SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1psq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 10 PRO A  51
THR A  55
CYH A  58
LEU A   5
ARG A 127
 None
 1.05A 1h4oA-1psqA:
19.3
1h4oB-1psqA:
19.5		 1h4oA-1psqA:
25.70
1h4oB-1psqA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		4 / 8 PRO A  51
THR A  55
CYH A  58
ARG A 127
 None
 0.49A 1h4oB-1psqA:
19.5		 1h4oB-1psqA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 9 PRO A  51
THR A  55
CYH A  58
LEU A   5
ARG A 127
 None
 1.11A 1h4oD-1psqA:
19.3		 1h4oD-1psqA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 9 PRO A  51
THR A  55
CYH A  58
LEU A   5
ARG A 127
 None
 1.08A 1h4oF-1psqA:
19.3		 1h4oF-1psqA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 8 PRO A  51
THR A  55
CYH A  58
LEU A   5
ARG A 127
 None
 1.05A 1h4oG-1psqA:
19.3		 1h4oG-1psqA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 9 PRO A  51
THR A  55
CYH A  58
LEU A   5
ARG A 127
 None
 1.10A 1h4oH-1psqA:
19.4		 1h4oH-1psqA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 9 PRO A  51
THR A  55
CYH A  58
LEU A   5
ARG A 127
 None
 1.10A 1hd2A-1psqA:
19.3		 1hd2A-1psqA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		3 / 3 ASP A  41
ASP A  39
LYS A  45
 None
 1.04A 1lqtB-1psqA:
2.3		 1lqtB-1psqA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		3 / 3 ASP A  41
ASP A  39
LYS A  45
 None
 1.05A 1lquB-1psqA:
undetectable		 1lquB-1psqA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		4 / 8 PRO A  51
THR A  55
CYH A  58
ARG A 127
 None
 0.49A 1oc3A-1psqA:
19.6		 1oc3A-1psqA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 9 PRO A  51
THR A  55
CYH A  58
LEU A   5
ARG A 127
 None
 1.08A 1oc3B-1psqA:
19.2		 1oc3B-1psqA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		4 / 8 VAL A   2
LEU A 117
TYR A 143
ASP A 145
 None
 1.06A 2ddwA-1psqA:
undetectable		 2ddwA-1psqA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 12 LEU A  72
ALA A  70
ILE A 157
ALA A 160
ASP A  73
 None
 0.97A 2ejtA-1psqA:
undetectable		 2ejtA-1psqA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		4 / 7 THR A  75
ALA A  22
TYR A 115
LEU A  37
 None
 1.14A 2hzqA-1psqA:
undetectable		 2hzqA-1psqA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		3 / 3 SER A  26
ASP A 114
ASP A 108
 None
 0.74A 2plwA-1psqA:
undetectable		 2plwA-1psqA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 10 PRO A  51
THR A  55
CYH A  58
LEU A   5
ARG A 127
 None
 1.12A 2vl2A-1psqA:
19.6
2vl2C-1psqA:
16.9		 2vl2A-1psqA:
25.56
2vl2C-1psqA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		3 / 3 SER A  52
THR A  79
PHE A 153
 None
 0.62A 2x91A-1psqA:
undetectable		 2x91A-1psqA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		5 / 12 LEU A  72
ALA A  70
ILE A 157
ALA A 160
ASP A  73
 None
 1.09A 3axtA-1psqA:
2.0		 3axtA-1psqA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		4 / 7 VAL A  80
LEU A  27
PHE A 130
LEU A 132
 None
 1.01A 3qeoB-1psqA:
undetectable		 3qeoB-1psqA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		4 / 8 LEU A 103
ASP A 105
ASP A 108
SER A 110
 None
 1.02A 3qj7A-1psqA:
undetectable
3qj7D-1psqA:
undetectable		 3qj7A-1psqA:
24.25
3qj7D-1psqA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		4 / 4 ALA A 155
ALA A 158
ALA A 159
ALA A 162
 None
 0.12A 4oadA-1psqA:
0.0		 4oadA-1psqA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1psq PROBABLE THIOL
PEROXIDASE
(Streptococcus
pneumoniae) 		4 / 8 ALA A 128
VAL A 129
PHE A 153
THR A  79
 None
 1.01A 5v0vA-1psqA:
undetectable		 5v0vA-1psqA:
13.38