SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pss'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 5 THR L 226
HIS M 266
HIS L 230
HIS L 190
 U10  L 272 (-4.2A)
FE  M 302 (-3.3A)
FE  M 302 (-3.4A)
FE  M 302 ( 3.3A)
 1.24A 1ei6A-1pssL:
undetectable		 1ei6A-1pssL:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 5 GLY L  84
ILE L  88
TRP L  86
VAL L  66
 None
 1.10A 1rs7A-1pssL:
undetectable		 1rs7A-1pssL:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 6 GLY L  84
ILE L  88
TRP L  86
VAL L  66
 None
 1.10A 1rs7B-1pssL:
1.3		 1rs7B-1pssL:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 TYR M 198
TRP L 151
THR L 152
LEU L  63
 None
 1.25A 1uw6A-1pssM:
undetectable
1uw6B-1pssM:
undetectable		 1uw6A-1pssM:
20.20
1uw6B-1pssM:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 TYR M 198
TRP L 151
THR L 152
LEU L  63
 None
 1.28A 1uw6D-1pssM:
undetectable
1uw6E-1pssM:
undetectable		 1uw6D-1pssM:
20.20
1uw6E-1pssM:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 TYR M 198
TRP L 151
THR L 152
LEU L  63
 None
 1.27A 1uw6G-1pssM:
undetectable
1uw6H-1pssM:
undetectable		 1uw6G-1pssM:
20.20
1uw6H-1pssM:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 TYR M 198
TRP L 151
THR L 152
LEU L  63
 None
 1.24A 1uw6P-1pssM:
0.0
1uw6Q-1pssM:
0.0		 1uw6P-1pssM:
20.20
1uw6Q-1pssM:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 LEU L  63
TYR M 198
TRP L 151
THR L 152
 None
 1.25A 1uw6P-1pssL:
undetectable
1uw6T-1pssL:
undetectable		 1uw6P-1pssL:
19.49
1uw6T-1pssL:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 5 LEU L 246
PRO L 171
ALA L 172
ILE L 250
 None
 0.92A 2aofB-1pssL:
undetectable		 2aofB-1pssL:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		3 / 3 TRP M  75
GLN M  77
TRP L 266
 CRT  M 304 (-4.4A)
None
None
 1.19A 2vqyA-1pssM:
undetectable		 2vqyA-1pssM:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		4 / 4 HIS L 190
HIS M 219
HIS M 266
HIS L 230
 FE  M 302 ( 3.3A)
FE  M 302 ( 3.3A)
FE  M 302 (-3.3A)
FE  M 302 (-3.4A)
 1.01A 2wkoA-1pssL:
undetectable		 2wkoA-1pssL:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		4 / 4 HIS M 219
HIS L 190
HIS L 230
HIS M 266
 FE  M 302 ( 3.3A)
FE  M 302 ( 3.3A)
FE  M 302 (-3.4A)
FE  M 302 (-3.3A)
 0.96A 2wkoA-1pssM:
undetectable		 2wkoA-1pssM:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		4 / 5 HIS M 219
HIS L 190
HIS L 230
HIS M 266
 FE  M 302 ( 3.3A)
FE  M 302 ( 3.3A)
FE  M 302 (-3.4A)
FE  M 302 (-3.3A)
 1.01A 2wkoF-1pssM:
undetectable		 2wkoF-1pssM:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 7 GLY M  56
ILE M  50
ARG M 132
LEU M  60
 None
U10  L 272 ( 4.8A)
None
None
 0.96A 2xrhA-1pssM:
undetectable		 2xrhA-1pssM:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 11 THR M 222
ILE M 223
GLY M 220
HIS M 266
ILE M 265
 U10  M 303 (-3.5A)
None
None
FE  M 302 (-3.3A)
U10  M 303 (-4.3A)
 1.29A 2y7kA-1pssM:
undetectable		 2y7kA-1pssM:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1304_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 10 THR M 222
ILE M 223
GLY M 220
HIS M 266
ILE M 265
 U10  M 303 (-3.5A)
None
None
FE  M 302 (-3.3A)
U10  M 303 (-4.3A)
 1.25A 2y7kB-1pssM:
undetectable		 2y7kB-1pssM:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 12 THR M 222
ILE M 223
GLY M 220
HIS M 266
ILE M 265
 U10  M 303 (-3.5A)
None
None
FE  M 302 (-3.3A)
U10  M 303 (-4.3A)
 1.21A 2y7kC-1pssM:
undetectable		 2y7kC-1pssM:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 12 THR M 222
ILE M 223
GLY M 220
HIS M 266
ILE M 265
 U10  M 303 (-3.5A)
None
None
FE  M 302 (-3.3A)
U10  M 303 (-4.3A)
 1.18A 2y7kD-1pssM:
