SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1py9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 1py9 MYELIN-OLIGODENDROCY
TE GLYCOPROTEIN
(Mus
musculus) 		4 / 7 VAL A  88
VAL A  48
TYR A  51
ARG A  13
 None
 1.27A 1t46A-1py9A:
undetectable		 1t46A-1py9A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 1py9 MYELIN-OLIGODENDROCY
TE GLYCOPROTEIN
(Mus
musculus) 		4 / 6 LEU A  83
LEU A  71
ILE A  85
ARG A  84
 None
 1.04A 2rlfA-1py9A:
0.0
2rlfB-1py9A:
undetectable		 2rlfA-1py9A:
16.22
2rlfB-1py9A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 1py9 MYELIN-OLIGODENDROCY
TE GLYCOPROTEIN
(Mus
musculus) 		4 / 8 GLU A  19
VAL A  88
LEU A  22
THR A  82
 None
 0.96A 5sxqA-1py9A:
undetectable		 5sxqA-1py9A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1py9 MYELIN-OLIGODENDROCY
TE GLYCOPROTEIN
(Mus
musculus) 		4 / 8 GLU A  19
VAL A  88
LEU A  22
THR A  82
 None
 1.00A 5sxqB-1py9A:
undetectable		 5sxqB-1py9A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1py9 MYELIN-OLIGODENDROCY
TE GLYCOPROTEIN
(Mus
musculus) 		4 / 8 GLU A  19
VAL A  88
LEU A  22
THR A  82
 None
 0.98A 5sxtA-1py9A:
undetectable		 5sxtA-1py9A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1py9 MYELIN-OLIGODENDROCY
TE GLYCOPROTEIN
(Mus
musculus) 		4 / 8 GLU A  19
VAL A  88
LEU A  22
THR A  82
 None
 1.00A 5sxtB-1py9A:
undetectable		 5sxtB-1py9A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 1py9 MYELIN-OLIGODENDROCY
TE GLYCOPROTEIN
(Mus
musculus) 		4 / 8 GLU A  19
VAL A  88
LEU A  22
THR A  82
 None
 1.00A 5syjA-1py9A:
undetectable		 5syjA-1py9A:
10.70