SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pui'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 1pui PROBABLE GTP-BINDING
PROTEIN ENGB
(Escherichia
coli) 		5 / 12 ILE A  18
LEU A 109
LEU A  99
GLY A 100
ALA A  32
 None
 0.86A 1hvyD-1puiA:
0.0		 1hvyD-1puiA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 1pui PROBABLE GTP-BINDING
PROTEIN ENGB
(Escherichia
coli) 		5 / 12 PHE A  31
LEU A  79
ALA A  32
LEU A 103
LEU A 193
 None
 1.05A 1og5A-1puiA:
undetectable		 1og5A-1puiA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 1pui PROBABLE GTP-BINDING
PROTEIN ENGB
(Escherichia
coli) 		3 / 3 ASP A  24
SER A 108
ARG A  75
 None
 0.97A 3loqA-1puiA:
4.5		 3loqA-1puiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 1pui PROBABLE GTP-BINDING
PROTEIN ENGB
(Escherichia
coli) 		4 / 8 LEU A 112
ALA A  98
VAL A 140
TYR A  82
 None
 1.03A 5nu7A-1puiA:
undetectable		 5nu7A-1puiA:
22.97