SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1psw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II
(Escherichia
coli) 		5 / 10 GLY A 184
TRP A 197
LEU A 209
LEU A 205
TYR A 202
 None
 1.39A 1pbcA-1pswA:
3.4		 1pbcA-1pswA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II
(Escherichia
coli) 		3 / 3 GLU A 190
TRP A  10
LYS A 167
 None
 1.25A 1qu2A-1pswA:
1.5		 1qu2A-1pswA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II
(Escherichia
coli) 		4 / 7 LEU A 130
THR A 295
PRO A 296
GLY A  12
 None
 0.89A 2ddwB-1pswA:
undetectable		 2ddwB-1pswA:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II
(Escherichia
coli) 		3 / 3 ARG A 303
GLU A 347
SER A 299
 None
 0.91A 2xkkA-1pswA:
2.5
2xkkC-1pswA:
undetectable		 2xkkA-1pswA:
19.14
2xkkC-1pswA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II
(Escherichia
coli) 		4 / 4 SER A 270
GLY A 271
GLY A 188
GLY A 220
 None
 0.67A 3bogB-1pswA:
undetectable
3bogD-1pswA:
0.0		 3bogB-1pswA:
undetectable
3bogD-1pswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II
(Escherichia
coli) 		3 / 3 PRO A 154
LEU A 155
GLN A 153
 None
 0.61A 3hznG-1pswA:
undetectable
3hznH-1pswA:
undetectable		 3hznG-1pswA:
19.03
3hznH-1pswA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II
(Escherichia
coli) 		4 / 7 ILE A  33
LEU A  24
LEU A 138
SER A  93
 None
 0.95A 3r9vA-1pswA:
undetectable
3r9vB-1pswA:
undetectable		 3r9vA-1pswA:
23.01
3r9vB-1pswA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II
(Escherichia
coli) 		4 / 6 LEU A 116
PHE A  91
LEU A  95
PHE A  99
 None
 0.99A 3wg7C-1pswA:
undetectable
3wg7J-1pswA:
undetectable		 3wg7C-1pswA:
20.40
3wg7J-1pswA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II
(Escherichia
coli) 		4 / 7 ASN A  89
SER A  93
ILE A   6
PRO A   8
 None
 0.99A 5u4sA-1pswA:
5.8		 5u4sA-1pswA:
21.49