SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1pzv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A83_A_DXCA1160_0 (MAJOR POLLEN ALLERGEN BET V 1-A)	1pzv	PROBABLE UBIQUITIN-CONJUGATIN G ENZYME E2-19 KDA (Caenorhabditis elegans)	5 / 12	PRO A 134 LEU A 126 ILE A 76 GLN A 143 ALA A 139	None	1.40A	4a83A-1pzvA: undetectable	4a83A-1pzvA: 22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1475_0 (MJ0495-LIKE PROTEIN)	1pzv	PROBABLE UBIQUITIN-CONJUGATIN G ENZYME E2-19 KDA (Caenorhabditis elegans)	4 / 8	ILE A 81 ILE A 76 VAL A 40 GLY A 42	None	0.66A	4ac9C-1pzvA: undetectable	4ac9C-1pzvA: 15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1475_0 (TRANSLATION ELONGATION FACTOR SELB)	1pzv	PROBABLE UBIQUITIN-CONJUGATIN G ENZYME E2-19 KDA (Caenorhabditis elegans)	4 / 8	ILE A 81 ILE A 76 VAL A 40 GLY A 42	None	0.59A	4acaC-1pzvA: undetectable	4acaC-1pzvA: 15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1475_0 (TRANSLATION ELONGATION FACTOR SELB)	1pzv	PROBABLE UBIQUITIN-CONJUGATIN G ENZYME E2-19 KDA (Caenorhabditis elegans)	4 / 8	ILE A 81 ILE A 76 VAL A 40 GLY A 42	None	0.64A	4acbC-1pzvA: undetectable	4acbC-1pzvA: 15.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4A83_A_DXCA1160_0","MAJOR POLLEN ALLERGEN BET V 1-A","1pzv","PROBABLE UBIQUITIN-CONJUGATING ENZYME E2-19 KDA","Caenorhabditis elegans",5,"PRO A 134;LEU A 126;ILE A  76;GLN A 143;ALA A 139","None","1.40A","4a83A-1pzvA:undetectable","4a83A-1pzvA:22.29"],["4AC9_C_DXCC1475_0","MJ0495-LIKE PROTEIN","1pzv","PROBABLE UBIQUITIN-CONJUGATING ENZYME E2-19 KDA","Caenorhabditis elegans",4,"ILE A  81;ILE A  76;VAL A  40;GLY A  42","None","0.66A","4ac9C-1pzvA:undetectable","4ac9C-1pzvA:15.70"],["4ACA_C_DXCC1475_0","TRANSLATION ELONGATION FACTOR SELB","1pzv","PROBABLE UBIQUITIN-CONJUGATING ENZYME E2-19 KDA","Caenorhabditis elegans",4,"ILE A  81;ILE A  76;VAL A  40;GLY A  42","None","0.59A","4acaC-1pzvA:undetectable","4acaC-1pzvA:15.70"],["4ACB_C_DXCC1475_0","TRANSLATION ELONGATION FACTOR SELB","1pzv","PROBABLE UBIQUITIN-CONJUGATING ENZYME E2-19 KDA","Caenorhabditis elegans",4,"ILE A  81;ILE A  76;VAL A  40;GLY A  42","None","0.64A","4acbC-1pzvA:undetectable","4acbC-1pzvA:15.70"]]