SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pzs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		5 / 12 THR A 107
LEU A  46
LEU A  90
GLY A  88
PHE A  22
 None
 0.93A 1d4fD-1pzsA:
undetectable		 1d4fD-1pzsA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 110
ALA A  27
PHE A  22
PHE A  20
 None
 0.67A 1lqtA-1pzsA:
undetectable		 1lqtA-1pzsA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 110
ALA A  27
PHE A  22
PHE A  20
 None
 0.67A 1lquA-1pzsA:
undetectable		 1lquA-1pzsA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.48A 1rjoA-1pzsA:
undetectable		 1rjoA-1pzsA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.50A 1rkyA-1pzsA:
undetectable		 1rkyA-1pzsA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 7 SER A  87
ILE A 168
ILE A  48
THR A 107
 None
 0.99A 1sbrB-1pzsA:
undetectable		 1sbrB-1pzsA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 1v54A-1pzsA:
undetectable		 1v54A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 1v54N-1pzsA:
undetectable		 1v54N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 1v55A-1pzsA:
undetectable		 1v55A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.64A 1v55N-1pzsA:
undetectable		 1v55N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.47A 1w2zA-1pzsA:
undetectable		 1w2zA-1pzsA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.42A 1w2zB-1pzsA:
undetectable		 1w2zB-1pzsA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.44A 1w2zC-1pzsA:
undetectable		 1w2zC-1pzsA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.43A 1w2zD-1pzsA:
undetectable		 1w2zD-1pzsA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.60A 2dyrA-1pzsA:
undetectable		 2dyrA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 2dyrN-1pzsA:
undetectable		 2dyrN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.57A 2dysA-1pzsA:
undetectable		 2dysA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.58A 2dysN-1pzsA:
undetectable		 2dysN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 2eijA-1pzsA:
undetectable		 2eijA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 2eijN-1pzsA:
undetectable		 2eijN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 2eikA-1pzsA:
undetectable		 2eikA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.64A 2eikN-1pzsA:
undetectable		 2eikN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.58A 2eilA-1pzsA:
undetectable		 2eilA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 2eilN-1pzsA:
undetectable		 2eilN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.65A 2eimA-1pzsA:
undetectable		 2eimA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 2eimN-1pzsA:
undetectable		 2eimN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.52A 2einA-1pzsA:
undetectable		 2einA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.63A 2einN-1pzsA:
undetectable		 2einN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.41A 2oqeA-1pzsA:
undetectable		 2oqeA-1pzsA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.40A 2oqeB-1pzsA:
undetectable		 2oqeB-1pzsA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.41A 2oqeC-1pzsA:
undetectable		 2oqeC-1pzsA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.41A 2oqeD-1pzsA:
undetectable		 2oqeD-1pzsA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.40A 2oqeF-1pzsA:
undetectable		 2oqeF-1pzsA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.52A 2w0qA-1pzsA:
undetectable		 2w0qA-1pzsA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.45A 2w0qB-1pzsA:
undetectable		 2w0qB-1pzsA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 4 HIS A  47
HIS A  49
HIS A  75
HIS A 126
 CU  A 172 (-3.1A)
CU  A 172 (-3.2A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.12A 2wkoA-1pzsA:
18.6		 2wkoA-1pzsA:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 5 HIS A  47
HIS A  49
HIS A  75
HIS A 126
 CU  A 172 (-3.1A)
CU  A 172 (-3.2A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.19A 2wkoF-1pzsA:
18.6		 2wkoF-1pzsA:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.60A 2y69A-1pzsA:
undetectable		 2y69A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.65A 2y69N-1pzsA:
undetectable		 2y69N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.57A 2zxwA-1pzsA:
undetectable		 2zxwA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 2zxwN-1pzsA:
undetectable		 2zxwN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 3abkA-1pzsA:
undetectable		 3abkA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 3abkN-1pzsA:
undetectable		 3abkN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.56A 3ablA-1pzsA:
undetectable		 3ablA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.57A 3ablN-1pzsA:
undetectable		 3ablN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.60A 3abmA-1pzsA:
undetectable		 3abmA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 3abmN-1pzsA:
undetectable		 3abmN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.65A 3ag1A-1pzsA:
