SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pww'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 ILE A 225
LEU A 155
GLY A 152
TYR A  74
VAL A  70
 None
 1.32A 1axwB-1pwwA:
undetectable		 1axwB-1pwwA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 ILE A 225
ALA A 144
ILE A  81
LEU A  71
ILE A 151
 None
 1.08A 1dhiB-1pwwA:
undetectable		 1dhiB-1pwwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 8 ALA A 220
LEU A 189
LEU A 233
ALA A 237
 None
 0.77A 1e7cA-1pwwA:
undetectable		 1e7cA-1pwwA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 LEU A 155
LEU A  71
ILE A  77
GLY A  79
LEU A 129
 None
 1.16A 1g50B-1pwwA:
0.7		 1g50B-1pwwA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 LEU A 155
LEU A  71
ILE A  77
GLY A  79
LEU A 129
 None
 1.16A 1g50C-1pwwA:
0.5		 1g50C-1pwwA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 7 LEU A 505
THR A 509
GLY A 428
TYR A 278
 None
 0.90A 1gtiB-1pwwA:
0.0		 1gtiB-1pwwA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 6 TRP A 570
LEU A 574
LEU A 576
PRO A 577
 None
 1.33A 1hz4A-1pwwA:
undetectable		 1hz4A-1pwwA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 THR A 191
GLY A 109
ASP A 106
ILE A 104
ALA A 121
 None
 1.38A 1oltA-1pwwA:
undetectable		 1oltA-1pwwA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 8 PHE A 629
LEU A 603
TRP A 606
THR A 584
 None
 0.86A 1rmtD-1pwwA:
undetectable		 1rmtD-1pwwA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 6 PRO A 127
PHE A 217
LEU A 155
ILE A 159
 None
 1.20A 1sbrA-1pwwA:
undetectable
1sbrB-1pwwA:
0.0		 1sbrA-1pwwA:
13.55
1sbrB-1pwwA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 7 ARG A 742
THR A 731
GLY A 729
TYR A 728
 None
 1.04A 2f6dA-1pwwA:
undetectable		 2f6dA-1pwwA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 6 LEU A  63
VAL A  66
ILE A 151
MET A  40
ILE A  81
 None
 1.39A 2piwA-1pwwA:
undetectable		 2piwA-1pwwA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 10 PHE A 688
ILE A 666
GLY A 683
PHE A 684
TYR A 728
 None
 1.33A 2tsrC-1pwwA:
0.0		 2tsrC-1pwwA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 ILE A 107
ASP A 184
ALA A 240
HIS A 229
LEU A 233
 None
 0.96A 2yqzA-1pwwA:
undetectable		 2yqzA-1pwwA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 10 LEU A 129
ILE A 151
SER A 156
LYS A 153
GLY A 152
 None
 1.30A 3ik6B-1pwwA:
undetectable
3ik6E-1pwwA:
undetectable		 3ik6B-1pwwA:
17.43
3ik6E-1pwwA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 ILE A 151
SER A 156
LYS A 153
GLY A 152
LEU A 129
 None
 1.37A 3iluB-1pwwA:
0.0
3iluE-1pwwA:
0.0		 3iluB-1pwwA:
17.43
3iluE-1pwwA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		3 / 4 SER A 598
GLY A 657
GLU A 739
 None
 0.57A 3raeA-1pwwA:
undetectable
3raeC-1pwwA:
undetectable		 3raeA-1pwwA:
20.69
3raeC-1pwwA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 5 ILE A 525
SER A 553
LYS A 552
GLY A 526
 None
 0.79A 3tkdA-1pwwA:
undetectable		 3tkdA-1pwwA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 HIS A 686
TYR A 728
GLU A 735
HIS A 690
CYH A 687
 ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
ZN  A9001 (-3.3A)
None
 1.02A 4ir0A-1pwwA:
undetectable
4ir0B-1pwwA:
undetectable		 4ir0A-1pwwA:
11.52
4ir0B-1pwwA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 HIS A 690
CYH A 687
HIS A 686
TYR A 728
GLU A 735
 ZN  A9001 (-3.3A)
None
ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
 1.06A 4ir0A-1pwwA:
undetectable
4ir0B-1pwwA:
undetectable		 4ir0A-1pwwA:
11.52
4ir0B-1pwwA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 HIS A 686
TYR A 728
GLU A 735
HIS A 690
CYH A 687
 ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
ZN  A9001 (-3.3A)
None
 0.96A 4jd1A-1pwwA:
undetectable
4jd1B-1pwwA:
undetectable		 4jd1A-1pwwA:
11.52
4jd1B-1pwwA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 HIS A 690
CYH A 687
HIS A 686
TYR A 728
GLU A 735
 ZN  A9001 (-3.3A)
None
ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
 1.12A 4jd1A-1pwwA:
undetectable
4jd1B-1pwwA:
undetectable		 4jd1A-1pwwA:
11.52
4jd1B-1pwwA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 HIS A 686
TYR A 728
GLU A 735
HIS A 690
CYH A 687
 ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
ZN  A9001 (-3.3A)
None
 1.05A 4jh3A-1pwwA:
undetectable
4jh3B-1pwwA:
undetectable		 4jh3A-1pwwA:
10.32
4jh3B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 HIS A 690
CYH A 687
HIS A 686
TYR A 728
GLU A 735
 ZN  A9001 (-3.3A)
None
ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
