SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1px8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 ARG A 260
ASP A 223
ASN A 192
 None
 0.88A 1nbhA-1px8A:
undetectable		 1nbhA-1px8A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 ARG A 260
ASP A 223
ASN A 192
 None
 0.88A 1nbhD-1px8A:
undetectable		 1nbhD-1px8A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 VAL A 150
ILE A 186
VAL A  61
ILE A  63
ILE A 100
 None
 1.17A 1r5lA-1px8A:
2.0		 1r5lA-1px8A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 PHE A 102
VAL A 114
TRP A 117
 None
 0.86A 2cc8A-1px8A:
0.0		 2cc8A-1px8A:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 PHE A 102
VAL A 114
TRP A 117
 None
 0.85A 2ccbA-1px8A:
0.0		 2ccbA-1px8A:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 11 VAL A  61
TYR A  35
GLY A  28
ASP A  60
THR A  24
 None
 1.49A 2f9wA-1px8A:
undetectable
2f9wB-1px8A:
undetectable		 2f9wA-1px8A:
17.45
2f9wB-1px8A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 TRP A 167
PRO A 123
LEU A 107
GLY A 101
 None
 0.95A 2hs2B-1px8A:
undetectable		 2hs2B-1px8A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 ALA A 447
VAL A 338
PHE A 348
THR A 347
 None
 1.16A 2kotB-1px8A:
0.0		 2kotB-1px8A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 LYS A  13
LEU A 369
MET A 368
ARG A 364
LEU A 479
 None
 1.29A 2lbdA-1px8A:
undetectable		 2lbdA-1px8A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 ALA A 339
ASP A 319
ARG A 444
MET A 429
 None
 1.39A 2ouzA-1px8A:
undetectable		 2ouzA-1px8A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 5 GLU A 149
ILE A 147
GLY A 146
LYS A 152
 None
 1.04A 2qeuA-1px8A:
0.0
2qeuC-1px8A:
0.0		 2qeuA-1px8A:
16.39
2qeuC-1px8A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 LEU A  27
LEU A  56
ILE A  51
ARG A  52
 None
None
None
XYP  A 601 ( 4.9A)
 0.93A 2rlfA-1px8A:
0.0
2rlfB-1px8A:
0.0		 2rlfA-1px8A:
7.14
2rlfB-1px8A:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 LEU A  27
LEU A  56
ILE A  51
ARG A  52
 None
None
None
XYP  A 601 ( 4.9A)
 0.92A 2rlfC-1px8A:
undetectable
2rlfD-1px8A:
undetectable		 2rlfC-1px8A:
7.14
2rlfD-1px8A:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		6 / 12 ASN A 159
GLU A 160
HIS A 228
TYR A 230
GLU A 277
TRP A 315
 XYP  A 601 (-3.1A)
XYP  A 601 (-2.2A)
XYP  A 601 ( 4.8A)
None
XYP  A 601 (-2.7A)
XYP  A 601 (-4.1A)
 0.73A 2v3dA-1px8A:
13.3		 2v3dA-1px8A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		6 / 12 ASN A 159
GLU A 160
PHE A 115
HIS A 228
GLU A 277
TRP A 315
 XYP  A 601 (-3.1A)
XYP  A 601 (-2.2A)
XYP  A 601 (-4.5A)
XYP  A 601 ( 4.8A)
XYP  A 601 (-2.7A)
XYP  A 601 (-4.1A)
 0.76A 2v3dA-1px8A:
13.3		 2v3dA-1px8A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 11 ASN A 159
GLU A 160
PHE A 115
GLU A 277
TRP A 315
 XYP  A 601 (-3.1A)
XYP  A 601 (-2.2A)
XYP  A 601 (-4.5A)
XYP  A 601 (-2.7A)
XYP  A 601 (-4.1A)
 0.68A 2v3dB-1px8A:
18.1		 2v3dB-1px8A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 11 ASN A 159
GLU A 160
TYR A 230
GLU A 277
TRP A 315
 XYP  A 601 (-3.1A)
XYP  A 601 (-2.2A)
None
XYP  A 601 (-2.7A)
XYP  A 601 (-4.1A)
 0.74A 2v3dB-1px8A:
18.1		 2v3dB-1px8A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 PHE A 102
VAL A 114
TRP A 117
 None
 0.83A 2vx9A-1px8A:
0.0		 2vx9A-1px8A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 ILE A 100
LEU A  57
ILE A 186
ILE A  82
PHE A  86
 None
 1.01A 2ygqA-1px8A:
undetectable		 2ygqA-1px8A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 TYR A  50
LEU A  29
ARG A  52
 None
None
XYP  A 601 ( 4.9A)
 0.79A 3sufB-1px8A:
0.0		 3sufB-1px8A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 PHE A 354
PHE A 351
PHE A 353
LEU A 414
ALA A 295
