SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		4 / 7 MET A  60
TYR A  86
LEU A  83
GLN A  84
 None
 1.07A 1kt3A-1pv5A:
0.0		 1kt3A-1pv5A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		5 / 11 GLY A 197
GLY A 196
ILE A 195
VAL A 254
ILE A 241
 None
 0.80A 1sduA-1pv5A:
undetectable		 1sduA-1pv5A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		5 / 11 SER A 252
VAL A 254
ILE A 241
LEU A 218
LEU A  83
 None
 1.29A 2a15A-1pv5A:
undetectable		 2a15A-1pv5A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		3 / 3 LEU A   4
ASN A   2
ARG A  12
 None
 0.97A 2qhfA-1pv5A:
0.0		 2qhfA-1pv5A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMQ_A_BEZA3_0
(PROTEIN NDRG2)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		4 / 7 TYR A 198
TYR A 163
GLN A 162
PHE A 160
 None
 1.13A 2qmqA-1pv5A:
0.0		 2qmqA-1pv5A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		5 / 8 LYS A 194
LEU A 219
GLN A 220
PHE A  85
PHE A  68
 None
 1.35A 3asoC-1pv5A:
undetectable
3asoJ-1pv5A:
undetectable		 3asoC-1pv5A:
20.51
3asoJ-1pv5A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		3 / 3 CYH A 134
PRO A 137
ASP A  91
 None
 0.98A 3hlwB-1pv5A:
undetectable		 3hlwB-1pv5A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		3 / 3 THR A 164
LYS A 194
GLU A 161
 None
 0.71A 3ijdB-1pv5A:
undetectable		 3ijdB-1pv5A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		4 / 5 THR A 168
VAL A 153
PRO A 155
TYR A 183
 None
 1.08A 4grkA-1pv5A:
undetectable		 4grkA-1pv5A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		4 / 7 PHE A 175
PRO A 155
TYR A 183
PHE A 160
 None
 1.22A 4grqA-1pv5A:
0.0
4grqC-1pv5A:
0.0		 4grqA-1pv5A:
19.48
4grqC-1pv5A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		3 / 3 CYH A 134
PRO A 137
ASP A  91
 None
 0.98A 4pm5A-1pv5A:
undetectable		 4pm5A-1pv5A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		4 / 8 ILE A  66
PRO A  78
PHE A 251
LEU A 246
 None
 0.91A 4qopC-1pv5A:
undetectable		 4qopC-1pv5A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		4 / 6 PRO A 155
ILE A 182
THR A 164
ARG A  12
 None
 1.16A 4xe5A-1pv5A:
undetectable		 4xe5A-1pv5A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		4 / 4 LEU A  25
ILE A  39
HIS A 193
VAL A 144
 None
 1.09A 4xyzA-1pv5A:
undetectable		 4xyzA-1pv5A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		4 / 4 TYR A 111
ASN A  67
SER A  69
SER A  80
 None
 1.30A 5gsnC-1pv5A:
0.0		 5gsnC-1pv5A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		5 / 9 THR A 156
ASP A 157
GLY A 190
PHE A 191
PHE A 240
 None
 1.15A 6ebpA-1pv5A:
undetectable		 6ebpA-1pv5A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		5 / 10 THR A 156
ASP A 157
GLY A 190
PHE A 191
PHE A 240
 None
 1.14A 6ebpB-1pv5A:
undetectable		 6ebpB-1pv5A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		5 / 10 THR A 156
ASP A 157
GLY A 190
PHE A 191
PHE A 240
 None
 1.14A 6ebpC-1pv5A:
undetectable		 6ebpC-1pv5A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 1pv5 HYPOTHETICAL PROTEIN
YWQG
(Bacillus
subtilis) 		4 / 4 LEU A 255
ASP A 205
PRO A 206
ARG A 207
 None
 1.03A 6fgdA-1pv5A:
undetectable		 6fgdA-1pv5A:
20.32