SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		4 / 7 ARG A 234
ASP A 177
ASP A 151
ARG A 232
 None
 1.44A 1cebA-1pxzA:
undetectable		 1cebA-1pxzA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		5 / 9 MET A 155
SER A 182
GLY A 181
LEU A 201
GLY A 202
 None
 1.42A 1jb0A-1pxzA:
undetectable		 1jb0A-1pxzA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		5 / 12 HIS A 119
ILE A  92
LEU A 108
VAL A 178
ILE A 187
 None
 1.25A 1zq9A-1pxzA:
undetectable		 1zq9A-1pxzA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2001_1
(SERUM ALBUMIN)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		5 / 12 ARG A 229
PHE A 222
ILE A 261
ARG A 234
GLY A 236
 None
 1.24A 2vufA-1pxzA:
undetectable		 2vufA-1pxzA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2001_1
(SERUM ALBUMIN)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		5 / 12 ARG A 229
PHE A 222
ILE A 261
ARG A 234
GLY A 236
 None
 1.35A 2vufB-1pxzA:
undetectable		 2vufB-1pxzA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		5 / 12 SER A 188
ASN A 190
THR A 186
LEU A 201
ILE A 176
 None
 1.29A 2xrlA-1pxzA:
undetectable		 2xrlA-1pxzA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		5 / 11 ILE A  92
LEU A 168
ASN A 220
LEU A 108
ILE A 123
 None
 1.32A 3a50B-1pxzA:
undetectable		 3a50B-1pxzA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		3 / 3 ASN A 194
HIS A 195
VAL A 198
 None
 0.78A 3elzB-1pxzA:
undetectable		 3elzB-1pxzA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		3 / 3 GLU A 264
HIS A 239
THR A 318
 None
 0.77A 3hkuA-1pxzA:
undetectable		 3hkuA-1pxzA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		3 / 3 SER A 120
ASP A  93
ASP A  98
 None
 0.79A 3iv6A-1pxzA:
undetectable		 3iv6A-1pxzA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		3 / 3 SER A 120
ASP A  93
ASP A  98
 None
 0.80A 3iv6C-1pxzA:
undetectable		 3iv6C-1pxzA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		3 / 3 HIS A  89
HIS A 115
MET A  33
 None
 0.80A 3mihA-1pxzA:
undetectable		 3mihA-1pxzA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		5 / 9 MET A 155
SER A 182
GLY A 181
LEU A 201
GLY A 202
 None
 1.42A 3pcqA-1pxzA:
undetectable		 3pcqA-1pxzA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		4 / 5 ARG A  18
TRP A  69
ILE A 117
ASN A 190
 None
 1.33A 4i00A-1pxzA:
undetectable		 4i00A-1pxzA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		4 / 4 THR A 128
GLY A 174
ASP A 177
SER A 172
 None
 1.37A 4rfqA-1pxzA:
undetectable		 4rfqA-1pxzA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		5 / 9 MET A 155
SER A 182
GLY A 181
LEU A 201
GLY A 202
 None
 1.42A 5l8rA-1pxzA:
undetectable		 5l8rA-1pxzA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		4 / 7 VAL A 158
ILE A 185
VAL A 116
ALA A 161
 None
 0.71A 5ospA-1pxzA:
undetectable		 5ospA-1pxzA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		4 / 7 VAL A 158
ILE A 185
VAL A 116
ALA A 161
 None
 0.70A 5osrA-1pxzA:
undetectable		 5osrA-1pxzA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 1pxz MAJOR POLLEN
ALLERGEN JUN A 1
(Juniperus
ashei) 		4 / 4 PHE A  72
LEU A 168
LEU A 101
VAL A 344
 None
 1.23A 5xxiA-1pxzA:
undetectable		 5xxiA-1pxzA:
19.21