SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pvx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		5 / 10 GLY A  48
ASN A  29
TYR A  15
THR A 177
GLY A  47
 None
 0.94A 1kvlA-1pvxA:
undetectable		 1kvlA-1pvxA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		4 / 7 LEU A 105
LEU A 117
SER A 139
VAL A  85
 None
 0.92A 1tyrB-1pvxA:
0.0		 1tyrB-1pvxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		4 / 7 LEU A 105
LEU A 117
SER A 139
VAL A  85
 None
 0.75A 3d2tA-1pvxA:
undetectable		 3d2tA-1pvxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		4 / 8 GLY A  21
GLY A  22
GLY A  42
SER A  19
 None
 0.64A 3d41A-1pvxA:
undetectable		 3d41A-1pvxA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		5 / 12 ALA A 176
GLY A 179
ILE A 188
SER A  75
LEU A  74
 None
 1.25A 3gyqA-1pvxA:
undetectable
3gyqB-1pvxA:
undetectable		 3gyqA-1pvxA:
19.41
3gyqB-1pvxA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		3 / 3 TYR A 115
PHE A  62
ARG A 141
 None
 1.08A 4g19D-1pvxA:
undetectable		 4g19D-1pvxA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		4 / 4 THR A  71
GLY A  43
ASP A  20
SER A 182
 None
 1.22A 4rfqA-1pvxA:
undetectable		 4rfqA-1pvxA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		4 / 6 SER A  16
GLU A   7
GLY A  43
GLY A  21
 None
 0.91A 5cdpA-1pvxA:
undetectable
5cdpB-1pvxA:
undetectable		 5cdpA-1pvxA:
16.77
5cdpB-1pvxA:
16.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		6 / 12 VAL A  46
TRP A  79
TYR A  88
PRO A 126
TRP A 138
TYR A 172
 None
 0.69A 5tzoA-1pvxA:
27.1		 5tzoA-1pvxA:
45.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		5 / 12 VAL A  46
TRP A  79
TYR A  88
TRP A 138
TYR A 172
 None
 0.71A 5tzoB-1pvxA:
27.1		 5tzoB-1pvxA:
45.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		3 / 3 ARG A 122
PRO A 126
TYR A 180
 None
 0.88A 5tzoB-1pvxA:
27.1		 5tzoB-1pvxA:
45.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		5 / 12 TRP A  79
TYR A  88
PRO A 126
TRP A 138
TYR A 172
 None
 0.56A 5tzoC-1pvxA:
27.0		 5tzoC-1pvxA:
45.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)
(Byssochlamys
spectabilis) 		5 / 12 VAL A  46
TRP A  79
TYR A  88
PRO A 126
TRP A 138
 None
 0.57A 5tzoC-1pvxA:
27.0		 5tzoC-1pvxA:
45.41