undetectable		 2y7kD-1pssM:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 10 THR M 222
ILE M 223
GLY M 220
HIS M 266
ILE M 265
 U10  M 303 (-3.5A)
None
None
FE  M 302 (-3.3A)
U10  M 303 (-4.3A)
 1.33A 2y7pA-1pssM:
undetectable		 2y7pA-1pssM:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 9 THR M 222
ILE M 223
GLY M 220
HIS M 266
ILE M 265
 U10  M 303 (-3.5A)
None
None
FE  M 302 (-3.3A)
U10  M 303 (-4.3A)
 1.09A 2y7wA-1pssM:
undetectable		 2y7wA-1pssM:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 10 THR M 222
ILE M 223
GLY M 220
HIS M 266
ILE M 265
 U10  M 303 (-3.5A)
None
None
FE  M 302 (-3.3A)
U10  M 303 (-4.3A)
 1.08A 2y7wB-1pssM:
undetectable		 2y7wB-1pssM:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 7 THR M 222
ILE M 223
GLY M 220
HIS M 266
ILE M 265
 U10  M 303 (-3.5A)
None
None
FE  M 302 (-3.3A)
U10  M 303 (-4.3A)
 1.09A 2y7wC-1pssM:
undetectable		 2y7wC-1pssM:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 7 ALA L  93
TYR L 148
ILE L  91
ILE L  89
 BPH  L 271 (-4.0A)
BPH  L 271 ( 4.1A)
None
None
 1.09A 2zm7A-1pssL:
undetectable		 2zm7A-1pssL:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 THR L 182
LEU L 236
ALA L 240
SER L 239
 BCL  M   1 (-3.8A)
None
None
None
 0.75A 3kp6A-1pssL:
undetectable		 3kp6A-1pssL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 5 ILE M 238
HIS M 219
HIS L 190
HIS L 230
 None
FE  M 302 ( 3.3A)
FE  M 302 ( 3.3A)
FE  M 302 (-3.4A)
 0.91A 3ljgA-1pssM:
undetectable		 3ljgA-1pssM:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		3 / 4 SER M 152
GLY L 191
GLU M 263
 BPH  M   5 ( 4.1A)
None
None
 0.54A 3raeA-1pssM:
undetectable
3raeC-1pssM:
undetectable		 3raeA-1pssM:
18.85
3raeC-1pssM:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		3 / 3 PHE L 167
CYH L 247
HIS L 173
 BCL  L   2 (-4.1A)
BCL  L   2 (-3.2A)
BCL  L   2 (-3.7A)
 1.30A 3u9fL-1pssL:
undetectable		 3u9fL-1pssL:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		5 / 12 PHE L 146
TYR M 210
SER L 244
MET L 248
LEU L 131
 BCL  M   4 (-3.5A)
BCL  L   2 (-3.9A)
BCL  L   2 (-3.2A)
BCL  L   2 (-3.4A)
BCL  L   2 ( 4.3A)
 1.32A 4a83A-1pssL:
undetectable		 4a83A-1pssL:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 5 GLY L  84
ILE L  88
TRP L  86
VAL L  66
 None
 0.99A 4d33A-1pssL:
1.3		 4d33A-1pssL:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 5 GLY L  84
ILE L  88
TRP L  86
VAL L  66
 None
 1.03A 4d33B-1pssL:
0.0		 4d33B-1pssL:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 6 GLY L  84
ILE L  88
TRP L  86
VAL L  66
 None
 1.01A 4d39B-1pssL:
0.0		 4d39B-1pssL:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		5 / 12 LEU M 224
GLY L 225
GLN M  11
ARG M  13
ILE L 224
 None
U10  L 272 (-4.3A)
None
None
U10  L 272 (-4.4A)
 1.22A 4djeA-1pssM:
undetectable		 4djeA-1pssM:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 7 ASN L 183
ALA M 213
VAL L 241
ILE L 117
 None
BPH  L 271 ( 3.7A)
BPH  L 271 (-4.3A)
BPH  L 271 (-4.9A)
 0.77A 4eyrA-1pssL:
undetectable		 4eyrA-1pssL:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		3 / 4 SER M 152
GLY L 191
GLU M 263
 BPH  M   5 ( 4.1A)
None
None
 0.55A 4juoA-1pssM:
0.0
4juoC-1pssM:
undetectable		 4juoA-1pssM:
18.85
4juoC-1pssM:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 6 GLY L  84
ILE L  88
TRP L  86
VAL L  66
 None
 1.10A 4kcnA-1pssL:
undetectable		 4kcnA-1pssL:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_H_RFPH1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 12 HIS L 230
ARG L 217
ASN M  44
ILE L 224
ARG L 231
 FE  M 302 (-3.4A)
None
None
U10  L 272 (-4.4A)
None
 1.40A 4kmuH-1pssL:
0.8		 4kmuH-1pssL:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 ALA M 273
PHE M 150