undetectable		 3ag1A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.67A 3ag1N-1pzsA:
undetectable		 3ag1N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 3ag2A-1pzsA:
undetectable		 3ag2A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 3ag2N-1pzsA:
undetectable		 3ag2N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 3ag3A-1pzsA:
undetectable		 3ag3A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 3ag3N-1pzsA:
undetectable		 3ag3N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.73A 3ag4N-1pzsA:
undetectable		 3ag4N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 3asnA-1pzsA:
undetectable		 3asnA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 3asnN-1pzsA:
undetectable		 3asnN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 3asoA-1pzsA:
undetectable		 3asoA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 3asoN-1pzsA:
undetectable		 3asoN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 3bvdA-1pzsA:
undetectable		 3bvdA-1pzsA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.66A 3dtuA-1pzsA:
undetectable		 3dtuA-1pzsA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.68A 3dtuC-1pzsA:
undetectable		 3dtuC-1pzsA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.41A 3hiiA-1pzsA:
undetectable		 3hiiA-1pzsA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  75
HIS A  49
HIS A  47
 CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.1A)
 0.42A 3hiiB-1pzsA:
undetectable		 3hiiB-1pzsA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.65A 3s33A-1pzsA:
undetectable		 3s33A-1pzsA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.65A 3s38A-1pzsA:
undetectable		 3s38A-1pzsA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 3s39A-1pzsA:
undetectable		 3s39A-1pzsA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.70A 3s3aA-1pzsA:
undetectable		 3s3aA-1pzsA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.68A 3s3bA-1pzsA:
undetectable		 3s3bA-1pzsA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.65A 3s3cA-1pzsA:
undetectable		 3s3cA-1pzsA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.58A 3s3dA-1pzsA:
undetectable		 3s3dA-1pzsA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.58A 3wg7A-1pzsA:
undetectable		 3wg7A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 3wg7N-1pzsA:
undetectable		 3wg7N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.60A 3x2qA-1pzsA:
undetectable		 3x2qA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.65A 3x2qN-1pzsA:
undetectable		 3x2qN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 8 GLU A  55
ASN A  68
GLY A  67
SER A  58
 None
 0.95A 4f93B-1pzsA:
undetectable		 4f93B-1pzsA:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_A_LYAA304_1
(FOLATE RECEPTOR BETA)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 114
THR A 111
HIS A  81
SER A  87
TYR A  76
 None
 1.46A 4kn2A-1pzsA:
0.0		 4kn2A-1pzsA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_B_LYAB304_1
(FOLATE RECEPTOR BETA)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 114
THR A 111
HIS A  81
SER A  87
TYR A  76
 None
 1.46A 4kn2B-1pzsA:
undetectable		 4kn2B-1pzsA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_1
(FOLATE RECEPTOR BETA)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 114
THR A 111
HIS A  81
SER A  87
TYR A  76
 None
 1.47A 4kn2C-1pzsA:
undetectable		 4kn2C-1pzsA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 7 ALA A  16
THR A  17
ALA A  18
LYS A  38
 None
 1.03A 4qw0K-1pzsA:
undetectable		 4qw0K-1pzsA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 7 ALA A  16
THR A  17
ALA A  18
LYS A  38
 None
 1.03A 4qw0Y-1pzsA:
undetectable		 4qw0Y-1pzsA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  46
THR A 107
ILE A 123
ALA A  18
PHE A  20
 None
 1.17A 4rp8C-1pzsA:
0.0		 4rp8C-1pzsA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 158
ALA A 133
THR A 156
THR A 155
 None
 1.42A 4w5qA-1pzsA:
undetectable		 4w5qA-1pzsA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 158
ALA A 133
THR A 156
THR A 155
 None
 1.38A 4w5rA-1pzsA:
undetectable		 4w5rA-1pzsA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 158
ALA A 133
THR A 156
THR A 155
 None
 1.40A 4w5tA-1pzsA:
undetectable		 4w5tA-1pzsA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 158
ALA A 133
THR A 156
THR A 155
 None
 1.40A 4z4cA-1pzsA:
undetectable		 4z4cA-1pzsA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 158
ALA A 133
THR A 156
THR A 155
 None
 1.40A 4z4fA-1pzsA:
undetectable		 4z4fA-1pzsA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 158
ALA A 133
THR A 156
THR A 155
 None
 1.40A 4z4gA-1pzsA:
undetectable		 4z4gA-1pzsA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 158
ALA A 133
THR A 156
THR A 155
 None
 1.41A 4z4iA-1pzsA:
undetectable		 4z4iA-1pzsA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 5b1aA-1pzsA:
