
27.3		 2v32C-1prxA:
62.95
2v32D-1prxA:
62.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_A_BEZA1222_0
(PEROXIREDOXIN 6.)		 1prx HORF6
(Homo
sapiens) 		5 / 9 PRO A  40
THR A  44
PRO A  45
VAL A  46
ALA A 151
 CSO  A  47 ( 4.8A)
CSO  A  47 ( 3.6A)
None
CSO  A  47 ( 3.1A)
CSO  A  47 ( 4.1A)
 0.99A 2v41A-1prxA:
27.2
2v41B-1prxA:
27.4		 2v41A-1prxA:
62.95
2v41B-1prxA:
62.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)		 1prx HORF6
(Homo
sapiens) 		5 / 9 PRO A  40
THR A  44
PRO A  45
VAL A  46
ALA A 151
 CSO  A  47 ( 4.8A)
CSO  A  47 ( 3.6A)
None
CSO  A  47 ( 3.1A)
CSO  A  47 ( 4.1A)
 1.00A 2v41A-1prxA:
27.2
2v41B-1prxA:
27.4		 2v41A-1prxA:
62.95
2v41B-1prxA:
62.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 1prx HORF6
(Homo
sapiens) 		4 / 8 PRO A  40
THR A  44
PRO A  45
VAL A  46
 CSO  A  47 ( 4.8A)
CSO  A  47 ( 3.6A)
None
CSO  A  47 ( 3.1A)
 0.47A 2v41C-1prxA:
26.8
2v41D-1prxA:
27.2		 2v41C-1prxA:
62.95
2v41D-1prxA:
62.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 1prx HORF6
(Homo
sapiens) 		4 / 8 PRO A  40
THR A  44
PRO A  45
VAL A  46
 CSO  A  47 ( 4.8A)
CSO  A  47 ( 3.6A)
None
CSO  A  47 ( 3.1A)
 0.44A 2v41C-1prxA:
26.8
2v41D-1prxA:
27.2		 2v41C-1prxA:
62.95
2v41D-1prxA:
62.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 1prx HORF6
(Homo
sapiens) 		4 / 8 PRO A  40
THR A  44
PRO A  45
VAL A  46
 CSO  A  47 ( 4.8A)
CSO  A  47 ( 3.6A)
None
CSO  A  47 ( 3.1A)
 0.43A 2v41G-1prxA:
27.1
2v41H-1prxA:
27.4		 2v41G-1prxA:
62.95
2v41H-1prxA:
62.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1prx HORF6
(Homo
sapiens) 		4 / 5 VAL A 136
PHE A  25
ILE A  69
PHE A  14
 None
 1.01A 3owxB-1prxA:
0.0		 3owxB-1prxA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 1prx HORF6
(Homo
sapiens) 		4 / 6 ALA A  11
ASP A 140
LEU A   5
SER A 146
 None
 1.03A 4ot2A-1prxA:
undetectable		 4ot2A-1prxA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1prx HORF6
(Homo
sapiens) 		4 / 8 LEU A 161
ALA A  58
HIS A  39
ARG A 132
 None
None
CSO  A  47 ( 3.9A)
CSO  A  47 ( 4.7A)
 0.84A 4qrcA-1prxA:
undetectable		 4qrcA-1prxA:
20.68