SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pvm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1pvm CONSERVED
HYPOTHETICAL PROTEIN
TA0289
(Thermoplasma
acidophilum) 		4 / 4 ILE A 164
ARG A  62
ASP A 141
ASN A  98
 None
 1.45A 1nbiC-1pvmA:
0.0		 1nbiC-1pvmA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1pvm CONSERVED
HYPOTHETICAL PROTEIN
TA0289
(Thermoplasma
acidophilum) 		4 / 7 LEU A 100
TYR A 142
VAL A  69
ILE A  55
 None
 1.29A 3ik3A-1pvmA:
undetectable		 3ik3A-1pvmA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1pvm CONSERVED
HYPOTHETICAL PROTEIN
TA0289
(Thermoplasma
acidophilum) 		3 / 3 VAL A  74
SER A  54
LEU A  50
 None
 0.75A 3n8xA-1pvmA:
undetectable		 3n8xA-1pvmA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 1pvm CONSERVED
HYPOTHETICAL PROTEIN
TA0289
(Thermoplasma
acidophilum) 		3 / 3 VAL A 113
ALA A 104
PHE A  13
 None
 0.89A 4olbA-1pvmA:
undetectable		 4olbA-1pvmA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1pvm CONSERVED
HYPOTHETICAL PROTEIN
TA0289
(Thermoplasma
acidophilum) 		3 / 3 VAL A 113
ALA A 104
PHE A  13
 None
 0.90A 4w5nA-1pvmA:
undetectable		 4w5nA-1pvmA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1pvm CONSERVED
HYPOTHETICAL PROTEIN
TA0289
(Thermoplasma
acidophilum) 		4 / 7 LEU A 100
PRO A  80
LEU A  95
TYR A  94
 None
 0.85A 4z4fA-1pvmA:
undetectable		 4z4fA-1pvmA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1pvm CONSERVED
HYPOTHETICAL PROTEIN
TA0289
(Thermoplasma
acidophilum) 		3 / 3 VAL A 113
ALA A 104
PHE A  13
 None
 0.88A 4z4iA-1pvmA:
undetectable		 4z4iA-1pvmA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1pvm CONSERVED
HYPOTHETICAL PROTEIN
TA0289
(Thermoplasma
acidophilum) 		3 / 3 VAL A 113
ALA A 104
PHE A  13
 None
 0.86A 5js1A-1pvmA:
undetectable		 5js1A-1pvmA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1pvm CONSERVED
HYPOTHETICAL PROTEIN
TA0289
(Thermoplasma
acidophilum) 		4 / 7 LEU A 100
PRO A  80
LEU A  95
TYR A  94
 None
 0.91A 5t7bA-1pvmA:
undetectable		 5t7bA-1pvmA:
11.96