THR M 133
PHE L 215
 BPH  M   5 (-4.2A)
BPH  M   5 (-3.7A)
BPH  M   5 ( 4.2A)
None
 1.00A 4ltwA-1pssM:
undetectable		 4ltwA-1pssM:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 LEU L 189
ILE M 270
VAL M 276
THR M 277
 U10  L 272 ( 4.1A)
None
None
BPH  M   5 (-3.3A)
 0.96A 4ma7A-1pssL:
undetectable		 4ma7A-1pssL:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 6 LEU M 224
HIS L 190
HIS M 266
GLU M 234
 None
FE  M 302 ( 3.3A)
FE  M 302 (-3.3A)
FE  M 302 (-1.9A)
 1.10A 4pahA-1pssM:
undetectable		 4pahA-1pssM:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 7 ILE L  88
LEU L  85
GLY L  83
GLY L  84
 None
 0.83A 5a06A-1pssL:
undetectable		 5a06A-1pssL:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 7 ILE L  88
LEU L  85
GLY L  83
GLY L  84
 None
 0.82A 5a06C-1pssL:
undetectable		 5a06C-1pssL:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 7 ILE L  88
LEU L  85
GLY L  83
GLY L  84
 None
 0.83A 5a06E-1pssL:
undetectable		 5a06E-1pssL:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 7 ILE L  88
LEU L  85
GLY L  83
GLY L  84
 None
 0.81A 5a06F-1pssL:
undetectable		 5a06F-1pssL:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 PHE L 215
GLU L 212
HIS M 266
THR L 182
 None
U10  L 272 (-3.8A)
FE  M 302 (-3.3A)
BCL  M   1 (-3.8A)
 1.38A 5hqaA-1pssL:
undetectable		 5hqaA-1pssL:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 HIS L 230
HIS L 190
LEU L 187
GLY L 191
 FE  M 302 (-3.4A)
FE  M 302 ( 3.3A)
None
None
 0.86A 5m8rC-1pssL:
undetectable		 5m8rC-1pssL:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 GLU L 106
VAL L  36
GLY L  19
LEU L  21
 None
U10  M 303 (-3.9A)
None
None
 1.02A 5sxqB-1pssL:
0.4		 5sxqB-1pssL:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 GLU L 106
VAL L  36
GLY L  19
LEU L  21
 None
U10  M 303 (-3.9A)
None
None
 1.03A 5syjA-1pssL:
0.7		 5syjA-1pssL:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 12 LEU L 193
HIS L 230
ASN M  44
ILE L 224
ARG L 231
 U10  L 272 (-3.8A)
FE  M 302 (-3.4A)
None
U10  L 272 (-4.4A)
None
 1.31A 5uhbC-1pssL:
undetectable		 5uhbC-1pssL:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 12 LEU L 193
HIS L 230
ASN M  44
ILE L 224
ARG L 231
 U10  L 272 (-3.8A)
FE  M 302 (-3.4A)
None
U10  L 272 (-4.4A)
None
 1.23A 5uhcC-1pssL:
1.5		 5uhcC-1pssL:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHD_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 12 LEU L 193
HIS L 230
ASN M  44
ILE L 224
ARG L 231
 U10  L 272 (-3.8A)
FE  M 302 (-3.4A)
None
U10  L 272 (-4.4A)
None
 1.25A 5uhdC-1pssL:
0.0		 5uhdC-1pssL:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHG_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 12 LEU L 193
HIS L 230
ASN M  44
ILE L 224
ARG L 231
 U10  L 272 (-3.8A)
FE  M 302 (-3.4A)
None
U10  L 272 (-4.4A)
None
 1.17A 5uhgC-1pssL:
undetectable		 5uhgC-1pssL:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		5 / 12 LEU L 195
GLY L 191
VAL L 194
ALA L 198
GLY M 264
 None
 0.98A 5xv7A-1pssL:
undetectable		 5xv7A-1pssL:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		4 / 4 HIS M 219
HIS M 266
HIS L 190
HIS L 230
 FE  M 302 ( 3.3A)
FE  M 302 (-3.3A)
FE  M 302 ( 3.3A)
FE  M 302 (-3.4A)
 1.16A 5zrdC-1pssM:
undetectable		 5zrdC-1pssM:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		4 / 4 HIS M 219
HIS M 266
HIS L 190
HIS L 230
 FE  M 302 ( 3.3A)
FE  M 302 (-3.3A)
FE  M 302 ( 3.3A)
FE  M 302 (-3.4A)
 1.16A 5zrdD-1pssM:
undetectable		 5zrdD-1pssM:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		5 / 12 LEU L 232
ILE L 224
LEU M  39
GLY M  40
PHE M  42
 None
U10  L 272 (-4.4A)
None
None
None
 1.08A 6qxsB-1pssL:
0.0		 6qxsB-1pssL:
21.86