SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pzt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA602_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 5 HIS A 261
ILE A 339
LYS A 341
PRO A 144
 None
 1.32A 2f7fA-1pztA:
0.0		 2f7fA-1pztA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		3 / 3 LEU A 240
LEU A 378
PHE A 248
 None
 0.72A 2pgrA-1pztA:
undetectable		 2pgrA-1pztA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 6 LEU A 206
LEU A 211
ILE A 215
ARG A 170
 None
 0.99A 2rlfA-1pztA:
0.0
2rlfB-1pztA:
0.0		 2rlfA-1pztA:
9.75
2rlfB-1pztA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 6 LEU A 206
LEU A 211
ILE A 215
ARG A 170
 None
 0.99A 2rlfC-1pztA:
undetectable
2rlfD-1pztA:
undetectable		 2rlfC-1pztA:
9.75
2rlfD-1pztA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 12 VAL A 396
ILE A 398
PHE A 301
LEU A 375
ALA A 239
 None
 1.25A 3apwB-1pztA:
undetectable		 3apwB-1pztA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		3 / 3 THR A 395
LYS A 156
GLU A 384
 None
 0.91A 3ijdB-1pztA:
undetectable		 3ijdB-1pztA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 12 LEU A 296
SER A 297
PHE A 301
ILE A 304
LEU A 325
 None
 1.15A 3ko0A-1pztA:
undetectable
3ko0B-1pztA:
undetectable
3ko0C-1pztA:
undetectable
3ko0D-1pztA:
undetectable		 3ko0A-1pztA:
17.80
3ko0B-1pztA:
17.80
3ko0C-1pztA:
17.80
3ko0D-1pztA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 6 LEU A 296
SER A 297
PHE A 301
ILE A 304
 None
 0.94A 3ko0B-1pztA:
undetectable		 3ko0B-1pztA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 12 LEU A 296
SER A 297
PHE A 301
ILE A 304
LEU A 325
 None
 1.16A 3ko0G-1pztA:
undetectable
3ko0H-1pztA:
undetectable
3ko0I-1pztA:
undetectable
3ko0J-1pztA:
undetectable		 3ko0G-1pztA:
17.80
3ko0H-1pztA:
17.80
3ko0I-1pztA:
17.80
3ko0J-1pztA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 11 LEU A 325
LEU A 296
SER A 297
PHE A 301
ILE A 304
 None
 1.07A 3ko0A-1pztA:
undetectable
3ko0B-1pztA:
undetectable
3ko0I-1pztA:
undetectable
3ko0J-1pztA:
undetectable		 3ko0A-1pztA:
17.80
3ko0B-1pztA:
17.80
3ko0I-1pztA:
17.80
3ko0J-1pztA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 12 LEU A 296
SER A 297
PHE A 301
ILE A 304
LEU A 325
 None
 1.14A 3ko0K-1pztA:
undetectable
3ko0L-1pztA:
undetectable
3ko0S-1pztA:
undetectable
3ko0T-1pztA:
undetectable		 3ko0K-1pztA:
17.80
3ko0L-1pztA:
17.80
3ko0S-1pztA:
17.80
3ko0T-1pztA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 12 LEU A 325
LEU A 296
SER A 297
PHE A 301
ILE A 304
 None
 1.17A 3ko0K-1pztA:
undetectable
3ko0L-1pztA:
undetectable
3ko0M-1pztA:
undetectable
3ko0N-1pztA:
undetectable		 3ko0K-1pztA:
17.80
3ko0L-1pztA:
17.80
3ko0M-1pztA:
17.80
3ko0N-1pztA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 12 LEU A 296
SER A 297
PHE A 301
ILE A 304
LEU A 325
 None
 1.18A 3ko0M-1pztA:
undetectable
3ko0N-1pztA:
undetectable
3ko0O-1pztA:
undetectable
3ko0P-1pztA:
undetectable		 3ko0M-1pztA:
17.80
3ko0N-1pztA:
17.80
3ko0O-1pztA:
17.80
3ko0P-1pztA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 12 LEU A 325
LEU A 296
SER A 297
PHE A 301
ILE A 304
 None
 1.09A 3ko0M-1pztA:
undetectable
3ko0N-1pztA:
undetectable
3ko0O-1pztA:
undetectable
3ko0P-1pztA:
undetectable		 3ko0M-1pztA:
17.80
3ko0N-1pztA:
17.80
3ko0O-1pztA:
17.80
3ko0P-1pztA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 6 LEU A 296
SER A 297
PHE A 301
ILE A 304
 None
 0.91A 3ko0S-1pztA:
undetectable		 3ko0S-1pztA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 5 ILE A 339
PRO A 335
LYS A 341
GLY A 340
 None
 1.07A 3tkdB-1pztA:
undetectable		 3tkdB-1pztA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 5 ILE A 339
PRO A 335
LYS A 341
GLY A 340
 None
 1.08A 3tkdA-1pztA:
undetectable		 3tkdA-1pztA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 12 PHE A 226
GLY A 313
ALA A 221
GLY A 222
ASN A 219
 None
 1.30A 3v3oB-1pztA:
0.4		 3v3oB-1pztA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 8 GLY A 169
LEU A 155
VAL A 158
GLU A 159
 None
 0.82A 4fgzA-1pztA:
undetectable		 4fgzA-1pztA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 7 ILE A 185
GLY A 169
ALA A 239
GLN A 207
 None
 0.96A 4g0uB-1pztA:
0.7		 4g0uB-1pztA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		5 / 11 PRO A 285
PHE A 280
ASP A 318
GLY A 291
TYR A 289
 None
 1.30A 4lxzB-1pztA:
undetectable		 4lxzB-1pztA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 5 PHE A 267
PRO A 270
ALA A 295
PHE A 290
 SO4  A 403 (-4.7A)
None
None
None
 1.09A 4z4cA-1pztA:
undetectable		 4z4cA-1pztA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		3 / 3 ILE A 256
PRO A 257
ILE A 147
 None
 0.46A 5hw8F-1pztA:
undetectable		 5hw8F-1pztA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		4 / 5 TYR A 216
ILE A 394
LEU A 167
GLY A 168
 None
 0.84A 5kmdC-1pztA:
undetectable
5kmdD-1pztA:
undetectable		 5kmdC-1pztA:
19.57
5kmdD-1pztA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1pzt BETA-1,4-GALACTOSYLT
RANSFERASE 1
(Bos
taurus) 		3 / 3 ARG A 228
LEU A 232
PHE A 236
 None
 0.72A 6nknP-1pztA:
undetectable		 6nknP-1pztA:
19.81