undetectable		 5b1aA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 5b1aN-1pzsA:
undetectable		 5b1aN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.60A 5b1bA-1pzsA:
undetectable		 5b1bA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 5b1bN-1pzsA:
undetectable		 5b1bN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 5b3sA-1pzsA:
undetectable		 5b3sA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 5b3sN-1pzsA:
undetectable		 5b3sN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 5iy5A-1pzsA:
undetectable		 5iy5A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 5iy5N-1pzsA:
undetectable		 5iy5N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		5 / 11 ALA A 122
THR A 121
GLY A  74
GLY A  73
TYR A  76
 None
 0.84A 5lf3K-1pzsA:
undetectable
5lf3L-1pzsA:
undetectable		 5lf3K-1pzsA:
22.27
5lf3L-1pzsA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		5 / 11 ALA A 122
THR A 121
GLY A  74
GLY A  73
TYR A  76
 None
 0.84A 5lf3Y-1pzsA:
undetectable
5lf3Z-1pzsA:
undetectable		 5lf3Y-1pzsA:
22.27
5lf3Z-1pzsA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		5 / 11 ALA A 122
THR A 121
GLY A  74
GLY A  73
ALA A  72
 None
 0.80A 5lf7K-1pzsA:
undetectable
5lf7L-1pzsA:
undetectable		 5lf7K-1pzsA:
22.27
5lf7L-1pzsA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  90
GLY A  52
PHE A  20
ILE A  31
ALA A  16
 None
 1.07A 5veuH-1pzsA:
undetectable		 5veuH-1pzsA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.66A 5w97a-1pzsA:
undetectable		 5w97a-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.63A 5waua-1pzsA:
undetectable		 5waua-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 5x19A-1pzsA:
undetectable		 5x19A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.64A 5x19N-1pzsA:
undetectable		 5x19N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 5x1bA-1pzsA:
undetectable		 5x1bA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 5x1bN-1pzsA:
undetectable		 5x1bN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.67A 5x1fA-1pzsA:
undetectable		 5x1fA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.64A 5x1fN-1pzsA:
undetectable		 5x1fN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 5xdqA-1pzsA:
undetectable		 5xdqA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 5xdqN-1pzsA:
undetectable		 5xdqN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 5xdxA-1pzsA:
undetectable		 5xdxA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.63A 5xdxN-1pzsA:
undetectable		 5xdxN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.58A 5z84A-1pzsA:
undetectable		 5z84A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 5z84N-1pzsA:
undetectable		 5z84N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 5z85A-1pzsA:
undetectable		 5z85A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.60A 5z85N-1pzsA:
undetectable		 5z85N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 5z86A-1pzsA:
undetectable		 5z86A-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.64A 5z86N-1pzsA:
undetectable		 5z86N-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 5zcoA-1pzsA:
undetectable		 5zcoA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 5zcoN-1pzsA:
undetectable		 5zcoN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.58A 5zcpA-1pzsA:
undetectable		 5zcpA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.61A 5zcpN-1pzsA:
undetectable		 5zcpN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.58A 5zcqA-1pzsA:
undetectable		 5zcqA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.59A 5zcqN-1pzsA:
undetectable		 5zcqN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 4 HIS A  47
HIS A 126
HIS A  49
HIS A  75
 CU  A 172 (-3.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.2A)
CU  A 172 (-4.1A)
 1.15A 5zrdC-1pzsA:
undetectable		 5zrdC-1pzsA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		4 / 4 HIS A  47
HIS A 126
HIS A  49
HIS A  75
 CU  A 172 (-3.1A)
CU  A 172 (-3.2A)
CU  A 172 (-3.2A)
CU  A 172 (-4.1A)
 1.15A 5zrdD-1pzsA:
undetectable		 5zrdD-1pzsA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.67A 6hu9a-1pzsA:
undetectable		 6hu9a-1pzsA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.65A 6hu9m-1pzsA:
undetectable		 6hu9m-1pzsA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.57A 6nknA-1pzsA:
undetectable		 6nknA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.57A 6nknN-1pzsA:
undetectable		 6nknN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.62A 6nmfA-1pzsA:
undetectable		 6nmfA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.67A 6nmfN-1pzsA:
undetectable		 6nmfN-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.66A 6nmpA-1pzsA:
undetectable		 6nmpA-1pzsA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1pzs SUPEROXIDE DISMUTASE
[CU-ZN]
(Mycobacterium
tuberculosis) 		3 / 3 HIS A  47
HIS A  75
HIS A  49
 CU  A 172 (-3.1A)
CU  A 172 (-4.1A)
CU  A 172 (-3.2A)
 0.64A 6nmpN-1pzsA:
undetectable		 6nmpN-1pzsA:
17.28