SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pwo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		4 / 4 LEU A   2
GLY A  30
ASP A  49
TYR A  69
 None
 0.73A 1oxrA-1pwoA:
20.3		 1oxrA-1pwoA:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		4 / 8 LEU A   2
GLY A  30
HIS A  48
PHE A 106
 None
 0.82A 1sv9A-1pwoA:
17.6		 1sv9A-1pwoA:
36.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD7_A_NFLA2001_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		6 / 9 LEU A   2
ILE A   9
PHE A  22
GLY A  30
TYR A  69
PHE A 106
 None
 0.62A 1td7A-1pwoA:
20.2		 1td7A-1pwoA:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.74A 1th6A-1pwoA:
17.6		 1th6A-1pwoA:
36.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.73A 2armA-1pwoA:
17.6		 2armA-1pwoA:
36.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		6 / 11 ILE A   9
ILE A  13
TYR A  25
GLY A  30
LEU A  41
PHE A 106
 None
 0.38A 2azyA-1pwoA:
18.5		 2azyA-1pwoA:
56.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		6 / 11 ILE A   9
ILE A  13
TYR A  25
GLY A  30
LEU A  41
TYR A 111
 None
 0.72A 2azyA-1pwoA:
18.5		 2azyA-1pwoA:
56.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		5 / 10 LEU A   2
GLY A  30
HIS A  48
ASP A  49
PHE A 106
 None
 0.86A 2b17A-1pwoA:
17.6		 2b17A-1pwoA:
36.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		4 / 6 LEU A   2
HIS A  48
ASP A  49
TYR A  52
 None
 0.74A 2dpzA-1pwoA:
17.9		 2dpzA-1pwoA:
36.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		4 / 4 ASP A  42
ASP A  49
ASP A  24
GLY A  33
 None
 1.11A 2igtC-1pwoA:
undetectable		 2igtC-1pwoA:
17.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.65A 3fo7A-1pwoA:
17.6		 3fo7A-1pwoA:
36.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.58A 3h1xA-1pwoA:
17.7		 3h1xA-1pwoA:
36.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		7 / 9 LEU A   2
PHE A   5
ILE A   9
PHE A  22
GLY A  30
HIS A  48
TYR A  69
 None
 0.49A 3oshA-1pwoA:
20.2		 3oshA-1pwoA:
59.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1pwo PHOSPHOLIPASE A2
(Micropechis
ikaheca) 		6 / 9 PHE A   5
ILE A   9
PHE A  22
GLY A  30
LYS A  31
HIS A  48
 None
 0.80A 3oshA-1pwoA:
20.2		 3oshA-1pwoA:
59.20