SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1puo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 1puo MAJOR ALLERGEN I
POLYPEPTIDE, FUSED
CHAIN 2, CHAIN 1
(Felis
catus) 		4 / 4 VAL A  13
ALA A  16
ASN A  21
GLN A  46
 None
 0.85A 4zgfA-1puoA:
undetectable		 4zgfA-1puoA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1puo MAJOR ALLERGEN I
POLYPEPTIDE, FUSED
CHAIN 2, CHAIN 1
(Felis
catus) 		5 / 12 ASP A 138
ALA A 130
TYR A 113
LEU A 127
VAL A 117
 None
 1.26A 5hw4A-1puoA:
undetectable		 5hw4A-1puoA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1puo MAJOR ALLERGEN I
POLYPEPTIDE, FUSED
CHAIN 2, CHAIN 1
(Felis
catus) 		5 / 11 ASP A 138
ALA A 130
TYR A 113
LEU A 127
VAL A 117
 None
 1.27A 5hw4B-1puoA:
undetectable		 5hw4B-1puoA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1puo MAJOR ALLERGEN I
POLYPEPTIDE, FUSED
CHAIN 2, CHAIN 1
(Felis
catus) 		4 / 5 VAL A 137
PRO A 110
GLY A 108
TYR A 113
 None
 1.18A 5x80A-1puoA:
2.3
5x80B-1puoA:
1.7		 5x80A-1puoA:
26.14
5x80B-1puoA:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1puo MAJOR ALLERGEN I
POLYPEPTIDE, FUSED
CHAIN 2, CHAIN 1
(Felis
catus) 		4 / 5 PRO A 110
GLY A 108
TYR A 113
VAL A 137
 None
 1.09A 5x80C-1puoA:
1.7
5x80D-1puoA:
1.6		 5x80C-1puoA:
26.14
5x80D-1puoA:
26.14