SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1psh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		4 / 7 GLY A  29
HIS A  47
ASP A  48
TYR A  51
 CA  A 120 (-4.4A)
None
CA  A 120 (-2.0A)
None
 0.65A 1th6A-1pshA:
18.2		 1th6A-1pshA:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		4 / 7 HIS A  47
ASP A  48
TYR A  51
PRO A  62
 None
CA  A 120 (-2.0A)
None
None
 0.29A 1th6A-1pshA:
18.2		 1th6A-1pshA:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		4 / 7 GLY A  29
HIS A  47
ASP A  48
TYR A  51
 CA  A 120 (-4.4A)
None
CA  A 120 (-2.0A)
None
 0.67A 2armA-1pshA:
18.2		 2armA-1pshA:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		4 / 7 HIS A  47
ASP A  48
TYR A  51
PRO A  62
 None
CA  A 120 (-2.0A)
None
None
 0.31A 2armA-1pshA:
18.2		 2armA-1pshA:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		6 / 11 ILE A   9
TYR A  24
GLY A  29
LEU A  40
PHE A 100
TYR A 105
 None
None
CA  A 120 (-4.4A)
None
None
None
 0.65A 2azyA-1pshA:
19.3		 2azyA-1pshA:
54.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		4 / 7 LEU A   2
TRP A  18
ALA A  22
PHE A  64
 None
 0.69A 2wq5A-1pshA:
23.7		 2wq5A-1pshA:
96.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		4 / 7 TRP A  18
ALA A  22
GLY A  29
PHE A  64
 None
None
CA  A 120 (-4.4A)
None
 0.78A 2wq5A-1pshA:
23.7		 2wq5A-1pshA:
96.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		4 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  62
 None
CA  A 120 (-2.0A)
None
None
 0.32A 3fo7A-1pshA:
18.2		 3fo7A-1pshA:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		4 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  62
 None
CA  A 120 (-2.0A)
None
None
 0.39A 3h1xA-1pshA:
18.4		 3h1xA-1pshA:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		5 / 9 PHE A   5
ILE A   9
PHE A  21
GLY A  29
HIS A  47
 None
None
None
CA  A 120 (-4.4A)
None
 0.61A 3oshA-1pshA:
23.1		 3oshA-1pshA:
92.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		5 / 9 PHE A   5
ILE A   9
PHE A  21
HIS A  47
TYR A  63
 None
 0.30A 3oshA-1pshA:
23.1		 3oshA-1pshA:
92.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1psh PHOSPHOLIPASE A2
(Naja
naja) 		4 / 7 TYR A   3
LEU A   2
TRP A  19
ASN A   7
 None
 1.33A 4f8yC-1pshA:
undetectable
4f8yD-1pshA:
undetectable		 4f8yC-1pshA:
17.80
4f8yD-1pshA:
17.80