SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pu7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 5 PHE A 174
LEU A   2
PHE A 202
SER A  13
 None
 1.27A 1wrlC-1pu7A:
undetectable		 1wrlC-1pu7A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 6 LEU A  97
LEU A 100
LEU A  69
LEU A  61
 None
 0.89A 2ab2A-1pu7A:
undetectable		 2ab2A-1pu7A:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		3 / 3 PHE A 174
SER A 210
LEU A 155
 None
 0.80A 2w1bA-1pu7A:
undetectable		 2w1bA-1pu7A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		3 / 3 GLU A   6
GLU A 180
ASN A 181
 None
 0.78A 3lp9B-1pu7A:
undetectable
3lp9D-1pu7A:
undetectable		 3lp9B-1pu7A:
24.25
3lp9D-1pu7A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		5 / 12 ILE A 104
LEU A  69
ILE A  72
ALA A  73
ILE A 129
 None
 1.06A 3vrmA-1pu7A:
0.0		 3vrmA-1pu7A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 8 ASP A 135
ASP A 166
GLU A 121
GLU A 175
 None
 1.05A 4feuF-1pu7A:
undetectable		 4feuF-1pu7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 7 ASP A 135
ASP A 166
GLU A 121
GLU A 175
 None
 1.16A 4fevB-1pu7A:
undetectable		 4fevB-1pu7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 7 ASP A 135
ASP A 166
GLU A 121
GLU A 175
 None
 1.03A 4fevF-1pu7A:
undetectable		 4fevF-1pu7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 7 ASP A 135
ASP A 166
GLU A 121
GLU A 175
 None
 1.18A 4fewB-1pu7A:
undetectable		 4fewB-1pu7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 7 ASP A 135
ASP A 166
GLU A 121
GLU A 175
 None
 0.98A 4fexB-1pu7A:
undetectable		 4fexB-1pu7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 8 ASP A 135
ASP A 166
GLU A 121
GLU A 175
 None
 0.92A 4gkhB-1pu7A:
undetectable		 4gkhB-1pu7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 8 ASP A 135
ASP A 166
GLU A 121
GLU A 175
 None
 1.15A 4gkhD-1pu7A:
undetectable		 4gkhD-1pu7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 8 ASP A 135
ASP A 166
GLU A 121
GLU A 175
 None
 0.81A 4gkiC-1pu7A:
0.0		 4gkiC-1pu7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 6 PRO A  86
VAL A  38
PHE A  45
THR A  43
 None
None
39A  A 219 (-3.5A)
None
 1.18A 4xe5A-1pu7A:
undetectable		 4xe5A-1pu7A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		4 / 5 TYR A 140
LEU A  17
PRO A  21
LEU A 198
 None
KCX  A 205 ( 4.1A)
None
None
 1.47A 5eshA-1pu7A:
0.0		 5eshA-1pu7A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1pu7 3-METHYLADENINE DNA
GLYCOSYLASE
(Helicobacter
pylori) 		6 / 11 LEU A 100
ASP A  99
ILE A  98
ILE A 129
GLY A 128
VAL A  38
 None
 1.28A 5twjD-1pu7A:
undetectable		 5twjD-1pu7A:
19.27