 1.05A 4jh3A-1pwwA:
undetectable
4jh3B-1pwwA:
undetectable		 4jh3A-1pwwA:
10.32
4jh3B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 HIS A 686
TYR A 728
GLU A 735
HIS A 690
CYH A 687
 ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
ZN  A9001 (-3.3A)
None
 1.01A 4jh4A-1pwwA:
undetectable
4jh4B-1pwwA:
undetectable		 4jh4A-1pwwA:
10.32
4jh4B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 HIS A 690
CYH A 687
HIS A 686
TYR A 728
GLU A 735
 ZN  A9001 (-3.3A)
None
ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
 1.04A 4jh4A-1pwwA:
undetectable
4jh4B-1pwwA:
undetectable		 4jh4A-1pwwA:
10.32
4jh4B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 HIS A 686
TYR A 728
GLU A 735
HIS A 690
CYH A 687
 ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
ZN  A9001 (-3.3A)
None
 1.02A 4jh5A-1pwwA:
undetectable
4jh5B-1pwwA:
undetectable		 4jh5A-1pwwA:
10.32
4jh5B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 11 HIS A 690
CYH A 687
HIS A 686
TYR A 728
GLU A 735
 ZN  A9001 (-3.3A)
None
ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
 1.01A 4jh5A-1pwwA:
undetectable
4jh5B-1pwwA:
undetectable		 4jh5A-1pwwA:
10.32
4jh5B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 10 HIS A 686
TYR A 728
GLU A 735
HIS A 690
CYH A 687
 ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
ZN  A9001 (-3.3A)
None
 1.06A 4jh6A-1pwwA:
undetectable
4jh6B-1pwwA:
undetectable		 4jh6A-1pwwA:
10.32
4jh6B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 10 HIS A 690
CYH A 687
HIS A 686
TYR A 728
GLU A 735
 ZN  A9001 (-3.3A)
None
ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
 1.06A 4jh6A-1pwwA:
undetectable
4jh6B-1pwwA:
undetectable		 4jh6A-1pwwA:
10.32
4jh6B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 10 HIS A 686
TYR A 728
GLU A 735
HIS A 690
CYH A 687
 ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
ZN  A9001 (-3.3A)
None
 1.05A 4jh8A-1pwwA:
undetectable
4jh8B-1pwwA:
undetectable		 4jh8A-1pwwA:
10.32
4jh8B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 10 HIS A 690
CYH A 687
HIS A 686
TYR A 728
GLU A 735
 ZN  A9001 (-3.3A)
None
ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
 1.07A 4jh8A-1pwwA:
undetectable
4jh8B-1pwwA:
undetectable		 4jh8A-1pwwA:
10.32
4jh8B-1pwwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		3 / 4 SER A 598
GLY A 657
GLU A 739
 None
 0.58A 4juoA-1pwwA:
undetectable
4juoC-1pwwA:
undetectable		 4juoA-1pwwA:
20.69
4juoC-1pwwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 4 ILE A 649
SER A 403
ASP A 382
ASP A 306
 None
 1.24A 4krhB-1pwwA:
undetectable		 4krhB-1pwwA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 9 PHE A 247
ILE A 225
VAL A  66
GLY A 152
VAL A  70
 None
 1.00A 4r20B-1pwwA:
0.0		 4r20B-1pwwA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 ASN A 767
ASP A 768
ALA A 696
VAL A 708
PHE A 714
 None
 1.16A 4u8vB-1pwwA:
undetectable		 4u8vB-1pwwA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 8 ASP A 456
ASP A 459
GLU A 541
ILE A 534
 None
 0.73A 4xjeA-1pwwA:
0.0		 4xjeA-1pwwA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 LEU A 114
ILE A 104
GLU A 212
VAL A 130
LEU A  94
 None
 0.85A 4y0sA-1pwwA:
undetectable		 4y0sA-1pwwA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 5 PHE A 688
PHE A 737
PHE A 741
VAL A 692
 None
 1.17A 5a1rA-1pwwA:
undetectable		 5a1rA-1pwwA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 8 ASP A 456
ASP A 459
GLU A 541
ILE A 534
 None
 0.75A 5cfsA-1pwwA:
0.0		 5cfsA-1pwwA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		3 / 3 TYR A  82
LYS A  80
LYS A  45
 None
 1.06A 5dbyA-1pwwA:
0.0		 5dbyA-1pwwA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 7 PHE A 631
ILE A 602
THR A 619
LEU A 574
 None
 1.03A 5esmA-1pwwA:
0.3		 5esmA-1pwwA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		4 / 4 HIS A 690
HIS A 686
TYR A 728
GLU A 735
 ZN  A9001 (-3.3A)
ZN  A9001 (-3.4A)
None
ZN  A9001 (-2.0A)
 1.38A 5pahA-1pwwA:
undetectable		 5pahA-1pwwA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 10 PHE A 688
ILE A 666
GLY A 683
PHE A 684
TYR A 728
 None
 1.39A 5x66D-1pwwA:
undetectable		 5x66D-1pwwA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 LEU A 188
PRO A 238
ALA A 237
GLU A 249
PHE A 247
 None
 1.09A 5x6yA-1pwwA:
undetectable		 5x6yA-1pwwA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 1pww LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 LEU A 188
PRO A 238
ALA A 237
GLU A 249
PHE A 247
 None
 1.23A 5x6yC-1pwwA:
undetectable		 5x6yC-1pwwA:
21.85