 None
 1.33A 4a83A-1px8A:
0.9		 4a83A-1px8A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 ARG A 227
GLU A 209
ILE A 208
ASN A 162
 None
 0.90A 4d39B-1px8A:
0.0		 4d39B-1px8A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 LEU A 465
TYR A 397
LEU A 380
TYR A 477
 None
 1.16A 4f3tA-1px8A:
0.9		 4f3tA-1px8A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 CYH A  58
ARG A  65
GLY A  62
ILE A  82
LEU A  31
 None
 1.48A 4kosA-1px8A:
1.0		 4kosA-1px8A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOY_A_CSCA214_1
(UNCHARACTERIZED
PROTEIN)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 11 CYH A  58
ARG A  65
GLY A  62
ILE A  82
LEU A  31
 None
 1.46A 4koyA-1px8A:
1.2		 4koyA-1px8A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 GLU A  99
GLU A 160
GLU A 323
TYR A 278
 None
XYP  A 601 (-2.2A)
XYP  A 601 (-2.6A)
None
 0.85A 4mj8A-1px8A:
undetectable
4mj8C-1px8A:
1.2		 4mj8A-1px8A:
17.04
4mj8C-1px8A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 ILE A  82
ILE A  36
ALA A  30
LEU A  27
LEU A  56
 None
 0.89A 4o1zA-1px8A:
undetectable		 4o1zA-1px8A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 VAL A  61
LEU A  29
GLY A  28
ASP A  60
THR A  24
 None
 1.17A 4o5fA-1px8A:
0.8
4o5fB-1px8A:
undetectable		 4o5fA-1px8A:
18.42
4o5fB-1px8A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 THR A  24
VAL A  61
LEU A  29
GLY A  28
ASP A  60
 None
 1.15A 4o5fA-1px8A:
0.8
4o5fB-1px8A:
undetectable		 4o5fA-1px8A:
18.42
4o5fB-1px8A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 VAL A  61
LEU A  29
GLY A  28
ASP A  60
THR A  24
 None
 1.14A 5b8hA-1px8A:
undetectable
5b8hB-1px8A:
undetectable		 5b8hA-1px8A:
19.30
5b8hB-1px8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 GLY A 197
HIS A 274
LEU A 271
GLY A 101
PHE A  97
 None
 1.13A 5d4uA-1px8A:
undetectable		 5d4uA-1px8A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 GLY A 197
HIS A 274
LEU A 271
GLY A 101
PHE A  97
 None
 1.09A 5d4uB-1px8A:
undetectable		 5d4uB-1px8A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 GLY A  23
THR A  24
SER A 313
VAL A  22
 None
 1.09A 5ewuB-1px8A:
undetectable		 5ewuB-1px8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 ILE A 142
GLY A 146
PHE A  97
PHE A  89
 None
 0.94A 5hieA-1px8A:
undetectable		 5hieA-1px8A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 ILE A 142
GLY A 146
PHE A  97
PHE A  89
 None
 0.94A 5hieD-1px8A:
undetectable		 5hieD-1px8A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 TYR A 230
ARG A 324
PRO A 284
ILE A 242
 None
 1.14A 5jhdE-1px8A:
undetectable
5jhdG-1px8A:
undetectable		 5jhdE-1px8A:
18.81
5jhdG-1px8A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 5 LEU A 465
TYR A 397
LEU A 380
TYR A 477
 None
 1.30A 5ki6A-1px8A:
2.2		 5ki6A-1px8A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 TYR A 179
GLU A 172
GLY A 197
GLY A 196
 None
 0.88A 5x7pB-1px8A:
3.1		 5x7pB-1px8A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 VAL A 150
GLU A 149
ILE A 142
 None
 0.64A 6f7lB-1px8A:
undetectable		 6f7lB-1px8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 ASP A 394
GLU A 417
ASP A 416
GLU A 450
 None
 1.36A 6mn5A-1px8A:
0.0		 6mn5A-1px8A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 ASP A 394
GLU A 417
ASP A 416
GLU A 450
 None
 1.20A 6mn5B-1px8A:
undetectable		 6mn5B-1px8A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 ASP A 394
GLU A 417
ASP A 416
GLU A 450
 None
 1.18A 6mn5C-1px8A:
undetectable		 6mn5C-1px8A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1px8 BETA-XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 ASP A 394
GLU A 417
ASP A 416
GLU A 450
 None
 1.33A 6mn5D-1px8A:
0.0		 6mn5D-1px8A:
10.74